Can Progesterone Prevent Preterm Birth?
General Medicine
Summary and Comment
Free
Progesterone shows promise, but its uncertain when it is most beneficial.
By Robert W. Rebar, MD
August 1, 2007
Covering:
Rouse DJ et al., N Engl J Med 2007 Aug 2; 357:454-61
Fonseca EB et al., N Engl J Med 2007 Aug 2; 357:462-9
Thornton JG., N Engl J Med 2007 Aug 2; 357:499-501
Simhan HN and Caritis SN., N Engl J Med 2007 Aug 2; 357:477-87
Cervical Cancer Screening: Use a Computer to Find More Abnormal Cells
Women's Health
Summary and Comment
A computerized system for reading cytology slides detected more cases of high-grade squamous disease than manually read conventional cytology slides.
By Wendy S. Biggs, MD
July 26, 2007
Covering:
Davey E et al., BMJ 2007 Jul 7; 335:31
A Second HPV Vaccine May Also Prevent Cervical Cancer
General Medicine
Summary and Comment
In an interim analysis, the bivalent vaccine showed 90% efficacy for preventing CIN2+ associated with HPV 16 or 18.
By Bruce Soloway, MD
July 24, 2007
Covering:
Paavonen J et al., Lancet 2007 Jun 30; 369:2161-70
Autologous Adult Stem-Cell Therapy for Treating Stress Incontinence
General Medicine
Summary and Comment
This technique, although effective, requires more study before widespread use.
By Anthony L. Komaroff, MD
July 19, 2007
Covering:
Strasser H et al., Lancet 2007 Jun 30; 369:2179-86
Novara G and Artibani W., Lancet 2007 Jun 30; 369:2139-40
Estrogen Therapy and Coronary Calcification
Cardiology
Summary and Comment
Free
More evidence that estrogen therapy early in menopause may confer more benefit than risk
By Harlan M. Krumholz, MD, SM
July 18, 2007
Covering:
Manson JE et al. for the WHI and WHI-CACS Investigators., N Engl J Med 2007 Jun 21; 356:2591-602
Maternal Asymptomatic Group B Strep Bacteriuria Can Lead to Chorioamnionitis
General Medicine
Summary and Comment
Early treatment with antibiotics may reduce transmission of this devastating infection to newborns.
By Robert W. Rebar, MD
July 3, 2007
Covering:
Anderson BL et al., Am J Obstet Gynecol 2007 Jun; 196:524.e1-5
Might Treating Asymptomatic Bacterial Vaginosis Prevent Sexually Transmitted Infections?
General Medicine
Summary and Comment
Treatment and prophylaxis resulted in significantly fewer new cases of chlamydia.
By Robert W. Rebar, MD
July 3, 2007
Covering:
Schwebke JR and Desmond R., Am J Obstet Gynecol 2007 Jun; 196:517.e1-6
Predicting the Final Menstrual Period
Women's Health
Summary and Comment
Free
Can it be done?
By Diane E. Judge, APN/CNP
June 21, 2007
Covering:
Santoro N et al., Menopause 2007 May/Jun; 14:415-24
Is Liquid-Based Cervical Cytology Better Than Conventional?
General Medicine
Summary and Comment
No improvement was found in detecting grade 2 or 3 cervical intraepithelial neoplasia.
By Robert W. Rebar, MD
June 12, 2007
Covering:
Ronco G et al., BMJ 2007 May 21
Treating Vaginal Atrophy with Local Estrogen
Women's Health
Practice Watch
Free
NAMS guidelines state that therapy choice should be individualized based on clinical experience and patient preference.
By Diane E. Judge, APN/CNP
June 7, 2007
Covering:
Menopause 2007 May/Jun; 14:370-1
Is an Intact Uterus Necessary for Good Sex?
Women's Health
Summary and Comment
Hysterectomy for menorrhagia did not compromise sexual satisfaction.
By Sandra Ann Carson, MD
June 7, 2007
Covering:
Halmesmäki K et al., BJOG 2007 May; 114:563-8
HPV Vaccine Prevents Precancerous Vulvovaginal Lesions
General Medicine
Summary and Comment
No women who completed the full vaccine protocol developed lesions related to an HPV type to which they were previously susceptible.
By Bruce Soloway, MD
May 31, 2007
Covering:
Joura EA et al., Lancet 2007 May 19; 369:1693-702
Treatment of Urinary Stress Incontinence Which Surgery Is Best?
Women's Health
Summary and Comment
Fascial sling had a higher success rate but greater morbidity than Burch colposuspension.
By Andrew M. Kaunitz, MD
May 24, 2007
Covering:
Albo ME et al., N Engl J Med 2007 May 24; 356:2143-55
Strohbehn K., N Engl J Med 2007 May 24; 356:2198-200
When Confidentiality Concerns Interfere with Teens Seeking Healthcare
Teens who forgo healthcare because of concerns about confidentiality are high risk and in need of services.
By M. Susan Jay, MD
May 16, 2007
Covering:
Lehrer JA et al., J Adolesc Health 2007 Mar; 40:218-26
Postmenopausal Pelvic Organ Prolapse Waxes and Wanes
General Medicine
Summary and Comment
Mild prolapse appears unlikely to progress significantly in the short term.
By Robert W. Rebar, MD
May 10, 2007
Covering:
Bradley CS et al., Obstet Gynecol 2007 Apr; 109:848-54
Cervical Surgerys Effect on Delivery Outcome
Women's Health
Summary and Comment
Free
Surgical treatment of CIN increased the risk for preterm delivery.
By Ann J. Davis, MD
May 10, 2007
Covering:
Jakobsson M et al., Obstet Gynecol 2007 Feb; 109:309-13
The HPV Vaccine and Cervical Neoplasia: Not Just for Warts Anymore
Dermatology
Summary and Comment
Free
Widespread immunization against HPV will reduce rates of both cervical cancer and genital warts.
By Craig A. Elmets, MD
May 9, 2007
Covering:
The FUTURE II Study Group., N Engl J Med 2007 May 10; 356:1915-27
More Than an Ounce of Prevention for HPV
Dermatology
Summary and Comment
A safe and effective HPV vaccine means reduced risk for associated disease now and a hope for future vaccines.
By Craig A. Elmets, MD
May 9, 2007
Covering:
Garland SM et al., N Engl J Med 2007 May 10; 356:1928-43
Efficacy and Safety of the Quadrivalent HPV Vaccine
Infectious Diseases
Summary and Comment
Free
Two randomized controlled trials provide an additional year of follow-up.
By Richard T. Ellison III, MD
May 9, 2007
Covering:
Garland SM et al., N Engl J Med 2007 May 10; 356:1928-43
The FUTURE II Study Group., N Engl J Med 2007 May 10; 356:1915-27
Sawaya GF and Smith-McCune K., N Engl J Med 2007 May 10; 356:1991-3
HPV-16 and Oropharyngeal Cancer
Infectious Diseases
Summary and Comment
Free
HPV-16 infection was shown to be an independent risk factor for oropharyngeal squamous-cell carcinoma.
By Richard T. Ellison III, MD
May 9, 2007
Covering:
D’Souza G et al., N Engl J Med 2007 May 10; 356:1944-56
Ovarian Cancer Treatment: Predictors of Comprehensive Surgery
Women's Health
Summary and Comment
Free
Patient, surgeon, and hospital characteristics were associated with receiving comprehensive surgery.
By Andrew M. Kaunitz MD
May 3, 2007
Covering:
Goff BA et al., Cancer 2007 Apr 9; 109:2031-42
Do Ovarian Cancer Outcomes Vary by Type of Specialist Providing Chemotherapy?
Women's Health
Summary and Comment
Gynecologic and medical oncologists employed different approaches to chemotherapy, but ovarian cancer survival was nearly identical.
By Andrew M. Kaunitz, MD
May 3, 2007
Covering:
Silber JH et al., J Clin Oncol 2007 Apr 1; 25:1169-75
The Stress of War Is Associated with Menstrual Irregularity
General Medicine
Summary and Comment
Many Lebanese civilian women living in a war zone reported changes in menstrual cycles for months after the end of a short war.
By Robert W. Rebar, MD
May 1, 2007
Covering:
Hannoun AB et al., Obstet Gynecol 2007 Apr; 109:929-32
NAMS Statement on Peri- and Postmenopausal Estrogen and Progestogen Use
Women's Health
Practice Watch
The advisory panel concluded that evidence supports the appropriate use of hormone therapy in peri- and postmenopausal women.
By Diane E. Judge, APN/CNP
April 26, 2007
Covering:
Menopause 2007 Mar/Apr; 14:168-82
Excitotoxicity Implicated in a Newly Identified Paraneoplastic Encephalomyelitis
Neurology
Summary and Comment
Onconeural anti-NMDA receptor antibodies are found in a potentially fatal, but treatment-responsive, paraneoplastic encephalomyelitis in young women with teratomas.
By John W. Henson, MD
April 24, 2007
Covering:
Dalmau J et al., Ann Neurol 2007 Jan; 61:25-36