Focused PSA Screening Strategy, Based on Empirical Data
General Medicine Summary and Comment
Three lifetime prostate-specific antigen tests (age: mid 40s, early 50s, and 60) are sufficient for at least half of men.
Uptake and Effectiveness of Zoster Vaccine in the General Population
Infectious Diseases Summary and Comment
Only 3.9% of the general U.S. population aged
By Thomas Glück, MD
May 1, 2013
Covering:
Langan SM et al., PLoS Med 2013 Apr 9; 10:e1001420
CPAP vs. Mandibular Advancement Device for Obstructive Sleep Apnea
General Medicine Summary and Comment
Adherence and some quality-of-life measures were better with the device than with continuous positive airway pressure.
By Allan S. Brett, MD
April 25, 2013
Covering:
Phillips CL et al., Am J Respir Crit Care Med 2013 Apr 15; 187:879
Prostate Cancer Screening: One More Take
General Medicine Clinical Practice Guideline Watch
The American College of Physicians has issued guidance for clinicians.
Vitamin D and Calcium: What Women Need at Midlife and After
Women's Health Patient Information
Both nutrients are important for bone health.
Midlife Cardiorespiratory Fitness Might Attenuate Later-Life Dementia
General Medicine Summary and Comment
Later dementia was less common among people who were more fit before age 65.
Intensive Life Support After Major Surgery: The Surgeon's Perspective
General Medicine Summary and Comment
Many surgeons believe that withdrawing life support during the first postoperative week is unacceptable.
By Patricia Kritek, MD
March 12, 2013
Covering:
Paul Olson TJ et al., JAMA Surg 2013 Jan; 148:29
Schwarze ML et al., Crit Care Med 2013 Jan; 41:1
Does Anti–Tumor Necrosis Factor Therapy Elevate Herpes Zoster Risk?
General Medicine Summary and Comment
For patients with rheumatoid arthritis, inflammatory bowel disease, and psoriasis, anti-TNF therapy poses no excess risk for HZ.
HSV-1 Infection More Common Than HSV-2 — and Now Often Genital
Infectious Diseases Summary and Comment
In a prospective study involving HSV-seronegative women, incidence of HSV-1 infection was more than double that of HSV-2 infection; most symptomatic HSV-1 infections were genital.
By Neil M. Ampel, MD
February 20, 2013
Covering:
Bernstein DI et al., Clin Infect Dis 2013 Feb 1; 56:344
Whitley RJ., Clin Infect Dis 2013 Feb 1; 56:352
Managing Venous Thromboembolism in Cancer Patients
Oncology and Hematology Clinical Practice Guideline Watch
A summary of new guidelines for prevention and treatment
By David Green, MD, PhD
February 5, 2013
Covering:
Farge D et al., J Thromb Haemost 2013 Jan; 11:56
Debourdeau P et al., J Thromb Haemost 2013 Jan; 11:71
Lifting the Taboo on Eggs
General Medicine Summary and Comment
Meta-analysis shows little association between egg consumption and coronary heart disease or stroke.
CPR: Compression-Only Wins the Long Race
Emergency Medicine Summary and Comment
Bystanders, forget about the breaths — pump that chest!
Increasing Doses of Citalopram, Escitalopram, and Amitriptyline are Associated with QT Interval Prolongation
General Medicine Summary and Comment
These observational results support the FDA's warning about cardiac changes.
Recommended Adult Immunization Schedule for 2013
General Medicine Clinical Practice Guideline Watch
Free
Highlights of the updated recommendations and a link to the CDC's vaccine resources
By Jamaluddin Moloo, MD, MPH
February 14, 2013
Covering:
Advisory Committee on Immunization Practices., Ann Intern Med 2013 Feb 5; 158:191
Time Lag to Survival Benefit After Colorectal and Breast Cancer Screening
General Medicine Summary and Comment
After about 10 years, 1 colorectal cancer–related and 1 breast cancer–related death were prevented per 1000 people screened.
Extended Treatment After Unprovoked Venous Thromboembolism
General Medicine Summary and Comment
Free
Apixaban, which is not yet FDA-approved for VTE, lowered recurrence by about 7 percentage points during 1 year.
Bisphosphonate-Associated Atypical Femur Fractures: A Case Series
General Medicine Summary and Comment
Index fractures occurred after a mean 9 years of bisphosphonate therapy.
By Allan S. Brett, MD
January 3, 2013
Covering:
Schneider JP et al., J Clin Endocrinol Metab 2012 Dec; 97:4324
Thrombosis Prophylaxis for Medical Inpatients: How Do We Weigh Risks and Benefits?
Risk factors for thrombosis and bleeding are well known, but no validated models exist to balance them for individual patients.
Risk and Adverse Effects of Energy Drink Consumption
General Medicine Summary and Comment
Risks are particularly elevated when heavily caffeinated drinks are mixed with alcohol.
By Thomas L. Schwenk, MD
January 3, 2013
Covering:
Sepkowitz KA., JAMA 2012 Dec 19
Howland J and Rohsenow DJ., JAMA 2012 Dec 19
Rotavirus Outbreaks in Retirement Communities
General Medicine Summary and Comment
Rotavirus probably is an underrecognized pathogen in older adults.
USPSTF Again Recommends Against Postmenopausal Hormone Therapy for Chronic Disease Prevention
General Medicine Clinical Practice Guideline Watch
The task force suggests no change from its 2005 recommendations.
By Allan S. Brett, MD
November 8, 2012
Covering:
Moyer VA et al., Ann Intern Med 2012 Oct 23
Statins as Anticancer Drugs?
General Medicine Summary and Comment
Free
In an observational study with limitations, statin use by cancer patients was associated with lower 3-year mortality.
By Allan S. Brett, MD
November 8, 2012
Covering:
Nielsen SF et al., N Engl J Med 2012 Nov 8; 367:1792
Caporaso NE., N Engl J Med 2012 Nov 8; 367:1848
Does Early Otitis Media Lead to IBD?
Another potential long-term consequence of indiscriminate antibiotic use
Understanding the Effect of Healthcare Workers' Hand Hygiene
Infectious Diseases Summary and Comment
Free
Using a novel method, investigators revealed marked heterogeneity in healthcare worker interactions and in the potential consequences of their hand hygiene.
Oral Corticosteroids Do Not Increase the Incidence of Nonmelanoma Skin Cancers
Dermatology Summary and Comment
Skin cancer is one of the few effects that physicians do not have to worry about in long-term systemic corticosteroid users.
By Craig A. Elmets, MD
October 12, 2012
Covering:
Baibergenova AT et al., J Eur Acad Dermatol Venereol 2012 Sep; 26:1109
