Finally, Practical Guidelines for Initiating Complementary Food in Infants
Pediatrics and Adolescent Medicine
Clinical Practice Guideline Watch
Early introduction of allergenic foods as complementary foods might actually reduce risk for food allergy.
By David J. Amrol, MD
February 20, 2013
Covering:
Fleischer DM et al., J Allergy Clin Immunol In Pract 2013 Jan; 1:29
Lifting the Taboo on Eggs
General Medicine
Summary and Comment
Meta-analysis shows little association between egg consumption and coronary heart disease or stroke.
Fever Spike? Look at the Food Tray.
Hospital Medicine
Summary and Comment
Febrile hospitalized patients with normal food intake have a low likelihood of bacteremia.
Treating ADHD Without Drugs: A Meta-Analysis
Psychiatry
Summary and Comment
Free
Supplementation with free fatty acids showed positive effects in analyses of blinded assessments, after adjustment for medication use.
By Barbara Geller, MD
February 15, 2013
Covering:
Sonuga-Barke EJS et al., Am J Psychiatry 2013 Jan 30
Perinatal Choline for Infants with a Schizophrenia Risk Gene
Psychiatry
Summary and Comment
Infants with the risk allele who received placebo had a schizophrenia endophenotype, but not infants receiving choline.
By Barbara Geller, MD
February 15, 2013
Covering:
Ross RG et al., Am J Psychiatry 2013 January 15
No CV Benefit from Vitamin and Antioxidant Supplements
General Medicine
Summary and Comment
Taking vitamins and antioxidants does not prevent major adverse cardiovascular events.
Malnutrition and the Microbiome
Infectious Diseases
Summary and Comment
A study of twin pairs in Malawi suggests that children with kwashiorkor have an altered gut microbiome.
Antibiotics Reduce Mortality in Children with Severe Malnutrition
Adding antibiotics to sound nutritional therapy improves nutritional outcomes and survival.
Early Introduction of Complementary Foods Might Prevent Allergic Disease
Duration of total breast-feeding is more important than exclusive breast-feeding for prevention of asthma and allergies.
By David J. Amrol, MD
January 30, 2013
Covering:
Nwaru BI et al., J Allergy Clin Immunol 2013 Jan; 131:78
The Effect of Milk Intake on Vitamin D and Iron Levels in Children
Dermatology
Summary and Comment
Consuming 2 cups of milk per day is sufficient to maintain healthy vitamin D levels without depleting iron levels for most children at northern latitudes.
By Mary Wu Chang, MD
January 18, 2013
Covering:
Maguire JL et al., Pediatrics 2013 Jan; 131:e144
Only Substantial Obesity Is Associated with All-Cause Mortality
General Medicine
Summary and Comment
Free
In a meta-analysis, being modestly overweight was somewhat protective.
By Thomas L. Schwenk, MD
January 17, 2013
Covering:
Flegal KM et al., JAMA 2013 Jan 2; 309:71
Heymsfield SB and Cefalu WT., JAMA 2013 Jan 2; 309:87
Fructose and Glucose Ingestion Affect Appetite Pathways in the Brain Differently
General Medicine
Summary and Comment
Fructose also resulted in lower peak levels of satiety hormones.
Nonceliac IBS Might Be "Wheat Sensitivity"
General Medicine
Summary and Comment
Free
Some patients with irritable bowel syndrome but without celiac disease improved on a wheat-free diet.
By David J. Amrol, MD
January 10, 2013
Covering:
Carroccio A et al., Am J Gastroenterol 2012 Dec; 107:1898
Sanders DS and Aziz I., Am J Gastroenterol 2012 Dec; 107:1908
Folate for Treatment-Resistant Depression
Psychiatry
Summary and Comment
Supplementing SSRIs with the biologically available form of folate increases response but not remission rates.
By Joel Yager, MD
January 7, 2013
Covering:
Papakostas GI et al., Am J Psychiatry 2012 Dec 1; 169:1267
Nelson JC., Am J Psychiatry 2012 Dec 1; 169:1223
Risk and Adverse Effects of Energy Drink Consumption
General Medicine
Summary and Comment
Risks are particularly elevated when heavily caffeinated drinks are mixed with alcohol.
By Thomas L. Schwenk, MD
January 3, 2013
Covering:
Sepkowitz KA., JAMA 2012 Dec 19
Howland J and Rohsenow DJ., JAMA 2012 Dec 19
Short-Term Correction of Vitamin D Deficiency in Healthy Young Women
General Medicine
Summary and Comment
Supplementation raised 25-hydroxyvitamin D levels substantially, but with no physical benefits.
By Allan S. Brett, MD
January 3, 2013
Covering:
Goswami R et al., J Clin Endocrinol Metab 2012 Dec; 97:4709
Low Total-Fat Intake Is Associated with Lower Weight, Body-Mass Index, and Waist Circumference
General Medicine
Summary and Comment
A meta-analysis backs up observations about fat intake.
Are Organic Foods Really Better for Kids?
The American Academy of Pediatrics Committee on Nutrition and Council on Environmental Health review the evidence and lack thereof.
Fish Consumption Is Associated with Lower Cerebrovascular Risk
General Medicine
Summary and Comment
But supplementation with long-chain -3 fatty acids was not.
No Benefit of Multivitamins for Preventing Cardiovascular Disease in Men
General Medicine
Summary and Comment
Free
A randomized, controlled trial showed that myocardial infarction, stroke, and death were not affected.
Higher Calcium Intake Is Associated with Lower Risk for Primary Hyperparathyroidism
General Medicine
Summary and Comment
In a large cohort, higher dietary calcium intake and supplementation both lowered risk.
Feeding Tubes in Patients with Advanced Dementia
General Medicine
Summary and Comment
Tube feedings did not extend life in a nursing home cohort.
By Allan S. Brett, MD
October 30, 2012
Covering:
Teno JM et al., J Am Geriatr Soc 2012 Oct; 60:1918
Zonisamide Can Augment Weight Loss
General Medicine
Summary and Comment
But in a randomized trial, incremental benefit was modest and adverse effects were common.
Overweight and Obese Children Have Excess CV Risk
General Medicine
Summary and Comment
Meta-analysis reveals associations between high body-mass index and multiple adverse cardiovascular risk factors.
Prenatal Mercury Exposure, Fish Consumption, and ADHD Symptoms
Prenatal mercury exposure increases risk for attention-deficit/hyperactivity disorder symptoms in children, while prenatal fish consumption decreases risk.
By Cornelius W. Van Niel, MD
October 24, 2012
Covering:
Sagiv SK et al., Arch Pediatr Adolesc Med 2012 Oct 8
Lanphear BP., Arch Pediatr Adolesc Med 2012 Oct 8