Oseltamivir Prevents Complications of Influenza in High-Risk Children
Oseltamivir prescribed within 1 day of clinical diagnosis of influenza reduced risks for complications and hospitalization in children with chronic conditions.
STIs in Children When Sexual Abuse Is Suspected
Comprehensive testing is important in such children. Nucleic acid amplification tests on urine specimens were more sensitive than culture for detecting <$EMPH_O>C. trachomatis<$EMPH_C> and <$EMPH_O>N. gonorrhoeae.<$EMPH_C>
By Howard Bauchner, MD
July 29, 2009
Covering:
Girardet RG et al., Pediatrics 2009 Jul; 124:79
Black CM et al., Pediatr Infect Dis J 2009 Jul; 28:608
Increasing Chlamydia Screening Rates in Adolescent Girls
By redesigning work flow during urgent care visits, physicians can increase chlamydia screening rates among sexually active teens.
By Robin Drucker, MD
July 22, 2009
Covering:
Tebb KP et al., Arch Pediatr Adolesc Med 2009 Jun; 163:559
Managing Skin and Soft-Tissue Infections in Children
General Medicine
Summary and Comment
Trimethoprim-sulfamethoxazole might not be effective as initial monotherapy for skin infections in children.
By Howard Bauchner, MD
July 16, 2009
Covering:
Elliott DJ et al., Pediatrics 2009 Jun; 123:e959
Looking Far Afield . . .
Researchers model an ingenious strategy for vector eradication in dengue fever.
Immature WBCs in CSF Do Not Indicate Bacterial Meningitis
Emergency Medicine
Summary and Comment
Free
In this retrospective study, band forms in CSF of children with meningitis did not predict bacterial etiology.
By Daniel J. Pallin, MD, MPH
July 10, 2009
Covering:
Kanegaye JT et al., Pediatrics 2009 Jun; 123:e967
West Nile Virus Disease in Children
Infectious Diseases
Summary and Comment
Children had a lower incidence of West Nile virus disease than adults and a lower rate of CNS involvement than older adults.
Obtaining Urine Specimens in Young Children: Bag vs. Catheter
General Medicine
Summary and Comment
Dont rely on bag-obtained specimens alone.
Treatment of Noncultured Skin Infections in the Age of CA-MRSA
Emergency Medicine
Summary and Comment
In this retrospective study, cephalosporins were equivalent to clindamycin and superior to trimethoprim-sulfamethoxazole.
By Daniel J. Pallin, MD, MPH
July 2, 2009
Covering:
Elliott DJ et al., Pediatrics 2009 Jun; 123:e959
Vaccine Refusal Increases Risk for Pertussis in Unvaccinated Children
Herd immunity did not protect children whose parents refused vaccination.
Did You Really Have Chicken Pox?
A reported history of chickenpox is not highly predictive of varicella immunity in patients born after 1989.
Severe RSV Infection and Asthma
Infectious Diseases
Summary and Comment
Free
Results from a twin study suggest that severe RSV infection does not cause asthma, but rather indicates a genetic predisposition to asthma.
By Neil M. Ampel, MD
June 24, 2009
Covering:
Thomsen SF et al., Am J Respir Crit Care Med 2009 Jun 15; 179:1091
Universal Screening for Group B Strep: Success with Room for Improvement
Missed opportunities for prevention include women who deliver preterm and women with unknown or false-negative screening results.
Treating Childrens Skin and Soft-Tissue Infections
Infectious Diseases
Summary and Comment
Specifically aiming empirical antibiotic treatment at MRSA may not be beneficial.
Rotavirus Vaccine in a Developing Country
Infectious Diseases
Summary and Comment
In Nicaragua, rotavirus vaccine was less effective than in higher-income countries but was still highly protective against very severe diarrhea.
Bleach Baths for Atopic Dermatitis
Dermatology
Summary and Comment
Free
Combined treatment with sodium hypochlorite and nasal mupirocin improved eczema severity, but we dont yet know how or why.
Cephalosporins in Patients with Penicillin Allergy: Use Them . . . but Be Careful
Patients with penicillin allergy are not necessarily allergic to cephalosporins.
Short vs. Long Course of Antibiotics for Pediatric Septic Arthritis
A short 10-day course was sufficient in uncomplicated cases.
Neonatal CMV Infection in Breast-Fed Preemies
Infectious Diseases
Summary and Comment
Only 9 of 62 premature infants breast-fed by CMV-positive mothers became infected; long-term outcomes were good.
New Treatment for Bronchiolitis in Infants
Nebulized 3% saline in conjunction with bronchodilators shortened hospital stay and lowered clinical severity.
By Howard Bauchner, MD
May 13, 2009
Covering:
Zhang L et al., Cochrane Database Syst Rev 2008 Oct 8
Combined Epinephrine and Dexamethasone Therapy for Bronchiolitis?
Emergency Medicine
Summary and Comment
Free
This study did not show clear benefit for combination therapy with nebulized epinephrine and oral dexamethasone.
Inhaled Steroids Do Not Prevent Recurrent RSV-Induced Bronchiolitis
Emergency Medicine
Summary and Comment
Free
In infants admitted with RSV infection, early use of inhaled beclomethasone did not reduce the number of days or proportion of patients with wheeze at 1 year.
The CDCs Report on the New Swine-Origin Influenza A (H1N1) Virus
The formal surveillance report of the widely reported cases of S-OIV infection
By Peggy Sue Weintrub, MD
May 8, 2009
Covering:
Dawood FS et al., N Engl J Med 2009 May 7
Belshe RB., N Engl J Med 2009 May 7
Miller MA et al., 2009 May 7
Brownstein JS et al., N Engl J Med 2009 May 21; 360:2153
Vaccines: Still Key to Child and Community Health
A shift in public perception about vaccine safety threatens the success of immunization programs.
UTI in Preterm Infants
Breast-feeding was associated with lower risk for UTI.