Vaginal Estrogen Relieves Postmenopausal Vaginal Symptoms
Women's Health
Summary and Comment
Three different regimens of vaginal estrogen were better than placebo at relieving women's most bothersome symptoms, primarily vaginal dryness and dyspareunia.
By Diane E. Judge, APN/CNP
September 3, 2009
Covering:
Bachmann G et al., Menopause 2009 Jul/Aug; 16:719
Freedman M et al., Menopause 2009 Jul/Aug; 16:735
Ovarian Status and Risk for Lung Cancer
Women's Health
Summary and Comment
Further evidence that functional ovaries protect against lung cancer
Salivary Testosterone Levels Do Not Reflect Serum Levels in Postmenopausal Women
Women's Health
Summary and Comment
Poor correlation does not support routine measurement of salivary testosterone.
By Robert W. Rebar, MD
August 13, 2009
Covering:
Flyckt RL et al., Menopause 2009 Jul/Aug; 16:680
The Other Shoe Drops: New WHI Analysis
Women's Health
Summary and Comment
Free
Unfavorable balance of risks and benefits also applies to women who initiated HT within 5 years after menopause.
By Diane E. Judge, APN/CNP
August 6, 2009
Covering:
Prentice RL et al., Am J Epidemiol 2009 Jul 1; 170:12
Banks E and Canfell K., Am J Epidemiol 2009 Jul 1; 170:24
Does Hormonal Contraception Accelerate HIV Progression?
Women's Health
Summary and Comment
Use of either DMPA or OCPs was associated with hastened unfavorable disease outcomes.
By Anna Wald, MD, MPH
July 30, 2009
Covering:
Stringer EM et al., AIDS 2009 Jul 17; 23:1377
STIs in Children When Sexual Abuse Is Suspected
Comprehensive testing is important in such children. Nucleic acid amplification tests on urine specimens were more sensitive than culture for detecting <$EMPH_O>C. trachomatis<$EMPH_C> and <$EMPH_O>N. gonorrhoeae.<$EMPH_C>
By Howard Bauchner, MD
July 29, 2009
Covering:
Girardet RG et al., Pediatrics 2009 Jul; 124:79
Black CM et al., Pediatr Infect Dis J 2009 Jul; 28:608
New Emergency Contraception Developments
Women's Health
News in Context
Free
One-dose formulation is approved; two-dose formulation goes generic.
By Diane E. Judge, APN/CNP
July 23, 2009
Covering:
North Wales, PA: Teva Pharmaceuticals, Inc. 2009 Jul 10
Budapest, Hungary: Gedeon Richter, Ltd., for Duramed Pharmaceuticals, Inc. 2009
Silver Spring, MD: Food and Drug Administration 2009 Jun 24
Early Menopause, Excess Weight Dramatically Raise Endometrial Cancer Risk
Women's Health
Summary and Comment
Overweight and obese women who enter menopause before age 45 have 6-fold and 20-fold excess risk for endometrial cancer, respectively.
By Wendy S. Biggs, MD
July 23, 2009
Covering:
Thomas CC et al., Obstet Gynecol 2009 Jul; 114:22
Increasing Chlamydia Screening Rates in Adolescent Girls
By redesigning work flow during urgent care visits, physicians can increase chlamydia screening rates among sexually active teens.
By Robin Drucker, MD
July 22, 2009
Covering:
Tebb KP et al., Arch Pediatr Adolesc Med 2009 Jun; 163:559
Evidence of Polycystic Ovary Syndrome Before Onset of Puberty
Many daughters of mothers with PCOS have increased ovarian volume and metabolic abnormalities before puberty.
Menopausal HT and Ovarian Cancer: Causal Role Remains Unclear
Women's Health
Summary and Comment
Free
A Danish prospective cohort study showed HT use was associated with modest excess risk.
Diagnosis and Management of von Willebrand Disease and Other Bleeding Disorders in Women
Women's Health
Practice Watch
Free
Bleeding disorders are important causes of heavy menstrual bleeding and postpartum hemorrhage.
By Ann J. Davis, MD
July 9, 2009
Covering:
James AH et al., Am J Obstet Gynecol 2009 Jul; 201:e1
At Puberty, Daughters of Women with PCOS Differ from Daughters of Normal Women
Women's Health
Summary and Comment
PCOS daughters tended to have greater ovarian volume and hyperinsulinemia in glucose tolerance tests.
By Robert W. Rebar, MD
July 9, 2009
Covering:
Sir-Petermann T et al., J Clin Endocrinol Metab 2009 Jun; 94:1923
Extending the Age Range for HPV Vaccination? Dont Faint
Women's Health
Summary and Comment
Quadrivalent HPV vaccine was effective in HPV-naive women, aged 24–45; FDA strengthens syncope warning.
By Anna Wald, MD, MPH
July 9, 2009
Covering:
Muñoz N et al., Lancet 2009 Jun 6; 373:1949
U.S. Food and Drug Administration (FDA)., 2009 Jun 18
Enhancing the Safety of Medical Abortion
Women's Health
Summary and Comment
Free
Buccal administration of misoprostol and routine antibiotic use were associated with lower rates of serious infections after medical abortions.
The Search Continues for Effective Nonhormonal Therapies for Hot Flashes
General Medicine
Summary and Comment
Acupuncture and a Chinese herbal combination resulted in modest reductions in hot flash frequency.
By Robert W. Rebar, MD
June 25, 2009
Covering:
Borud EK et al., Menopause 2009 May/Jun; 16:484
Soares CN., Menopause 2009 May/Jun; 16:434
Grady D et al., Menopause 2009 May/Jun; 16:458
Kaunitz AM., Menopause 2009 May/Jun; 16:428
Should Women Stop HT Temporarily Before Undergoing Screening Mammography?
Women's Health
Summary and Comment
Free
Suspending HT for 1 or 2 months did not lower mammography recall rates, but did increase likelihood of experiencing vasomotor symptoms.
Is Radical Hysterectomy for Cervical Cancer Patients Obsolete?
Women's Health
Summary and Comment
Embryologically based surgical approach might offer benefits in the treatment of women with early invasive cervical cancer.
Cervical Cancer Risk Among Women Who Have Been Treated for CIN
Women's Health
Summary and Comment
Long-term risk for invasive cancer remained higher among women treated for CIN, especially those who underwent cryotherapy.
By Ann J. Davis, MD
June 25, 2009
Covering:
Melnikow J et al., J Natl Cancer Inst 2009 May 20; 101:721
Still Looking for Effective Nonhormonal Hot Flash Therapies
Women's Health
Summary and Comment
Acupuncture, Chinese herbs, and other nonestrogenic therapies resulted in modest improvements in hot flash frequency; head-to-head comparisons with estrogen are lacking.
By Robert W. Rebar, MD
June 25, 2009
Covering:
Borud EK et al., Menopause 2009 May/Jun; 16:484
Soares CN., Menopause 2009 May/Jun; 16:434
Grady D et al., Menopause 2009 May/Jun; 16:458
Kaunitz AM., Menopause 2009 May/Jun; 16:428
Bardia A et al., Menopause 2009 May/Jun; 16:477
Santoro NF and Dicken CL., Menopause 2009 May/Jun; 16:432
Patient Satisfaction 10 Years After Endometrial Ablation
Women's Health
Summary and Comment
Free
More than 75% of respondents were contented with their outcomes.
Perimenopause and Cognitive Function
Women's Health
Summary and Comment
Perimenopause is associated with declines in cognitive function; early (but not late) initiation of HT improves cognitive performance.
Hot Flashes That Just Keep Going and Going ...
Women's Health
Summary and Comment
Mean duration of vasomotor symptoms was 5.5 years in women who were followed for 13 years.
Continuous Oral Contraception and Etonogestrel Implants
Women's Health
Summary and Comment
Reassuring results about return to fertility and long-term efficacy
By Robert W. Rebar, MD
June 11, 2009
Covering:
Barnhart K et al., Fertil Steril 2009 May; 91:1654
Darney P et al., Fertil Steril 2009 May; 91:1646
Oral Raloxifene, Transdermal Estradiol Similar at Preserving Bone Density
Women's Health
Summary and Comment
Postmenopausal users of these two drugs had similarly high rates of bone density preservation and few serious side effects.