Measles Outbreak in the U.S. — Why?
Infectious Diseases Summary and Comment
Free
Measles was introduced into Indiana by an unvaccinated girl who spread it to 33 others, nearly all of them unvaccinated.
By Neil R. Blacklow, MD
August 2, 2006
Covering:
Parker AA et al., N Engl J Med 2006 Aug 3; 355:447-55
Progress Against Opportunistic Infections in HIV-Infected Children
Infectious Diseases Summary and Comment
Improvement in the immunologic status of HIV-infected children since the introduction of potent combination ART is associated with reduced incidence of many common infections.
By Robert S. Baltimore, MD
August 2, 2006
Covering:
Gona P et al., JAMA 2006 Jul 19; 296:292-300
Late-Onset Subacute Sclerosing Panencephalitis
Neurology Summary and Comment
Patients with onset after age 17 appear to have a somewhat extended period of susceptibility after measles exanthema.
By Paul Richard Dyken, MD
August 1, 2006
Covering:
Prashanth LK et al., J Neurol Neurosurg Psychiatry 2006 May; 77:630-3
Dangerous Shoes: Another Sports Risk
Dermatology Summary and Comment
<$EMPH_O>S. aureus<$EMPH_C>-related toxic shock syndrome can develop in benign wounds.
By Jan V. Hirschmann, MD
July 28, 2006
Covering:
Taylor CM et al., BMJ 2006 Jun 10; 332:1376-8
Influenza: The Burden of Disease in Children
It’s often unrecognized.
By Howard Bauchner, MD
July 26, 2006
Covering:
Poehling KA et al., N Engl J Med 2006 Jul 6; 355:31-40
Glezen WP., N Engl J Med 2006 Jul 6; 355:79-81
A Potential Vaccine for the Group B Meningococcus
Infectious Diseases Summary and Comment
Free
Genomic analysis has led to a candidate vaccine against group B <$EMPH_O>Neisseria meningitidis.<$EMPH_C>
By Richard T. Ellison III, MD
July 26, 2006
Covering:
Giuliani MM et al., Proc Natl Acad Sci U S A 2006 Jul 18; 103:10834-9
Is Preadmission Antibiotic Treatment for Suspected Meningococcal Infection Effective?
General Medicine Summary and Comment
The benefit of preadmission antibiotics remains uncertain.
By Robert A. Dershewitz, MD, MSc
July 25, 2006
Covering:
Harnden A et al., BMJ 2006 Jun 3; 332:1295-8
Hahné SJM et al., BMJ 2006 Jun 3; 332:1299-303
Keeley D., BMJ 2006 Jun 3; 332:1283-4
Meningococcal Disease in the Office: To Treat or Not to Treat?
The effectiveness of antibiotic treatment before hospital admission remains uncertain.
By Peggy Sue Weintrub, MD
July 19, 2006
Covering:
Harnden A et al., BMJ 2006 Jun 3; 332:1295-8
Hahné SJM et al., BMJ 2006 Jun 3; 332:1299-303
Perera R., BMJ 2006 Jun 3; 332:1297-8
Flu During Pregnancy and the Risk to Offspring
Offspring with some congenital abnormalities were more likely to have a mother who had flu during pregnancy.
By Judith G. Hall, OC, MD
July 19, 2006
Covering:
Acs N et al., Birth Defects Res A Clin Mol Teratol 2005 Dec; 73:989-96
Prehospital Parenteral Antibiotics for Suspected Meningococcal Disease?
Infectious Diseases Summary and Comment
Despite several studies on the effects of prehospital parenteral treatment of suspected meningococcal disease, benefits remain unproven.
By Stephen G. Baum, MD
July 19, 2006
Covering:
Harnden A et al., BMJ 2006 Jun 3; 332:1295-8
Hahné SJM et al., BMJ 2006 Jun 3; 332:1299-303
Perera R., BMJ 2006 Jun 3; 332:1297-8
What Is the True Burden of Influenza in Children?
Infectious Diseases Summary and Comment
Free
The burden is substantial, yet most cases go undiagnosed, both in the doctor’s office and in the hospital.
By Robert S. Baltimore, MD
July 19, 2006
Covering:
Poehling KA et al., N Engl J Med 2006 Jul 6; 355:31-40
Glezen WP., N Engl J Med 2006 Jul 6; 355:79-81
Tattooing: Another Risk for Methicillin-Resistant S. aureus
CDC reports six clusters of MRSA infection among 44 tattoo recipients.
By Peggy Sue Weintrub, MD
July 12, 2006
Covering:
MMWR Morb Mortal Wkly Rep 2006 Jun 23; 55:677-9
Nitazoxanide: Potential New Tool for Treating Rotavirus Diarrhea
Infectious Diseases Summary and Comment
Free
An oral suspension of nitazoxanide significantly shortened the duration of severe rotavirus diarrhea in hospitalized children in Egypt.
By Mary E. Wilson, MD
July 12, 2006
Covering:
Rossignol JF et al., Lancet 2006 Jul 8; 368:124-9
Necrotizing Soft Tissue Infections: Difficult to Diagnose in Immunocompromised Patients
The disorder may present differently in immunocompromised children.
By William P. Kanto, Jr., MD
June 29, 2006
Covering:
Butterworth SA and Murphy JJ., J Pediatr Surg 2006 May; 41:935-9
Meningococcal Conjugate Vaccine: Short Supply
Vaccine delay recommended for 11- to 12-year-olds.
By Peggy Sue Weintrub, MD
June 9, 2006
Botulism Immune Globulin as a Therapy for Infant Botulism
Neurology Summary and Comment
Human botulism immune globulin facilitated recovery in cases of infant botulism in a randomized, placebo-controlled trial.
By Peter B. Kang, MD
June 22, 2006
Covering:
Arnon SS et al., N Engl J Med 2006 Feb 2; 354:462-71
Evolution of Perinatal HCV
Infectious Diseases Summary and Comment
Infants infected with hepatitis C virus can develop HCV genetic variants if their inflammatory response is weak.
By Robert S. Baltimore, MD
June 9, 2006
Covering:
Farci P et al., Proc Natl Acad Sci U S A 2006 May 30; 103:8475-80
Mumps Outbreak in the U.S. Midwest
As of May 2, nearly 3000 cases have been reported to the CDC.
By Peggy Sue Weintrub, MD
May 26, 2006
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2006 May 26; 55:559-63
Ondansetron Improves Success of Oral Rehydration for Gastroenteritis
Infectious Diseases Summary and Comment
For children with mild-to-moderate dehydration due to gastroenteritis, ondansetron greatly reduced the likelihood of vomiting and of needing IV fluids.
By Robert S. Baltimore, MD
May 19, 2006
Covering:
Freedman SB et al., N Engl J Med 2006 Apr 20; 354:1698-705
Fever in 2- to 6-Month-Old Infants
General Medicine Summary and Comment
Free
Fever in infants older than 2 months can be associated with serious bacterial infections, particularly UTIs.
By Howard Bauchner, MD
May 16, 2006
Covering:
Hsiao AL et al., Pediatrics 2006 May; 117:1695-701
Humidity of No Value for Croup
Emergency Medicine Summary and Comment
Even when delivered in small droplets that can deposit in the larynx.
By John A. Marx, MD, FAAEM, FACEP
May 9, 2006
Covering:
Scolnik D et al., JAMA 2006 Mar 15; 295:1274-80
Mumps! It’s Baaaack!
Emergency Medicine Summary and Comment
Parotitis is the tip-off!
By Diane M. Birnbaumer, MD, FACEP
May 9, 2006
Covering:
MMWR Morb Mortal Wkly Rep 2006 Apr 7; 55:366-8MMWR Morb Mortal Wkly Rep 2006 Apr 14; 55:401-2
Community-Acquired MRSA Infections: Now in Newborns, Too
Emergency Medicine Summary and Comment
MRSA carriers and poor infection-control practices in hospital nurseries are the likely culprits.
By Diane M. Birnbaumer, MD, FACEP
May 9, 2006
Covering:
MMWR Morb Mortal Wkly Rep 2006 Mar 31; 55:329-32
Mist Doesn’t Work for Croup
. . . even when administered in particle sizes optimized to reach the larynx.
By F. Bruder Stapleton, MD
May 5, 2006
Covering:
Scolnik D et al., JAMA 2006 Mar 15; 295:1274-80
Pneumococcal Conjugate Vaccine: Protection in Infancy
Rates of invasive pneumococcal disease have declined since the vaccine's introduction, even among infants too young to be vaccinated.
By Peggy Sue Weintrub, MD
May 5, 2006
Covering:
Poehling KA et al., JAMA 2006 Apr 12; 295:1668-74
