GERD: Archives

Stress and GERD

• Gastroenterology
• Summary and Comment
• Subscription required

In patients with GERD, auditory stress increased perceptual response to intraesophageal acid exposure.

• By David A. Johnson, MD
• April 25, 2008
• Covering:
  • Fass R et al., Gastroenterology 2008 Mar; 134:696

FDA Approves Nexium for Young Children

• Pediatrics and Adolescent Medicine
• Drug Watch
• Free

Children older than 1 year with documented GERD or esophagitis now have another PPI choice.

• By Cornelius W. Van Niel, MD
• April 23, 2008

Test-and-Treat for H. pylori vs. Acid Suppression for Dyspepsia

• General Medicine
• Summary and Comment
• Subscription required

At 1 year, the two strategies for initial treatment were equally effective — or ineffective, depending on your perspective.

• By Paul S. Mueller, MD, MPH, FACP
• March 25, 2008
• Covering:
  • Delaney BC et al., BMJ 2008 Mar 22; 336:651
  • Chiba N., BMJ 2008 Mar 22; 336:623

Treating Reflux in Children

• General Medicine
• Summary and Comment
• Subscription required

Conservative nonpharmacologic therapy is a good initial approach for infants with symptoms that suggest GERD.

• By Howard Bauchner, MD
• March 18, 2008
• Covering:
  • Orenstein SR and McGowan JD., J Pediatr 2008 Mar; 152:310
  • Hassall E., J Pediatr 2008 Mar; 152:301

A Link Between BMI and GERD?

• Gastroenterology
• Summary and Comment
• Subscription required

Does obesity increase the risk for BE beyond its role in increasing the risk for GERD alone?

• CME

• By David A. Johnson, MD
• March 14, 2008
• Covering:
  • Cook MB et al., Am J Gastroenterol 2008 Feb; 103:292

Does Omeprazole Affect Antiplatelet Therapy?

• General Medicine
• Summary and Comment
• Subscription required

Circumstantial evidence shows that coadministration of clopidogrel and PPIs can affect platelet reactivity.

• By Kirsten E. Fleischmann, MD, MPH
• March 13, 2008
• Covering:
  • Gilard M et al., J Am Coll Cardiol 2008 Jan 22; 51:256
  • Gurbel PA et al., J Am Coll Cardiol 2008 Jan 22; 51:261

Treat Babies with Reflux Conservatively

• Pediatrics and Adolescent Medicine
• Summary and Comment
• Free

Conservative therapies are associated with improvement in infants with symptoms that suggest gastroesophageal reflux.

• CME

• By Cornelius W. Van Niel, MD
• March 12, 2008
• Covering:
  • Orenstein SR and McGowan JD., J Pediatr 2008 Mar; 152:310
  • Hassall E., J Pediatr 2008 Mar; 152:301

Empirical Esomeprazole vs. Endoscopy-Guided Treatment for GERD

• General Medicine
• Summary and Comment
• Subscription required

Empirical treatment of GERD without alarm symptoms was as effective as and less expensive than endoscopy-guided treatment.

• By Paul S. Mueller, MD, MPH, FACP
• March 11, 2008
• Covering:
  • Giannini EG et al., Am J Gastroenterol 2008 Feb; 103:267

Acid Pockets Might Contribute to GERD

• Gastroenterology
• Summary and Comment
• Subscription required

Postprandial gastroesophageal reflux might be exacerbated by acid pockets — small areas of unbuffered acid in the gastric cardia.

• CME

• By David A. Johnson, MD
• March 7, 2008
• Covering:
  • Clarke AT et al., Gut 2008 Mar; 57:292

Does Sleep Deprivation Worsen GERD Symptoms?

• Gastroenterology
• Summary and Comment
• Subscription required

Sleep deprivation might cause hyperalgesia in patients with GERD via enhanced perception of intraesophageal acid.

• By David A. Johnson, MD
• February 8, 2008
• Covering:
  • Schey R et al., Gastroenterology 2007 Dec; 133:1787