Intraperitoneal Chemotherapy for Ovarian Cancer
Women's Health Summary and Comment
Median overall survival was 15.9 months longer among women who received intraperitoneal therapy than among those who received only standard IV therapy.
By Andrew M. Kaunitz, MD
February 21, 2006
Covering:
Armstrong DK et al., N Engl J Med 2006 Jan 5; 354:34-43
Cannistra SA., N Engl J Med 2006 Jan 5; 354:77-9
Lynch Syndrome: Reducing Gynecologic Cancer Risk
Women's Health Summary and Comment
More evidence that prophylactic surgery prevents cancers in women whose genetic makeup places them at high risk
By Andrew M. Kaunitz, MD
February 21, 2006
Covering:
Schmeler KM et al., N Engl J Med 2006 Jan 19; 354:261-9
Prophylactic Surgery Prevents Gynecologic Cancers in Women with Lynch Syndrome
Gastroenterology Summary and Comment
Prophylactic surgery is an option for women who are documented HNPCC carriers.
By Douglas K. Rex, MD
February 14, 2006
Covering:
Schmeler KM et al., N Engl J Med 2006 Jan 19; 354:261-9
Liquid-Based Cytology: No More Accurate Than Conventional Pap?
General Medicine Summary and Comment
Findings from a large meta-analysis suggest that liquid-based cytology is not more accurate, but evidence is insufficient to settle this question.
By Bruce Soloway, MD
February 7, 2006
Covering:
Davey E et al., Lancet 2006 Jan 14; 367:122-32
Obwegeser J and Schneider V., Lancet 2006 Jan 14; 367:88-9
High-Grade CIN: Risk Factors Above and Beyond HPV?
Women's Health Summary and Comment
Associations between infection with oncogenic strains of human papillomavirus (HPV) and high-grade cervical intraepithelial neoplasia (CIN) are well documented. Less clear, however, are the roles . . .
By Andrew M. Kaunitz, MD
February 7, 2006
Covering:
Castle PE et al., Int J Cancer 2005 Dec 20; 117:1007-12
Aggressive Surgical "Debulking" Improves Survival in Ovarian Cancer Patients
General Medicine Summary and Comment
Optimal cytoreduction, even if it involved radical surgery, improved 5-year survival rates.
By Robert W. Rebar, MD
February 3, 2006
Covering:
Aletti GD et al., Obstet Gynecol 2006 Jan; 107:77-85
Intraperitoneal Chemotherapy for Ovarian Cancer Prolongs Survival
General Medicine Summary and Comment
Free
The survival benefit seen in this study is one of the largest ever observed for a new therapy in gynecologic oncology.
By Robert W. Rebar, MD
January 13, 2006
Covering:
Armstrong DK et al., N Engl J Med 2006 Jan 5; 354:34-43
Cannistra SA., N Engl J Med 2006 Jan 5; 354:77-9
Levonorgestrel IUD Does Not Interfere with Breast-Feeding
Women's Health Summary and Comment
Postpartum progestin-only contraceptives generally do not alter the quality or quantity of breast milk, or the growth or development of the infant. To determine whether . . .
By Diane E. Judge, APN/CNP
January 10, 2006
Covering:
Shaamash AH et al., Contraception 2005 Nov; 72:346-51
Copper IUD: Permanent, Reversible Contraception?
Women's Health Summary and Comment
In 1984, the U.S. FDA approved the copper intrauterine device (IUD; ParaGard) as being safe and effective for 4 years, and eventually extended that period . . .
By Diane E. Judge, APN/CNP
January 10, 2006
Covering:
Bahamondes L et al., Contraception 2005 Nov; 72:337-41
Alternative Strategies for Preventing Cervical Cancer
Women's Health Summary and Comment
Current programs to prevent cervical cancer rely on regular cytologic evaluation of the cervix, with follow-up of abnormal Pap smear results. This sequence requires several . . .
By Anna Wald, MD, MPH
January 10, 2006
Covering:
Brewster WR et al., JAMA 2005 Nov 2; 294:2182-7
Denny L et al., JAMA 2005 Nov 2; 294:2173-81
Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) — in its purest form, characterized by unexplained hyperandrogenic chronic anovulation — affects approximately 7% of U.S. women.1
By Richard S. Legro, MD
January 10, 2006
Polycystic Ovary Syndrome: Not Just About Cysts
Women's Health Patient Information
About 7 of every 100 U.S. women have a condition called polycystic ovary syndrome (PCOS). In fact, PCOS is the most common hormonal problem in . . .
By Diane E. Judge, APN/CNP
January 10, 2006
Average Age at Menarche Continues to Decline
General Medicine Summary and Comment
The extent of decline varies substantially with race and ethnicity.
By Robert A. Dershewitz, MD, MSc
January 6, 2006
Covering:
Anderson SE and Must A., J Pediatr 2005 Dec; 147:753-60
Biro FM., J Pediatr 2005 Dec; 147:725-6
