Unnecessary Antibiotic Use Continues for Children with Sore Throat
Emergency Medicine Summary and Comment
The rate of antibiotic prescribing greatly exceeds the prevalence of GABHS in children with sore throat.
By John A. Marx, MD, FAAEM, FACEP
January 31, 2006
Covering:
Linder JA et al., JAMA 2005 Nov 9; 294:2315-22
Pediatric Prescription Writing Fraught with Potential Error
Emergency Medicine Summary and Comment
Fifteen percent of outpatient pediatric prescriptions contained potential errors, and computerized physician order entry did not reduce error rates.
By Jill M. Baren, MD, FACEP, FAAP
January 31, 2006
Covering:
McPhillips HA et al., J Pediatr 2005 Dec; 147:761-7
Rotavirus Vaccines Are Coming Soon
Promising results for two new rotavirus vaccines
By Howard Bauchner, MD
January 27, 2006
Covering:
Ruiz-Palacios GM et al., N Engl J Med 2006 Jan 5; 354:11-22
Vesikari T et al., N Engl J Med 2006 Jan 5; 354:23-33
Glass RI and Parashar UD., N Engl J Med 2006 Jan 5; 354:75-7
Two New Rotavirus Vaccines Show Promise
Infectious Diseases Summary and Comment
In the largest prelicensure vaccine-safety trials ever held, no increased risk for intussusception was identified with either vaccine.
By Robert S. Baltimore, MD
January 27, 2006
Covering:
Vesikari T et al., N Engl J Med 2006 Jan 5; 354:23-33
Ruiz-Palacios GM et al., N Engl J Med 2006 Jan 5; 354:11-22
C. difficile –Associated Diarrhea: More Virulent, More Common
The frequency, virulence, and complications of CDAD are increasing.
By Peggy Sue Weintrub, MD
January 27, 2006
Covering:
Centers for Disease Control and Prevention., MMWR Morb Mortal Wkly Rep 2005 Dec 2; 54:1201-5
Loo VG et al., N Engl J Med 2005 Dec 8; 353:2442-9
McDonald LC et al., N Engl J Med 2005 Dec 8; 353:2433-41
Petting Zoo–Associated E. coli O157:H7 Infection
Infectious Diseases Summary and Comment
Illness from toxigenic <$EMPH_O>E. coli<$EMPH_C> is usually foodborne, but some serious outbreaks have been associated with animal contact.
By Stephen G. Baum, MD
January 27, 2006
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2005 Dec 23; 54:1277-80
Live Intranasal Influenza Vaccine: Adverse Events Are Minimal
During the first 2 years after licensure, no unexpected serious risks were identified with use according to approved indications.
By Richard T. Ellison III, MD
January 27, 2006
Covering:
Izurieta HS et al., JAMA 2005 Dec 7; 294:2720-5
New Data on Treating Bronchiolitis
In the absence of any medication that consistently and effectively treats bronchiolitis in young children, therapeutic efficacy should be assessed case by case.
By Robert A. Dershewitz, MD, MSc
January 27, 2006
Covering:
Modl M et al., J Pediatr 2005 Nov; 147:617-21
Amirav I et al., J Pediatr 2005 Nov; 147:627-31
Rotavirus Vaccines Are Coming Soon
General Medicine Summary and Comment
Free
Promising results for two new rotavirus vaccines
By Howard Bauchner, MD
January 24, 2006
Covering:
Ruiz-Palacios GM et al., N Engl J Med 2006 Jan 5; 354:11-22
Vesikari T et al., N Engl J Med 2006 Jan 5; 354:23-33
Glass RI and Parashar UD., N Engl J Med 2006 Jan 5; 354:75-7
Fluconazole Is Not Very Effective for Pediatric Tinea Capitis
Dermatology Summary and Comment
The incidence of tinea capitis infection is steadily rising in the U.S. Oral griseofulvin remains the only FDA-approved therapy for tinea capitis in children, but . . .
By Mary Wu Chang, MD
January 17, 2006
Covering:
Foster KW et al., J Am Acad Dermatol 2005 Nov; 53:798-809
Surveillance for Influenza-Related Deaths of Children
Infectious Diseases Summary and Comment
Free
CDC surveillance shows 153 influenza-associated deaths in U.S. children during the 2003–2004 flu season.
By Robert S. Baltimore, MD
January 13, 2006
Covering:
Bhat N et al., N Engl J Med 2005 Dec 15; 353:2559-67
Zinc Supplements Safe in HIV-Infected Children
Infectious Diseases Summary and Comment
Zinc supplementation is safe and effective in HIV-infected children and should be used in areas where zinc deficiency is common.
By Mary E. Wilson, MD
January 13, 2006
Covering:
Bobat R et al., Lancet 2005 Nov 26; 366:1862-7
Dear Reader,
Coverage of the important topic of pediatric vaccination has been notable in the literature of late. JWPAM has published five recent summaries in this area . . .
By F. Bruder Stapleton, MD
January 12, 2006
Hepatitis A Vaccination Recommended for All U.S. Children
In 1999, the CDC Advisory Committee on Immunization Practices (ACIP) recommended hepatitis A vaccination for children in the 11 western U.S. states where the incidence . . .
By Peggy Sue Weintrub, MD
January 12, 2006
Covering:
Centers for Disease Control and Prevention (CDC).,
Influenza Vaccine: Expanding Indications for Children with Neuromuscular Disease
The CDC Advisory Committee on Immunization Practices (ACIP) has recently recommended influenza vaccination for many high-risk groups, including patients with hemoglobinopathies; patients receiving long-term salicylate . . .
By Peggy Sue Weintrub, MD
January 12, 2006
Covering:
Keren R et al., JAMA 2005 Nov 2; 294:2188-94
BCG Vaccination: Does It Protect Against TB Infection?
Bacille Calmette-Guérin (BCG) vaccination complicates diagnosis of Mycobacterium tuberculosis (TB) infection. The recently developed ELISpot assay identifies interferon-γ-producing T-cells that respond to unique TB antigens . . .
By F. Bruder Stapleton, MD
January 12, 2006
Covering:
Soysal A et al., Lancet 2005 Oct 22; 366:1443-51
Lienhardt C and Zumla A., Lancet 2005 Oct 22; 366:1414-6
Pediatric HIV Treatment Guidelines Revised
Pediatric HIV treatment guidelines from DHHS/IDSA were recently updated to include information on tipranavir and on new formulations of FTC and lopinavir/ritonavir. The full text . . .
