Evaluation of Children with Periorbital Swelling
Classic signs of proptosis, ophthalmoplegia, and pain with external ocular movements were absent in 50% of children with orbital infections.
Is Autism in Children Associated with Previous Infection?
Infectious Diseases
Summary and Comment
The rate of autism spectrum disorders was slightly increased among children who had previously been hospitalized for infectious — or noninfectious — causes.
Congenital Syphilis Makes a Comeback
Dermatology
Summary and Comment
In light of a resurgence, clinicians need to remember the clinical features of syphilis in infants.
By Jan V. Hirschmann, MD
May 7, 2010
Covering:
Centers for Disease Control (CDC)., MMWR Morb Mortal Wkly Rep 2010 Apr 16; 59:413
Recent Trends in Congenital Syphilis and Herpes Simplex Virus Prevalence
Rates of congenital syphilis are rising; HSV rates are stable but still worrisome.
By Peggy Sue Weintrub, MD
May 5, 2010
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2010 Apr 16; 59:413
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2010 Apr 23; 59:456
Risk Stratification of Children with Periorbital Infections
Emergency Medicine
Summary and Comment
A recursive partitioning model identifies risk for intraorbital abscess.
By Katherine Bakes, MD
April 30, 2010
Covering:
Rudloe TF et al., Pediatrics 2010 Apr; 125:e719
Screening for Congenital Cytomegalovirus: Polymerase Chain Reaction vs. Culture
PCR analysis of newborn dried blood spots had low sensitivity compared to traditional culture of saliva — the focus remains on prevention.
By Peggy Sue Weintrub, MD
April 28, 2010
Covering:
Boppana SB et al., JAMA 2010 Apr 14; 303:1375
Bale JF Jr., JAMA 2010 Apr 14; 303:1425
Tropheryma whipplei and Gastroenteritis in Children
Infectious Diseases
Summary and Comment
<$EMPH_O>Tropheryma whipplei<$EMPH_C> was found in 15% of young children with gastroenteritis, one third of whom were coinfected with other diarrhea pathogens.
By Mary E. Wilson, MD
April 28, 2010
Covering:
Raoult D et al., Emerg Infect Dis 2010 May; 16:776
Generalized Petechial Rashes in Children with Parvovirus B19
Emergency Medicine
Summary and Comment
Parvovirus was the most common cause of generalized petechial rashes during a 2007 pediatric parvovirus B19 outbreak.
By Katherine Bakes, MD
April 23, 2010
Covering:
Edmonson MB et al., Pediatrics 2010 Apr; 125:e787
Predictors of Unscheduled Return Visits for Bronchiolitis After Emergency Department Discharge
Emergency Medicine
Summary and Comment
Age <2 months, male sex, and previous hospitalization were predictors of unscheduled visits within 2 weeks of discharge in children younger than 2 years with bronchiolitis.
By Katherine Bakes, MD
April 23, 2010
Covering:
Norwood A et al., Acad Emerg Med 2010 Apr; 17:376
Shifting Pneumococcal Serotypes
Infectious Diseases
Summary and Comment
Free
In Massachusetts, the incidence of invasive pneumococcal infection fell after introduction of the heptavalent conjugated pneumococcal vaccine, then stabilized because of infections from nonvaccine serotypes.
Pink Eye: To Treat or Not to Treat?
Four clinical factors helped identify children at low risk for bacterial conjunctivitis.
By Robin Drucker, MD
April 7, 2010
Covering:
Meltzer JA et al., Arch Pediatr Adolesc Med 2010 Mar; 164:263
Leucocytosis and Risk for Serious Bacterial Infection in Young Children
Consider pneumonia in a young febrile child with white blood cell counts >25,000/mm3 .
Red Flags That Signal Serious Illness in Children
Parental concern and clinician's instinct that the illness is serious are among the key distinguishing features.
By F. Bruder Stapleton, MD
March 31, 2010
Covering:
Van den Bruel A et al., Lancet 2010 Mar 6; 375:834
Dawes M., Lancet 2010 Mar 6; 375:784
Pediatric Clostridium difficile Infections Increasing
Infectious Diseases
Summary and Comment
From 1997 through 2006, the incidence of <$EMPH_O>C. difficile<$EMPH_C> infections increased from 7.24 to 12.8 per 10,000 pediatric hospitalizations in the U.S.
By Mary E. Wilson, MD
March 31, 2010
Covering:
Zilberberg MD et al., Emerg Infect Dis 2010 Apr
Vaccination Protects Against Most Invasive Pneumococcal Infections
Emergency Medicine
Summary and Comment
Most invasive pneumococcal infections in vaccinated children are caused by serotypes that are not covered by the pneumococcal conjugate vaccine.
Influenza Vaccine: Protecting Children Protects Everyone
In a community-based randomized study, immunization of children and adolescents provided 61% protection against influenza in the unimmunized community.
Vaccine Update: FDA Approves New Pneumococcal Vaccine
13-valent pneumococcal vaccine approved, flu vaccine recommendation made universal
Positive Urine Cultures: Do I Hear Ten to the Sixth?
Changing the definition of a positive voided urine culture from 10exp5 to 10exp6 cfu/mL reduces false-positive results without sacrificing sensitivity.
Imaging for Periorbital Infections
Infectious Diseases
Summary and Comment
Investigators created an algorithm for distinguishing which patients with acute periorbital findings at presentation might benefit most from computed tomography scans.
Dead Head: Ivermectin vs. Malathion for Hard-to-Treat Lice
Dermatology
Summary and Comment
Free
Oral ivermectin is an effective backup when topical treatment fails.
By Mark V. Dahl, MD
March 10, 2010
Covering:
Chosidow O et al., N Engl J Med 2010 Mar 11; 362:896
Reducing Catheter-Associated Bloodstream Infections in Children
Infectious Diseases
Summary and Comment
Compliance with special policies for insertion and maintenance of central venous catheters was associated with a 43% reduction in the infection rate.
Maternal Flu and the Postnatal Brain: An Animal Study
Psychiatry
Summary and Comment
In rhesus monkeys, titers of virus-specific immunoglobulin are associated with brain abnormalities.
By Barbara Geller, MD
March 1, 2010
Covering:
Short SJ et al., Biol Psychiatry 2010 Jan 13
Update on Evaluation and Treatment of Bronchiolitis
Emergency Medicine
Summary and Comment
Free
Recent evidence supports the 2006 American Academy of Pediatrics recommendations for the evaluation and treatment of bronchiolitis.
By Katherine Bakes, MD
February 26, 2010
Covering:
Zorc JJ and Hall CB., Pediatrics 2010 Feb; 125:342
Dengue Virus Infections in Infants
Infectious Diseases
Summary and Comment
In a dengue-endemic area, the incidence of dengue infection exceeded 10% in infants aged 2–15 months; illness was generally mild or asymptomatic.
By Mary E. Wilson, MD
February 24, 2010
Covering:
Capeding RZ et al., Am J Trop Med Hyg 2010 Feb; 82:330
Dosing Cups for Children's Liquid Medications: Overdoses Are Common
Dermatology
Summary and Comment
Parents and guardians must be taught to measure correctly, and better measuring devices are needed to prevent dosing errors.
By Mary Wu Chang, MD
February 19, 2010
Covering:
Yin HS et al., Arch Pediatr Adolesc Med 2010 Feb; 164:181