Maternal Obesity Increases Risk for Birth Defects
General Medicine Summary and Comment
Free
Maternal obesity and overweight increased risk for many birth defects, but obesity decreased risk for gastroschisis.
Weight Gain with Olanzapine: Does Metformin Help?
Psychiatry Summary and Comment
Free
Patients lost a little, but not enough to make a difference.
By Jonathan Silver, MD
August 27, 2007
Covering:
Baptista T et al., Schizophr Res 2007 Jul; 93:99-108
Atypical Antipsychotics: A Weighty Subject
Psychiatry Summary and Comment
Even patients taking antipsychotics for the first time gain significant weight with atypicals.
By Jonathan Silver, MD
August 27, 2007
Covering:
Strassnig M et al., Schizophr Res 2007 Jul; 93:90-8
Detection of Celiac Disease in Primary Care Practices
Gastroenterology Summary and Comment
Less than 5% of the U.S. population with celiac disease is identified and treated in primary care practices.
By Douglas K. Rex, MD
August 24, 2007
Covering:
Catassi C et al., Am J Gastroenterol 2007 Jul; 102:1454-60
Acute MI as a Marker for Diabetes Risk
Cardiology Summary and Comment
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High rates of impaired fasting glucose and diabetes after MI suggest that MI could be a prediabetes risk equivalent.
By Beat J. Meyer, MD
August 23, 2007
Covering:
Mozaffarian D et al., Lancet 2007 Aug 25; 370:667-75
Opie LH., Lancet 2007 Aug 25; 370:634-5
Western Diet and Recurrence of Colon Cancer
General Medicine Summary and Comment
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A diet of fats and sweets was associated with increased risk for recurrence.
Does Bariatric Surgery Lower Long-Term Mortality?
General Medicine Summary and Comment
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Yes, bariatric surgery in morbidly obese patients reduced long-term mortality.
By Allan S. Brett, MD
August 22, 2007
Covering:
Sjöström L et al., N Engl J Med 2007 Aug 23; 357:741-52
Adams TD et al., N Engl J Med 2007 Aug 23; 357:753-61
It’s Never Too Late to Adopt a Healthy Lifestyle
Cardiology Summary and Comment
In a cohort analysis, middle-aged people who changed their habits for the better enjoyed benefits rapidly.
By Joel M. Gore, MD
August 22, 2007
Covering:
King DE et al., Am J Med 2007 Jul; 120:598-603
Bariatric Surgery and Long-Term Mortality
Gastroenterology Summary and Comment
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Two studies showed that long-term mortality was lower among extremely obese patients who underwent bariatric surgery than among those who didn’t, but we still need trials in which aggressive medical therapy is compared with surgery for this group.
Psoriasis Is Related to Weight Gain in Women
Dermatology Summary and Comment
Another piece of the psoriasis and obesity puzzle falls into place.
By Jeffrey P. Callen, MD
August 17, 2007
Covering:
Setty AR et al., Arch Intern Med 2007 Aug 13; 167:1670-5
Children Who Supersize . . .
. . . tend to eat in fast-food restaurants or in front of the television.
Another Reason to Eat Your Vegetables: Effect on Risk for Aggressive Prostate Cancer
Cruciferous vegetable consumption was associated with lower risk for extraprostatic disease.
By Robert Dreicer, MD, MS, FACP
August 14, 2007
Covering:
Kirsh VA et al., J Natl Cancer Inst 2007 Aug 1; 99:1200-9
Obesity, Abdominal Diameter, and GERD
Gastroenterology Summary and Comment
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At least in white patients, the amount of visceral adipose tissue is related to the severity of GERD symptoms.
By David A. Johnson, MD
August 10, 2007
Covering:
El-Serag HB et al., Gut 2007 Jun; 56:749-55
Corley DA et al., Gut 2007 Jun; 56:756-62
Coffee Consumption Lowers Risk for Liver Cancer
Gastroenterology Summary and Comment
In this meta-analysis, increasing coffee consumption by two cups daily lowered HCC relative risk by 43%.
By Atif Zaman, MD, MPH
August 3, 2007
Covering:
Larsson SC and Wolk A., Gastroenterology 2007 May; 132:1740-5
Warding Off Cancer: Is It All in the D-livery?
Women's Health Summary and Comment
Women randomized to calcium plus 1000 IU of vitamin D developed fewer cancers.
By Diane E. Judge, APN/CNP
August 2, 2007
Covering:
Lappe JM et al., Am J Clin Nutr 2007 Jun; 85:1586-91
Family Therapy for Adolescents with Anorexia Nervosa
Family therapy yields positive long-term outcomes, but, in some cases, parents and adolescents should be seen separately.
By Alain Joffe, MD, MPH, FAAP
August 1, 2007
Covering:
Eisler I et al., J Child Psychol Psychiatry 2007 Jun; 48:552-60
Lactobacillus Helps Prevent Antibiotic-Related Diarrhea
General Medicine Summary and Comment
Probiotic use reduced the chances of antibiotic-related diarrhea by 75% at a reasonable cost.
By Keith I. Marton, MD
July 26, 2007
Covering:
Hickson M et al., BMJ 2007 Jul 14; 335:80
Salmonella Outbreak Linked with a Snack Food Favorite
The manufacturer of Veggie Booty has issued a voluntary recall.
By Peggy Sue Weintrub, MD
July 25, 2007
Family-Based Intervention for Childhood Obesity Shows Promise
An intensive intervention led to improvement in body composition and insulin resistance.
By F. Bruder Stapleton, MD
July 25, 2007
Covering:
Savoye M et al., JAMA 2007 Jun 27; 297:2697-704
Effect of Diet and Physical Activity on Breast Cancer Survival
Oncology and Hematology Summary and Comment
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Healthful eating and exercise were associated with lower 6-year mortality in survivors of ER-positive breast cancer.
By William J. Gradishar, MD
July 16, 2007
Covering:
Pierce JP et al., J Clin Oncol 2007 Jun 10; 25:2345-51
What Caused the Decline in Cardiac Death Rate from 1980 to 2000?
Cardiology Summary and Comment
Free
A new analysis credits improved treatment and reduction in risk factors about equally.
By Harlan M. Krumholz, MD, SM
July 11, 2007
Covering:
Ford ES et al., N Engl J Med 2007 Jun 7; 356:2388-98
Folic Acid to Prevent Recurrence of Colorectal Adenomas?
Gastroenterology Summary and Comment
A large, randomized trial showed no evidence of benefit.
By Douglas K. Rex, MD
July 6, 2007
Covering:
Cole BF et al., JAMA 2007 Jun 6; 297:2351-9
Ulrich CM and Potter JD., JAMA 2007 Jun 6; 297:2408-9
Good News and Bad News About Colonic Polyps and Prevention of Colon Cancer: The Bad News
Folic acid failed to prevent colorectal polyps and might increase risk for polyps that are more advanced.
By David H. Ilson, MD, PhD
July 2, 2007
Covering:
Cole BF et al., JAMA 2007 Jun 6; 297:2351-9
Lowering Homocysteine Does Not Reduce VTE Risk
General Medicine Summary and Comment
Vitamin therapy successfully lowered homocysteine levels, but without any effect on VTE incidence.
By Richard Saitz, MD, MPH, FACP, FASAM
June 28, 2007
Covering:
Ray JG et al., Ann Intern Med 2007 Jun 5; 146:761-7
No Easy Answer to Controlling Caloric Intake from "Super-Sized" Meals
Changing how fast food is served did not affect total calorie consumption.
By Alain Joffe, MD, MPH, FAAP
June 27, 2007
Covering:
Ebbeling CB et al., Pediatrics 2007 May; 119:869-75
