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GERD / Peptic Ulcers: Archives

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Trends in Uncomplicated Peptic Ulcer Disease

Incidence in the U.K. declined by 50% during the last decade.

H. pylori and Gastric Cancer

Eradication of <$EMPH_O>H. pylori<$EMPH_C> infection did not significantly reduce the incidence of gastric cancer.

PPIs and Clopidogrel: Data Trumps Fear

Antiplatelet function was diminished in PPI users, but cardiovascular outcomes were similar in PPI users and nonusers.

Does Coagulation Status Predict Band-Ulcer Bleeding After Band Ligation?

Neither standard nor expanded coagulation indices were predictive.

Early Endoscopy for Older Patients with Bleeding Peptic Ulcers

Compared with delayed endoscopies, early procedures were associated with shorter hospital stays and lower rates of surgery.

Endoscopy for Evaluation of Dyspepsia

Endoscopy detected few malignant lesions but still might merit the cost in patients aged 50 or older.

Trends in Upper Gastrointestinal Bleeding

During a 25-year period at an Italian hospital, the incidence of upper GI bleeding declined, as did associated mortality.

Peptic-Ulcer Bleeding: Trends in Sweden

Incidence of duodenal and gastric ulcers has declined.

Barrett Esophagus in Patients with Erosive Esophagitis

Approximately 9% of patients with EE had BE diagnosed during subsequent upper endoscopy.

Is Standard Ulcer Therapy Effective in Patients with Uremia?

A small study did not show benefit beyond 7 days.

Acid Symptoms After Proton-Pump–Inhibitor Discontinuation

Healthy volunteers developed acid-related symptoms after discontinuing a PPI that they had taken for 8 weeks.

Incidence of Gastrointestinal Bleeding and Perforation

The gap between upper and lower GI complications is narrowing.

Chronic Laryngeal Symptoms in Patients with GERD

Acid exposure to the larynx does not appear to be an important cause.

Proton-Pump Inhibitor Therapy After Endoscopic Submucosal Dissection

Degree of healing of endoscopic submucosal dissection–induced ulcers was dependent on initial ulcer size.

Famotidine Prevents GI Damage in Patients Who Take Low-Dose Aspirin

Gastric ulcers, duodenal ulcers, and erosive esophagitis were less common with famotidine use.

Prevention of Aspirin-Associated Gastroduodenal Ulcers

Patients who received famotidine, a histamine-2–receptor antagonist, had lower risk for ulcers or erosive esophagitis than those who received placebo.

Rebound Symptoms After Stopping PPIs

The findings are pertinent for patients who take PPIs unnecessarily.

Blood Type and Nonvariceal Upper GI Bleeding

An association between blood type O and nonvariceal upper gastrointestinal bleeding is not sufficient to imply causation.

Safety of PPIs in Pregnancy

PPI use was not associated with congenital malformations.

Arterial Embolization for Bleeding Peptic Ulcers

Coagulopathy and the use of coils alone for embolization are independently associated with rebleeding.

PPIs and Pneumonia, Revisited

Among non–critically ill inpatients, PPI therapy was associated with a 30% increase in risk for hospital-acquired pneumonia.

Higher Mortality for Weekend AUGIB Admissions

Patients admitted on weekends with peptic ulcer–related and nonvariceal acute upper gastrointestinal bleeding also had longer hospital stays and higher medical costs.

Predicting Mortality in Patients with Bleeding Ulcers

Investigators developed a prediction model for ulcer-related mortality after endoscopic therapy.

PPI Lowers Rate of Recurrent Peptic Ulcer Bleeding

The incidence of clinically significant recurrent bleeding was lower with esomeprazole than with placebo.

PPI Treatment for Acute GI Bleeding from Peptic Ulcer

Three days of IV PPI therapy reduced rebleeding for up to 30 days but did not affect mortality.

Items 1-25 of 170 are shown

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