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HIV/AIDS Editor's Picks: Archives

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Items 1-25 of 396 are shown

Neurologic Effects of Early HIV Infection

Significant structural brain changes are found within the first 6 months of HIV infection.

Sexually Transmitted Infections Acquired During Travel

A GeoSentinel analysis identified several risk factors for travel-associated STIs, including male sex and lack of a pretravel health consultation.

Renal Safety of Treatment for Chronic HBV Infection

Nephrotoxicity was similar with tenofovir or entecavir.

High and Varied Levels of Multidrug-Resistant Tuberculosis

Among isolates from patients with MDR-TB, 44% showed resistance to at least one second-line drug, and 7% were extensively resistant.

Reducing the Rate of Active TB by Targeted Testing and Treatment

Such a program, initiated by the Tennessee Department of Health, prevented an estimated 184 cases of active tuberculosis during its first 5 years.

HBV or HCV Infection: Which Is Worse?

In a cohort of men who have sex with men, hepatitis B virus infection conferred a higher risk for liver-related mortality than did hepatitis C virus infection.

Trends in HIV Risk Behaviors in Teens from 1991 to 2011

Improvements in the first decade are now dangerously stalled.

Antiviral Therapy Safely Stopped in HBeAg-Negative Patients with Hepatitis B Infection

Discontinuing adefovir did not lead to any adverse events during 5.5 years of follow-up.

False-Positive Interferon Assays for Latent Tuberculosis

One hospital's experience suggests routinely repeating tests in converters.

Metronidazole for TB?

A 2-month metronidazole regimen was as effective as a 6-month isoniazid regimen in a macaque model of latent TB.

Tuberculosis Is Seasonal in the U.S.

Analysis of 16 years of CDC data suggests a spring peak and a fall trough in cases resulting from recent infection.

Multidrug-Resistant Tuberculosis — Good News, Bad News

A phase II clinical trial of a novel agent offers hope, even as survey results from China prompt serious concern.

The Benefits of Contact Investigation for TB

Active TB was diagnosed in 1% of contacts within 4 years after exposure; chemoprophylaxis of those with latent infection significantly reduced the risk for active disease.

Time to Broaden HCV Testing?

Improvements in treatment are changing the calculus of screening the general population for hepatitis C virus infection.

New Tests Predict Clinical Outcomes in Chronic Hepatitis C Virus

A battery of quantitative liver-function tests might provide a noninvasive method of risk assessment.

A Review of Drug Interactions of Telaprevir and Boceprevir

A compendium of information on how these protease inhibitors interact with other drugs often needed by patients with HCV infection

A Recombinant Vaccine for Tuberculosis

In a phase IIa trial, vaccination with MVA85A was well tolerated and induced T-cell responses in individuals with HIV infection, Mtb infection, or both.

Exploring Immunity to Hepatitis C

Researchers have identified an anti–hepatitis C monoclonal antibody that is broadly cross-reactive and is protective in a mouse model.

HCV Genotype Might Affect Response in Interferon-Free Regimens

In a small exploratory analysis, patients with <$EMPH_O>IL28B<$EMPH_C> genotype CC trended towards greater reductions in viral load than those with genotypes TT or CT.

TMP-SMX–Associated Renal Toxicity

Acute kidney injury occurred in 11% of TMP-SMX recipients but nearly always resolved after drug discontinuation.

Do HIV-Positive Women with Prior Hysterectomies Require Pap Testing?

Although HIV-positive women frequently have abnormal Pap results, the absolute risk for vaginal dysplasia and malignancy is low.

Mortality Rate Now Higher for HCV Than HIV Infection in the U.S.

As many as 75% of people with HCV infection do not know that they are infected; a one-time screening holds promise for identifying and treating them.

Highly Azithromycin-Resistant Gonococcus Identified in the U.S.

This discovery bodes ill for treatment of gonorrhea.

Correlating Xpert MTB/RIF Results with Sputum Smear Status

In a study involving 130 patients with pulmonary tuberculosis, an Xpert MTB/RIF cycle time >31.8 indicated an 80% likelihood of smear negativity.

Testing Midstream Urine for Chlamydia trachomatis

Midstream samples might be adequate for evaluating both chlamydial and urinary tract infections, but study results were not definitive.

Items 1-25 of 396 are shown

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