Both Fish Oil and Fibrates Reduce Triglyceride Levels
HIV/AIDS Summary and Comment
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Both fish oil and fenofibrate safely reduce elevated triglyceride levels in HIV-infected patients receiving ART.
By Keith Henry, MD
April 28, 2008
Covering:
Gerber JG et al., J Acquir Immune Defic Syndr 2008 Apr 1; 47:459
How Low Should We Go (with BP and Cholesterol in Diabetic Patients)?
General Medicine Summary and Comment
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Lower might be better, but more clinical data are needed.
Diminishing the Flush of Niacin
Cardiology Summary and Comment
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Results of a small study suggest that adding a prostaglandin D2 antagonist may render niacin more tolerable for treating lipid disorders in many patients.
By Joel M. Gore, MD
April 23, 2008
Covering:
Paolini JF et al., Am J Cardiol 2008 Mar 1; 101:625
Warfarin Increases Delayed Bleeding After Skin Surgery
Dermatology Summary and Comment
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But there is no need to stop warfarin if careful management is employed.
By George J. Hruza, MD
April 18, 2008
Covering:
Blasdale C and Lawrence CM., Br J Dermatol 2008 Mar; 158:522
Aggressive Treatment of High LDL Levels and Hypertension in Patients with Diabetes
Cardiology Summary and Comment
Free
Three-year results from SANDS supply much-needed information but no definitive answer to the question of how low to set targets in primary prevention of CVD.
Patterns of Ezetimibe Use in the U.S. and Canada
Cardiology Summary and Comment
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A distinct difference in prescribing practices between the two countries raises questions about what influences clinical decision making.
Effects of Statins and ACE Inhibitors in CAP and Influenza
Infectious Diseases Summary and Comment
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An analysis of VA data indicates that, at least in men, statin or ACE inhibitor use is associated with decreased mortality from community-acquired pneumonia or influenza.
By Thomas Glück, MD
April 2, 2008
Covering:
Mortensen EM et al., Eur Respir J 2008 Mar; 31:611
Vytorin Fails to Improve Carotid Intima–Media Thickness
General Medicine Summary and Comment
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Despite lower LDL cholesterol levels with Vytorin, no clinical benefits were noted.
By Allan S. Brett, MD
April 1, 2008
Covering:
Kastelein JJP et al., N Engl J Med 2008 Apr 3; 358:1504
Pioglitazone vs. Glimepiride for Atherosclerosis in Diabetes
Cardiology Summary and Comment
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Pioglitazone comes out on top in this randomized trial, but we still need outcomes data.
By Harlan M. Krumholz, MD, SM
March 31, 2008
Covering:
Nissen SE et al. for the PERISCOPE Investigators., JAMA 2008 Apr 2; 299:1561
Does Ezetimibe ENHANCE the Benefits of Statins?
Cardiology Summary and Comment
Free
Perhaps not, suggest these findings from a study of combination therapy’s effect on carotid-artery intima–media thickness
By Harlan M. Krumholz, MD, SM
March 30, 2008
Covering:
Kastelein JJP et al. for the ENHANCE investigators., N Engl J Med 2008 Apr 3; 358:1431
Brown BG and Taylor AJ., N Engl J Med 2008 Apr 3; 358:1504
Drazen JM et al., N Engl J Med 2008 Apr 3; 358:1507
