Endoscopy Findings in Patients with Dyspepsia
General Medicine Summary and Comment
Self-reported dyspepsia didn't portend abnormal endoscopy findings.
By Allan S. Brett, MD
March 25, 2010
Covering:
Zagari RM et al., Am J Gastroenterol 2010 Mar; 105:565
Triple or Quadruple Therapy for Helicobacter pylori Infection?
Gastroenterology Summary and Comment
Eradication rates were similar but suboptimal.
Is It Eosinophilic Esophagitis or Reflux Disease?
Gastroenterology Summary and Comment
A predictive model reliably distinguished EoE from GERD.
By David A. Johnson, MD
March 5, 2010
Covering:
Dellon ES et al., Clin Gastroenterol Hepatol 2009 Dec; 7:1305
Preventing Recurrence of Aspirin-Related Peptic Ulcers
Gastroenterology Summary and Comment
Famotidine, a histamine-2–receptor antagonist, was less effective than pantoprazole, a proton-pump inhibitor.
Risk Factors for Peptic Ulcer Disease
Gastroenterology Summary and Comment
Several medical, behavioral, and demographic factors were independently associated with risk for PUD.
New Guidelines for Nonvariceal Upper Gastrointestinal Bleeding
Gastroenterology Clinical Practice Guideline Watch
Free
An update to the 2003 consensus recommendations
Stool Tests for Helicobacter pylori Infection
Infectious Diseases Summary and Comment
Free
Three stool assays using monoclonal antibodies to detect <$EMPH_O>Helicobacter pylori<$EMPH_C> antigens had sensitivities of 69%–92% and specificities of 76%–90% compared with gold standard.
By Neil M. Ampel, MD
February 17, 2010
Covering:
Calvet X et al., Clin Infect Dis 2010 Feb 1; 50:323
Barrett Esophagus and Colorectal Cancer
Gastroenterology Summary and Comment
Risk for developing CRC was higher in BE patients than in the general population.
By Douglas K. Rex, MD
February 12, 2010
Covering:
de Jonge PJF et al., Am J Gastroenterol 2010 Jan; 105:77
Mortality in Patients with Bleeding Peptic Ulcers
Gastroenterology Summary and Comment
Most deaths were attributed to causes unrelated to bleeding.
Bleeding Peptic Ulcers and End-Stage Renal Disease
Gastroenterology Summary and Comment
Among patients with bleeding ulcers, those with ESRD had higher risk for rebleeding than did those with chronic kidney disease or normal renal function.
Which Treatment Is Better for GERD?
Gastroenterology Summary and Comment
Free
Compared with medical therapy, surgery was associated with higher rates of continuous remission, but the results are questionable.
By David A. Johnson, MD
January 29, 2010
Covering:
Lundell L et al., Clin Gastroenterol Hepatol 2009 Dec; 7:1292
Barrett Esophagus and Neoplasia
Gastroenterology Summary and Comment
Use of proton-pump inhibitors was associated with diminished risk for high-grade dysplasia or esophageal adenocarcinoma.
By David A. Johnson, MD
January 29, 2010
Covering:
Nguyen DM et al., Clin Gastroenterol Hepatol 2009 Dec; 7:1299
Low-Dose Aspirin Therapy After Peptic Ulcer Bleeding
Gastroenterology Summary and Comment
Mortality risk was diminished in patients receiving low-dose aspirin for vascular disease.
A New Rapid Urease Test for H. pylori
Gastroenterology Summary and Comment
Test sensitivity at 5 minutes was 94.5%.
Proton-Pump Inhibitors and Fundic Gland Polyps
Gastroenterology Summary and Comment
Use of PPIs for >48 months was an independent predictor of FGPs.
SSRIs and Upper Gastrointestinal Bleeding
Gastroenterology Summary and Comment
A new case-control study confirms that use of selective serotonin reuptake inhibitors increases risk for bleeding, but questions remain.
Do Proton-Pump Inhibitors Decrease Bone-Mineral Density?
Gastroenterology Summary and Comment
PPI use was not associated with osteoporosis or accelerated bone-mineral density loss.
Is It Okay for Patients with Peptic Ulcer Bleeding to Continue Low-Dose Aspirin?
Cardiology Summary and Comment
For patients at cardiovascular risk, the short-term survival advantage of continuing aspirin therapy outweighed the bleeding risk.
By Joel M. Gore, MD
December 23, 2009
Covering:
Sung JJY et al., Ann Intern Med 2009 Dec 1
Reflux Esophagitis: A Novel Theory
Gastroenterology Summary and Comment
Gastric refluxate might not damage the esophagus directly but rather stimulate secretion of cytokines that mediate esophageal injury.
By David A. Johnson, MD
December 18, 2009
Covering:
Souza RF et al., Gastroenterology 2009 Nov; 137:1776
Eastern vs. Western Therapy for Upper Gastrointestinal Bleeding
Gastroenterology Summary and Comment
Endoscopic hemostasis methods differ, but the reasons why remain unclear.
Endoscopic Visualization of Bleeding Ulcers
Gastroenterology Summary and Comment
Hydrogen peroxide improved visualization of ulcer bases obscured by adherent clots.
Early vs. Late H. pylori Eradication
Gastroenterology Summary and Comment
Delaying treatment might increase risk for gastric cancer.
No Relation Between Asthma Control and Asymptomatic Acid Reflux
General Medicine Summary and Comment
Patients do not benefit from searching for silent reflux.
By Allan S. Brett, MD
December 1, 2009
Covering:
DiMango E et al., Am J Respir Crit Care Med 2009 Nov 1; 180:809
Trends in Uncomplicated Peptic Ulcer Disease
Gastroenterology Summary and Comment
Incidence in the U.K. declined by 50% during the last decade.
H. pylori and Gastric Cancer
Gastroenterology Summary and Comment
Eradication of <$EMPH_O>H. pylori<$EMPH_C> infection did not significantly reduce the incidence of gastric cancer.
