Chronic Hypertension Associated with Fetal Growth Restriction
General Medicine Summary and Comment
Analysis of a large longitudinal sample of pregnancies showed that chronic hypertension raised risk for small-for-gestational-age births in both term and preterm pregnancies.
By Robert W. Rebar, MD
September 30, 2008
Covering:
Catov JM et al., Obstet Gynecol 2008 Aug; 112:290
Telmisartan in ACE-Inhibitor–Intolerant Patients: A Disappointment
Cardiology Summary and Comment
In a placebo-controlled trial, researchers found an unexpectedly low, statistically nonsignificant reduction in clinical outcomes.
By Beat J. Meyer, MD
September 17, 2008
Covering:
The TRANSCEND Investigators., Lancet 2008 August 31
Should β-Blockers Be Continued for Patients Hospitalized with Heart Failure?
General Medicine Summary and Comment
Continuation of β-blockers was associated with better outcomes than was discontinuation.
How Fat Am I? Or, How Am I Fat?
Cardiology Summary and Comment
Two new studies address how obesity relates to cardiovascular risk factors.
By JoAnne M. Foody, MD
September 3, 2008
Covering:
Wildman RP et al., Arch Intern Med 2008 Aug 11; 168:1617
Stefan N et al., Arch Intern Med 2008 Aug 11; 168:1609
Preventing Stroke Recurrence: How Best to Control Hypertension?
Cardiology Summary and Comment
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In a randomized trial, use of an ARB to lower blood pressure in patients with recent stroke did not improve outcomes.
Renin-Angiotensin Inhibition for Renoprotection in Patients at High Cardiovascular Risk
Cardiology Summary and Comment
Monotherapy with an ACE inhibitor or an ARB improved major renal outcomes, but combination therapy worsened them, despite a greater reduction in proteinuria.
By Beat J. Meyer, MD
August 27, 2008
Covering:
Mann JFE et al., Lancet 2008 Aug 16; 372:547
Prehypertension and Hypertension in Adolescents
An estimated 7% of prehypertensive adolescents develop hypertension annually.
By Howard Bauchner, MD
August 13, 2008
Covering:
Falkner B et al., Pediatrics 2008 Aug; 122:238
White-Coat Hypertension: A Caution
Findings of a small study suggest that left ventricular mass index is higher in children with white-coat hypertension than in those with normal blood pressure.
USPSTF Recommends Screening for Diabetes in Adults with Elevated Blood Pressure
General Medicine Clinical Practice Guideline Watch
Evidence was insufficient to recommend screening of asymptomatic people with lower blood pressure.
By Richard Saitz, MD, MPH, FACP, FASAM
July 24, 2008
Covering:
Norris SL et al., Ann Intern Med 2008 Jun 3; 148:855
U.S. Preventive Services Task Force., Ann Intern Med 2008 Jun 3; 148:846
Primary Hyperaldosteronism: Rare, but Important to Diagnose and Treat
General Medicine Summary and Comment
If roughly 10% of hypertension cases are resistant to treatment, and, if primary hyperaldosteronism accounts for about 10% of those cases, then the overall prevalence would be around 1%.
By Bruce Soloway, MD
July 23, 2008
Covering:
Douma S et al., Lancet 2008 Jun 7; 371:1921
Kaplan NM., Lancet 2008 Jun 7; 371:1890
