Continuous vs. Sequential Estrogen-Progestin HT and Risk for Endometrial Cancer
Women's Health
Summary and Comment
Finnish national study results show that continuous use is safer than sequential use.
By Andrew M. Kaunitz, MD
December 17, 2009
Covering:
Jaakkola S et al., Obstet Gynecol 2009 Dec; 114:1197
To Pap or Not to Pap?
Women's Health
Summary and Comment
Survey results suggest Pap test recommendations are not followed routinely in U.S. practices.
By Ann J. Davis, MD
December 17, 2009
Covering:
Yabroff KR et al., Ann Intern Med 2009 Nov 3; 151:602
Do Oral Contraceptives Explain the "Edge," as Women Overtake Men in SCC Risk?
Dermatology
Summary and Comment
The data are insufficient to draw any conclusions about current use of oral contraceptives.
By June Robinson, MD
December 11, 2009
Covering:
Applebaum KM et al., J Invest Dermatol 2009 Dec; 129:2760
Metabolic Syndrome in Male Relatives of Women with Polycystic Ovary Syndrome
Women's Health
Summary and Comment
Obesity accounts for high prevalence of metabolic syndrome in fathers and brothers of women with polycystic ovary syndrome.
By Robert W. Rebar, MD
December 10, 2009
Covering:
Coviello AD et al., J Clin Endocrinol Metab 2009 Nov; 94:4361
Are Cervical Glandular Changes on Pap Tests Linked to HIV Infection?
Women's Health
Summary and Comment
Declining CD4 counts were associated with higher risk for glandular abnormalities.
By Ann J. Davis, MD
December 3, 2009
Covering:
Massad LS et al., Obstet Gynecol 2009 Nov; 114:1063
Major Changes in ACOG Cervical Cytology Screening Recommendations
Women's Health
Clinical Practice Guideline Watch
Free
New guidelines recommend less-frequent screening that begins at age 21 regardless of age at onset of sexual activity.
By Ann J. Davis, MD
November 23, 2009
Covering:
ACOG Committee on Practice Bulletins — Gynecology., 2009 Dec; 114:1409
Is HPV Vaccination Cost-Effective for Women Older Than 30?
General Medicine
Summary and Comment
A simulation model suggests not.
Breast Tenderness After Starting Menopausal HT: An Ominous Sign?
Women's Health
Summary and Comment
In the WHI trial, HT users with new-onset breast tenderness had higher risk for breast cancer than did HT users without this side effect.
By Andrew M. Kaunitz, MD
November 19, 2009
Covering:
Crandall CJ et al., Arch Intern Med 2009 Oct 12; 169:1684
BRCA Testing of Women with Ovarian Cancer: Which Strategy Is Best?
Women's Health
Summary and Comment
Testing women of Ashkenazi Jewish ancestry or with family histories of breast or ovarian cancer was projected to be cost-effective for lowering subsequent cancer rates among first-degree relatives.
For Detecting CIN, Cytology Method Might Not Matter
Women's Health
Summary and Comment
Liquid-based cytology was as sensitive and specific as conventional Pap tests.
By Wendy S. Biggs, MD
November 19, 2009
Covering:
Siebers AG et al., JAMA 2009 Oct 28; 302:1757
Schiffman M and Solomon D., JAMA 2009 Oct 28; 302:1809
Contraception for Women Who Receive Anticoagulant Therapy for Venous Thrombosis
Women's Health
Practice Watch
The levonorgestrel IUD and injectable contraception are safe and effective options with noncontraceptive benefits.
When Biology Meets Personal Choices
Women's Health
Summary and Comment
Risks for ischemic stroke and myocardial infarction were substantially higher in women with lupus anticoagulant who smoked or used oral contraceptives.
By Anna Wald, MD, MPH
November 12, 2009
Covering:
Urbanus RT et al., Lancet Neurol 2009 Nov; 8:998
Vaginal Danazol for Abnormal Uterine Bleeding
Women's Health
Summary and Comment
Danazol shortened duration and diminished severity of menstrual bleeding with minimal side effects.
By Robert W. Rebar, MD
November 12, 2009
Covering:
Luisi S et al., Fertil Steril 2009 Oct; 92:1351
Can HPV Vaccination Combat Genital Warts?
Women's Health
Summary and Comment
Yes — and the benefit extends beyond vaccinated women to their male sexual partners.
By Anna Wald, MD, MPH
November 5, 2009
Covering:
Fairley CK et al., Sex Transm Infect 2009 Oct 16
Therapeutic HPV Vaccination for Preventing Progression of Vulvar Intraepithelial Neoplasia
Women's Health
Summary and Comment
Free
Clinical responses were achieved in women with grade 3 VIN who were vaccinated against HPV-16 viral oncoproteins.
By Anna Wald, MD, MPH
November 4, 2009
Covering:
Kenter GG et al., N Engl J Med 2009 Nov 5; 361:1838
Finn OJ and Edwards RP., N Engl J Med 2009 Nov 5; 361:1899
Oral Contraceptive Failure Rates
Women's Health
Summary and Comment
The OC failure rate in a large European cohort was 0.75% in the first year of use.
Estrogen-Progestin Therapy and Lung Cancer in Menopausal Women
Women's Health
Summary and Comment
Trying to make sense of a puzzle
By Andrew M. Kaunitz, MD
October 15, 2009
Covering:
Chlebowski RT et al., Lancet 2009 Oct 10; 374:1243
Ganti AK., Lancet 2009 Oct 10; 374:1217
Ethnicity Affects Attitudes About HPV Vaccination
Women's Health
Summary and Comment
Ethnic minority women in the U.K. were less likely than white women to know about HPV and to view vaccination as acceptable.
STI and HIV Services Fall Short for Sexually Active Young Women
General Medicine
Summary and Comment
More than one third of young women who receive contraceptive services are not concurrently offered STI or HIV services.
By Robert W. Rebar, MD
October 13, 2009
Covering:
Farr SL et al., Am J Obstet Gynecol 2009 Aug; 201:142.e1
Management of Chronic Pain
Comprehensive treatment for chronic pain must address both physical and psychological aspects.
By Lynn Rader, MD
October 8, 2009
Newly Approved Use for the LNG-IUS
Women's Health
News in Context
FDA approves the LNG-IUS for treating patients with menorrhagia.
New Options for HPV Vaccine
An FDA panel recommends approval of a new indication for the quadrivalent HPV vaccine and approval of a new HPV vaccine.
How Does Efficacy of the Contraceptive Patch Compare with That of OCs?
Women's Health
Summary and Comment
Rates of unintended pregnancy were <1% for both methods.
Is Laparoscopic Uterosacral Nerve Ablation Effective for Chronic Pelvic Pain?
Women's Health
Summary and Comment
British randomized trial results indicate the answer is no.
"Timing Hypothesis" for Hormone Therapy: Still Viable, or Time to Let Go?
In a new analysis, researchers examine outcomes associated with HT use in the early postmenopausal period.