BMI and Mortality: A Study in Korea
Cardiology
Summary and Comment
Researchers found an association between being overweight and increased all-cause mortality risk, but not in people older than 65.
By Harlan M. Krumholz, MD, SM
September 20, 2006
Covering:
Jee SH et al., N Engl J Med 2006 Aug 24; 355:779-87
An Obesity Paradox in CAD Patients
Cardiology
Summary and Comment
A meta-analysis casts doubt on high BMI as a mortality predictor, at least in patients with established heart disease.
By Harlan M. Krumholz, MD, SM
September 20, 2006
Covering:
Romero-Corral A et al., Lancet 2006 Aug 19; 368:666-78
Franzosi MG., Lancet 2006 Aug 19; 368:624-5
Calorie Underestimation
Cardiology
Summary and Comment
The bigger a meal is, the more likely someone is to underestimate its calorie content, regardless of the persons body size.
By Joel M. Gore, MD
September 20, 2006
Covering:
Wansink B and Chandon P., Ann Intern Med 2006 Sep 5; 145:326-32
Orlistat for Patients with Nonalcoholic Fatty Liver Disease
Gastroenterology
Summary and Comment
Orlistat in conjunction with a weight-loss program, compared with a weight-loss program alone, can significantly reduce NAFLD.
By Atif Zaman, MD, MPH
September 8, 2006
Covering:
Zelber-Sagi S et al., Clin Gastroenterol Hepatol 2006 May; 4:639-44
Matters of the Heart Are Weighty
Women's Health
Summary and Comment
Extremely obese women face high rates of coronary heart disease and death.
By Marian C. Limacher, MD
September 7, 2006
Covering:
McTigue K et al., JAMA 2006 Jul 5; 296:79-86
Body-Mass Index and Mortality in the U.S.
General Medicine
Summary and Comment
Free
Being overweight increases risk for mortality among middle-aged nonsmokers.
By Allan S. Brett, MD
August 23, 2006
Covering:
Adams KF et al., N Engl J Med 2006 Aug 24; 355:763-78
Mortality May Be Improving in Patients Hospitalized for Anorexia Nervosa
Psychiatry
Summary and Comment
Free
Why? Is it better treatment or earlier detection?
By Joel Yager, MD
August 21, 2006
Covering:
Lindblad F et al., Am J Psychiatry 2006 Aug; 163:1433-5
Laparoscopic Gastric Banding for Treating Mild-to-Moderate Obesity
Gastroenterology
Summary and Comment
Surgical therapy was more effective than nonsurgical therapy in reducing weight and improving quality of life.
By Stuart Sherman, MD
August 18, 2006
Covering:
O’Brien PE et al., Ann Intern Med 2006 May 2; 144:625-33
Wadden TA and Tsai AG., Ann Intern Med 2006 May 2; 144:689-91
Sibutramine for Obese Adolescents
General Medicine
Summary and Comment
Free
Sibutramine, compared with placebo, led to substantial weight loss.
By Richard Saitz, MD, MPH, FACP, FASAM
August 17, 2006
Covering:
Berkowitz RI et al., Ann Intern Med 2006 Jul 18; 145:81-90
Dietz WH., Ann Intern Med 2006 Jul 18; 145:145-6
Overweight in Adolescence and Mortality in Women
General Medicine
Summary and Comment
Excess pounds as a teen can shorten lifespan.
By Richard Saitz, MD, MPH, FACP, FASAM
August 17, 2006
Covering:
van Dam RM et al., Ann Intern Med 2006 Jul 18; 145:91-7
Can Seafood Consumption Help Reduce Childhood Depression?
Significantly more depressed children who received omega-3 fatty acids achieved remission than those who received placebo.
By Martin T. Stein, MD
August 16, 2006
Covering:
Nemets H et al., Am J Psychiatry 2006 Jun; 163:1098-100
Parker G et al., Am J Psychiatry 2006 Jun; 163:969-78
Neurologic Complications of Bariatric Surgery
Neurology
Summary and Comment
Free
Neurologic complications, due primarily to nutritional deficiencies, are common and necessitate ongoing and thorough patient follow-up.
By Elliott L. Mancall, MD
August 15, 2006
Covering:
Koffman BM et al., Muscle Nerve 2006 Feb; 33:166-76
Bariatric Surgery for Super Morbidly Obese Patients
General Medicine
Summary and Comment
Better long-term outcomes were reported after gastric bypass than after adjustable banding.
By Allan S. Brett, MD
August 10, 2006
Covering:
Bowne WB et al., Arch Surg 2006 Jul; 141:683-9
Obesity Increases Risk for Chronic Kidney Failure
The risk probably starts to accumulate before age 20.
By F. Bruder Stapleton, MD
August 9, 2006
Covering:
Ejerblad E et al., J Am Soc Nephrol 2006 Jun; 17:1695-702
Chertow GM et al., J Am Soc Nephrol 2006 Jun; 17:1501-2
Prevalence of Obesity Surgery and Its Complications
General Medicine
Summary and Comment
The prevalence has increased dramatically, and complications may be more common than previously reported.
By Allan S. Brett, MD
August 8, 2006
Covering:
Smoot TM et al., Am J Public Health 2006 Jul; 96:1187-9
Encinosa WE et al., Med Care 2006 Aug; 44:706-12
Are Nutritional Interventions Effective in Cancer Patients?
General Medicine
Summary and Comment
For now, we have little evidence that nutritional interventions are effective in patients with cancer or preinvasive neoplasia.
By Allan S. Brett, MD
August 3, 2006
Covering:
Davies AA et al., J Natl Cancer Inst 2006 Jul 19; 98:961-73
Mediterranean Diets vs. Low-Fat Diet
General Medicine
Summary and Comment
Cardiovascular risk factors improved more on the Mediterranean diet.
By Richard Saitz, MD, MPH, FACP, FASAM
August 3, 2006
Covering:
Estruch R et al., Ann Intern Med 2006 Jul 4; 145:1-11
Mediterranean vs. Low-Fat Diet
Cardiology
Summary and Comment
These two types of diets were compared in a short-term trial involving asymptomatic patients at high risk for cardiovascular disease.
By Joel M. Gore, MD
August 2, 2006
Covering:
Estruch R et al. for the PREDIMED Study Investigators., Ann Intern Med 2006 Jul 4; 145:1-11
Extreme Obesity in Women
Cardiology
Summary and Comment
WHI data highlight the importance of the degree of obesity, not just obesity itself, in assessing mortality risk.
By JoAnne M. Foody, MD
August 2, 2006
Covering:
McTigue K et al., JAMA 2006 Jul 5; 296:79-86
Body Weight and Acute Biliary Pancreatitis
Gastroenterology
Summary and Comment
The more patients weigh, the more severe their disease is likely to be.
By Stuart Sherman, MD
July 28, 2006
Covering:
De Waele B et al., Pancreas 2006 May; 32:343-5
Tying Television Viewing to Activity in Obese Children
It works, but can parents and children live with earned "screen time"?
By Howard Bauchner, MD
July 26, 2006
Covering:
Goldfield GS et al., Pediatrics 2006 Jul; 118:e157-66
Vitamins C and E and the Risk for Preeclampsia and Perinatal Complications
Women's Health
Summary and Comment
Neither mothers, nor their infants, benefited from maternal vitamin C and E supplementation during pregnancy.
By Sandra Ann Carson, MD
July 20, 2006
Covering:
Rumbold AR et al., N Engl J Med 2006 Apr 27; 354:1796-806
Adolescent Obesity and Structural Changes in the Heart
General Medicine
Summary and Comment
These data suggest that frank obesity, even in adolescents, is associated not only with compensatory hypertrophy for higher hemodynamic workload but also with other structural changes.
By Kirsten E. Fleischmann, MD, MPH
July 20, 2006
Covering:
Chinali M et al., J Am Coll Cardiol 2006 Jun 6; 47:2267-73
von Haehling S et al., J Am Coll Cardiol 2006 Jun 6; 47:2274-6
Tying Television Viewing to Activity in Obese Children
General Medicine
Summary and Comment
It works, but can parents and children live with earned "screen time"?
By Howard Bauchner, MD
July 18, 2006
Covering:
Goldfield GS et al., Pediatrics 2006 Jul; 118:e157-66
Inflammatory Cytokines and the Metabolic Syndrome: Animal Clues
Psychiatry
Summary and Comment
New directions for studying a syndrome of relevance to psychiatric patients
By Steven Dubovsky, MD
July 17, 2006
Covering:
Netea MG et al., Nat Med 2006 Jul; 12:650-6