No Known Strategies Prevent Vertical HCV Transmission
Gastroenterology Summary and Comment
A systematic review of perinatal management strategies came up empty.
By Atif Zaman, MD, MPH
February 8, 2013
Covering:
Cottrell EB et al., Ann Intern Med 2013 Jan 15; 158:109
Recommended Adult Immunization Schedule for 2013
General Medicine Clinical Practice Guideline Watch
Free
Highlights of the updated recommendations and a link to the CDC's vaccine resources
By Jamaluddin Moloo, MD, MPH
February 14, 2013
Covering:
Advisory Committee on Immunization Practices., Ann Intern Med 2013 Feb 5; 158:191
Why Do Adults in the U.S. Use Dietary Supplements?
General Medicine Summary and Comment
A survey says mostly to improve or maintain overall health.
Mediterranean Diet Lowers Rates of Adverse Cardiovascular Events
General Medicine Summary and Comment
In a primary prevention trial, this diet modestly outperformed a low-fat diet.
Heart Failure with Breast Cancer Chemotherapy: A Risk Worth Taking Seriously
Cardiology Summary and Comment
Findings from a large database suggest that trastuzumab is associated with higher rates of HF or cardiomyopathy in clinical practice than it was in clinical trials.
Grappling with Racial Disparities in Breast Cancer
For multiple reasons, black women in the U.S. have lower incidence but substantially higher breast cancer mortality than white women.
By William J. Gradishar, MD
January 8, 2013
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2012 Nov 16; 61:922
Gonococcal Treatment Failure Due to Cephalosporin Resistance Now in North America
Infectious Diseases Summary and Comment
Cefixime- resistant strains in Toronto were highly related to those isolated in Europe.
By Richard T. Ellison III, MD
January 9, 2013
Covering:
Allen VG et al., JAMA 2013 Jan 9; 309:163
Kirkcaldy RD et al., JAMA 2013 Jan 9; 309:185
Cognitive-Behavioral Therapy for Patients with Treatment-Resistant Depression
General Medicine Summary and Comment
CBT added to antidepressant drugs was beneficial in primary care practices.
Low-Dose Aspirin and Dementia in Older Women
Neurology Summary and Comment
Does low-dose acetylsalicylic acid prevent cognitive decline in women with high cardiovascular risk?
By Jon Brillman, MD, FRCPI
December 11, 2012
Covering:
Kern S et al., BMJ Open 2012 Oct 3; 2:e001288
When to Introduce Complementary Foods in Breast-Fed Infants
Breast-fed infants who were given complementary foods at age 4 months had similar growth rates and better iron status at age 6 months than exclusively breast-fed infants.
By Louis M. Bell, MD
January 9, 2013
Covering:
Jonsdottir OH et al., Pediatrics 2012 Dec; 130:1038
Does Lack of Sunlight in Pregnancy Increase the Risk for Multiple Sclerosis?
Neurology Summary and Comment
Two recent studies come to divergent conclusions on maternal vitamin D in pregnancy and MS in offspring.
By Robert T. Naismith, MD
November 27, 2012
Covering:
Dobson R et al., J Neurol Neurosurg Psychiatry 2012 Nov 14
Salzer J et al., Neurology 2012 Nov 20; 79:2140
Use Ursodeoxycholic Acid First for Intrahepatic Cholestasis of Pregnancy
Gastroenterology Summary and Comment
Free
This therapy safely improved both maternal and fetal outcomes.
Tanning Increases BCC in Young Adults — More Evidence
Dermatology Summary and Comment
Indoor tanners are much more likely than others to develop basal cell carcinoma before age 40; the risk is pronounced in young women.
By Murad Alam, MD, MSCI
November 16, 2012
Covering:
Ferrucci LM et al., J Am Acad Dermatol 2012 Oct; 67:552
Risky Sexual Behavior Is Common Among Teens with Perinatally Acquired HIV Infection
Equally worrisome: Nonadherence to antiretroviral therapy often accompanies sexual activity.
By Abigail Zuger, MD
November 26, 2012
Covering:
Tassiopoulous K et al., Clin Infect Dis 2012 Nov 7
HPV Vaccination Does Not Change Sexual Behaviors in Teens
Girls aged 11 to 12 years who received the human papillomavirus vaccine did not subsequently have higher rates of sexually transmitted disease diagnoses or pregnancy than girls who did not receive the HPV vaccine.
Long-Term PPI Use Does Not Accelerate Loss of Bone Mineral Density
Gastroenterology Summary and Comment
Proton-pump inhibitor users had lower bone mineral density values than nonusers at study entry, but there was no difference in bone mineral density changes during the next 10 years.
Endometriosis Associated with Inflammatory Bowel Disease
Gastroenterology Summary and Comment
Free
Women with endometriosis had elevated risk for ulcerative colitis and Crohn disease, even more than 20 years after their diagnoses.
Both HIV Infection and ART Use Associated with Increased Risk for Adverse Birth Outcomes
Use of ART during pregnancy was associated with increased risk for preterm delivery, small size for gestational age, and stillbirth.
By Keith Henry, MD
October 29, 2012
Covering:
Chen JY et al., J Infect Dis 2012 Oct 12
How Well Do Pregnant Women Adhere to ART?
HIV/AIDS Clinical Care Summary and Comment
Free
Not well enough: Suboptimal adherence rates may compromise the global elimination of mother-to-child HIV transmission.
By Abigail Zuger, MD
October 29, 2012
Covering:
Nachega JB et al., AIDS 2012 Oct 23; 26:2039
Carotid Intima–Media Thickness for Cardiovascular Risk Assessment
Cardiology Summary and Comment
In a large meta-analysis, addition of the test did not substantially improve Framingham risk classification.
Long-Term Health Benefits of Gastric Bypass Surgery
General Medicine Summary and Comment
Diabetes remission rate was 62% at 6 years, almost 10-fold higher than in severely obese patients who did not have bariatric surgery.
MRI Abnormalities Are Found in Most Older Adults' Knees
General Medicine Summary and Comment
Magnetic resonance imaging detected features of osteoarthritis in 90% of people without knee pain or radiographic evidence of OA.
The Key to Longevity After Age 75?
General Medicine Summary and Comment
Don't smoke, have rich social interactions, and engage in leisure activities.
Trends in HIV Risk Behaviors in Teens from 1991 to 2011
Improvements in the first decade are now dangerously stalled.
By Peggy Sue Weintrub, MD
August 15, 2012
Covering:
Centers for Disease Control and Prevention (CDC)., MMWR Morb Mortal Wkly Rep 2012 Jul 27; 61:556
Revised DHHS Guidelines for Perinatal Antiretroviral Use
HIV/AIDS Clinical Care Clinical Practice Guideline Watch
Free
The new guidelines offer more treatment options for pregnant HIV-infected women and explore the range of options available for safe conception in HIV-serodiscordant couples.
By Sally Hodder, MD
August 30, 2012
Covering:
Panel on Treatment of HIV-Infected Pregnant Women and Prevention of Perinatal Transmission.,
