Modifiable Factors That Increase Mortality After Hip Fracture
General Medicine Summary and Comment
Delayed surgery and general anesthesia were associated with worse outcomes.
By Allan S. Brett, MD
January 15, 2008
Covering:
Radcliff TA et al., J Bone Joint Surg Am 2008 Jan; 90:34
If a Bone Breaks, Think Osteoporosis
Women's Health Summary and Comment
Both high- and low-trauma fractures could indicate underlying osteoporosis.
By Wendy S. Biggs, MD
January 10, 2008
Covering:
Mackey DC et al., JAMA 2007 Nov 28; 298:2381
Are Simple Tools Effective for Assessing Hip Fracture Risk?
Women's Health Summary and Comment
Eleven clinical variables predicted 5-year hip fracture risk almost as well as did bone densitometry.
By Wendy S. Biggs, MD
January 10, 2008
Covering:
Robbins J et al., JAMA 2007 Nov 28; 298:2389
Etiology of Knee Buckling
Neurology Summary and Comment
Sudden loss of support at the knee commonly has a musculoskeletal etiology.
By George Plotkin, MD, PhD
January 8, 2008
Covering:
Felson DT et al., Ann Intern Med 2007 Oct 16; 147:534
Benefits and Risks of Long-Term Alendronate
The FLEX study results help us determine for whom long-term alendronate therapy is beneficial.
Depression and Low Bone Mass
General Medicine Summary and Comment
Free
Depressed women had lower BMD and higher levels of several proinflammatory markers.
ANCA Levels and Disease Activity in Wegener Granulomatosis
General Medicine Summary and Comment
Increased ANCA levels in patients in sustained remission should not prompt presumptive therapy without clinical evidence of disease activity.
By Deborah M. DeMarco, MD
December 18, 2007
Covering:
Finkielman JD et al., Ann Intern Med 2007 Nov 6; 147:611
Dabigatran: A New Oral Anticoagulant
In a large study, dabigatran was as effective as low-dose enoxaparin for preventing VTE after knee replacement.
By David Green, MD, PhD
December 18, 2007
Covering:
Eriksson BI et al., J Thromb Haemost 2007 Nov; 5:2178
Bauer KA., J Thromb Haemost 2007 Nov; 5:2175
Depression: Can You Feel It in Your Bones Even After It’s Gone?
Psychiatry Summary and Comment
An observational study confirms depression as a risk factor for osteoporosis in women.
By Peter Roy-Byrne, MD
December 17, 2007
Covering:
Eskandari F et al., Arch Intern Med 2007 Nov 26; 167:2329
Clinical Predictors of Hip Fracture in Postmenopausal Women
General Medicine Summary and Comment
Free
A new algorithm accurately predicts 5-year risk; the next step is to test its clinical utility prospectively.
Lumbar Supports Prevent Recurrent Low Back Pain in the Workplace
General Medicine Summary and Comment
Elastic back supports reduced recurrence of low back pain among home-care workers.
High-Trauma Fractures and Osteoporosis
General Medicine Summary and Comment
Osteoporosis predicts high-trauma as well as low-trauma fractures.
Acute Lower Back Pain: Keep Things Simple
General Medicine Summary and Comment
Free
NSAIDs and spinal manipulation did nothing to speed recovery.
By Abigail Zuger, MD
November 27, 2007
Covering:
Hancock MJ et al., Lancet 2007 Nov 10; 370:1638
Koes BW., Lancet 2007 Nov 10; 370:1595
Parathyroid Hormone vs. Alendronate for Steroid-Induced Osteoporosis
General Medicine Summary and Comment
Parathyroid hormone was associated with significantly greater increases in BMD and fewer vertebral fractures — but not nonvertebral fractures.
By Allan S. Brett, MD
November 27, 2007
Covering:
Saag KG et al., N Engl J Med 2007 Nov 15; 357:2028
Does Keyboard Use Increase the Risk for Carpal Tunnel Syndrome?
General Medicine Summary and Comment
Free
This study suggested an inverse relation between use and risk, but questions remain.
Biologic Therapy Apparently More Effective Than Oral Therapy for Glucocorticoid-Associated Osteoporosis
Dermatology Summary and Comment
Teriparatide was associated with greater bone density and fewer vertebral fractures in corticosteroid recipients, but the therapy is costly.
The Importance of Knee Buckling
General Medicine Summary and Comment
Free
More than 10% of adults reported knee buckling in the past 3 months.
Protection for Those Who Have Experienced Hip Fracture
Women's Health Summary and Comment
Annual intravenous bisphosphonate therapy prevented new osteoporotic fractures.
Weight Control and Bone Density During the Menopausal Transition
General Medicine Summary and Comment
Free
A healthful diet and exercise program has a downside: loss in BMD.
By Robert W. Rebar, MD
October 30, 2007
Covering:
Park HA et al., J Clin Endocrinol Metab 2007 Oct; 92:3809
Preventing Subsequent Fractures After Hip Fracture
General Medicine Summary and Comment
Zoledronic acid was effective for secondary prevention.
By Allan S. Brett, MD
October 25, 2007
Covering:
Lyles KW et al., N Engl J Med 2007 Nov 1; 357
OC Effect on Bone Density: Still Not Clear
Women's Health Summary and Comment
Among female military cadets, oligomenorrhea and current OC use were associated with reduced BMD at certain skeletal sites.
Aromatase-Inhibitor–Induced Joint Complaints: An Underappreciated Problem?
Joint complaints are common among women who receive AIs.
Is "Chronic Lyme Disease" Real?
Dermatology Summary and Comment
Free
Patients with chronic symptoms but no objective criteria for infection are receiving long-term antibiotic therapy.
By Mary Wu Chang, MD
October 3, 2007
Covering:
Feder HM et al., N Engl J Med 2007 Oct 4; 357:1422
Joint Symptoms in Women Taking Aromatase Inhibitors for Breast Cancer
General Medicine Summary and Comment
Patients who received aromatase inhibitors commonly reported joint symptoms.
By Allan S. Brett, MD
September 27, 2007
Covering:
Crew KD et al., J Clin Oncol 2007 Sep 1; 25:3877
Raloxifene Approved for Lowering Breast Cancer Risk in Postmenopausal Women
Women's Health News in Context
Free
The FDA has approved a second SERM for breast cancer chemoprophylaxis.
By Andrew M. Kaunitz, MD
September 27, 2007
Covering:
U.S. Food and Drug Administration (FDA).,
