Muscular Strength and Long-Term Mortality in Men
General Medicine Summary and Comment
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Muscular strength was associated inversely with death from all causes or from cancer.
Methotrexate plus Etanercept for Early, Moderate-to-Severe RA
General Medicine Summary and Comment
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Likelihood of remission and of radiographic nonprogression was greater with combination therapy than with methotrexate alone.
By Thomas L. Schwenk, MD
August 12, 2008
Covering:
Emery P et al., Lancet 2008 Aug 2; 372:375
Kremer JM., Lancet 2008 Aug 2; 372:347
Rhythm vs. Rate Control in Patients with Atrial Fibrillation and Heart Failure
General Medicine Summary and Comment
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The primary outcome of cardiovascular death did not significantly differ by treatment group.
By Kirsten E. Fleischmann, MD, MPH
June 26, 2008
Covering:
Roy D et al., N Engl J Med 2008 Jun 19; 358:2667
Cain ME and Curtis AB., N Engl J Med 2008 Jun 19; 358:2725
Hazards of Warfarin Plus Antiplatelet Therapy
General Medicine Summary and Comment
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In U.S. and European studies, treatment with warfarin plus antiplatelet agents was associated with serious bleeding episodes.
By Allan S. Brett, MD
June 26, 2008
Covering:
Rogacka R et al., J Am Coll Cardiol Intv 2008 Feb 1; 1:56
Johnson SG et al., Chest 2008 Apr; 133:948
Surgery vs. Nonoperative Treatment for Sciatica: Follow-Up After 2 Years
General Medicine Summary and Comment
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Short-term results were better with surgery, but outcomes were similar between groups at 1 year and 2 years.
Rapid Serious Adverse Events with Antipsychotics in Dementia
Psychiatry Summary and Comment
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Even short-term use of typical or atypical medications produces serious events.
By Peter Roy-Byrne, MD
June 23, 2008
Covering:
Rochon PA et al., Arch Intern Med 2008 May 26; 168:1090
Last Resort for Drug-Resistant Infections: Honey?
General Medicine Summary and Comment
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"Medical-grade" honey has attractive microbicidal properties.
By Abigail Zuger, MD
July 3, 2008
Covering:
Kwakman PHS et al., Clin Infect Dis 2008 Jun 1; 46:1677
Perioperative Antibiotic Prophylaxis Is a Risk Factor for C. difficile Infection
General Medicine Summary and Comment
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Even if patients receive no other antibiotics, they can develop colitis.
By Abigail Zuger, MD
July 3, 2008
Covering:
Carignan A et al., Clin Infect Dis 2008 Jun 15; 46:1838
Another Study of Medical Expulsive Therapy for Ureteral Stones
General Medicine Summary and Comment
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These findings strengthen the case for medical expulsive therapy in patients with small-to-moderate distal ureteral calculi.
Metronidazole vs. Vancomycin for CDAD
Infectious Diseases Summary and Comment
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After 5 days of therapy, resolution of diarrhea and suppression of <$EMPH_O>C. difficile<$EMPH_C> to undetectable levels were significantly more likely with vancomycin than with metronidazole.
By Neil M. Ampel, MD
June 25, 2008
Covering:
Al-Nassir WN et al., Clin Infect Dis 2008 Jul 1; 47:56
