Guanfacine and Clonidine: What Are Their Roles in ADHD Treatment in Children?
Guanfacine was associated with significant improvements in hyperactivity and impulsivity, and parents, but not teachers, reported improvements with clonidine.
By Martin T. Stein, MD
March 26, 2008
Covering:
Biederman J et al., Pediatrics 2008 Jan; 121:e73
Palumbo DR et al., J Am Acad Child Adolesc Psychiatry 2008 Feb; 47:180
When Are Temper Tantrums in Preschool Children Cause for Concern?
Pediatrics and Adolescent Medicine
Summary and Comment
Subscription required
Typical tantrum characteristics in healthy preschoolers differ from those of preschoolers with depression or disruptive disorders.
Brain Activity and Belief
General Medicine
Summary and Comment
Subscription required
Functional MRI shows that we use different brain regions to judge whether statements are true, false, or open to doubt.
Education Level Affects Dementia Diagnosis
Neurology
Summary and Comment
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Educational achievement is associated with both delay in dementia diagnosis and accelerated memory decline after diagnosis.
By Dorene M. Rentz, PsyD
February 19, 2008
Covering:
Hall CB et al., Neurology 2007 Oct 23; 69:1657
Antidepressant Choice and Psychotherapy in Treatment-Resistant Adolescents
General Medicine
Summary and Comment
Free
Cognitive behavioral therapy adds incremental benefit to any antidepressant therapy.
Counteracting Antipsychotic-Induced Weight Gain
General Medicine
Summary and Comment
Subscription required
Structured lifestyle modification and metformin together were most effective.
More on Genes That Cause Autism
Pediatrics and Adolescent Medicine
Summary and Comment
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The list of syndromes, chromosomal abnormalities, and specific genes associated with ASD is growing.
By Judith G. Hall, OC, MD
January 23, 2008
Covering:
Alarcón M et al., Am J Hum Genet 2008 Jan; 82:150
Arking DE et al., Am J Hum Genet 2008 Jan; 82:160
Bakkaloglu B et al., Am J Hum Genet 2008 Jan; 82:165
Kim H-G et al., Am J Hum Genet 2008 Jan; 82:199
Stephan DA., Am J Hum Genet 2008 Jan; 82:7
Idiopathic Hypersomnia: Still Idiopathic
Neurology
Summary and Comment
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This descriptive article of clinical characteristics is marred by use of a nonstandard definition.
By Brian J. Murray MD, FRCP(C), D, ABSM
January 22, 2008
Covering:
Anderson KN et al., Sleep 2007 Oct 1; 30:1274
Alcohol Screening and Brief Counseling Are Cost-Saving
General Medicine
Summary and Comment
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But its hardly ever done in primary care.
The Safety of Stimulants in Children
Pediatrics and Adolescent Medicine
Summary and Comment
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Death and hospitalization rates from cardiac causes are similar among current, former, and nonusers of stimulants.
By Howard Bauchner, MD
January 2, 2008
Covering:
Winterstein AG et al., Pediatrics 2007 Dec; 120:e1494