Patients with Diabetes Fare Worse After MI Than Those Without Diabetes
Cardiology Summary and Comment
Improvements in treatment have not narrowed the mortality gap between diabetic and nondiabetic ACS patients.
By JoAnne M. Foody, MD
August 22, 2007
Covering:
Donahoe SM et al., JAMA 2007 Aug 15; 298:765-75
Rosiglitazone Cardiovascular Effects Uncertain
General Medicine Summary and Comment
The safety of this diabetes drug remains open to question.
Are Nonfasting Better Than Fasting Triglyceride Levels at Predicting Cardiac Events?
Cardiology Summary and Comment
Free
In two large cohort studies, CVD risk correlated more strongly with nonfasting than with fasting levels, but the clinical significance of hypertriglyceridemia is still unclear.
By JoAnne M. Foody, MD
August 8, 2007
Covering:
Bansal S et al., JAMA 2007 Jul 18; 298:309-16
Nordestgaard BG et al., JAMA 2007 Jul 18; 298:299-308
McBride PE., JAMA 2007 Jul 18; 298:336-8
PCI vs. Fibrinolysis in Patients with ST-Elevation MI and Diabetes
Cardiology Summary and Comment
In a meta-analysis, the relative benefit of percutaneous coronary intervention in patients with diabetes was similar to that in patients without diabetes.
By Frederick A. Masoudi, MD MSPH
August 8, 2007
Covering:
Timmer JR et al., Arch Intern Med 2007 Jul 9; 167:1353-9
Diabetes and Death: The Great Equalizers Among Women and Men
Women's Health Summary and Comment
The mortality rate has decreased in diabetic men but increased in diabetic women, and the difference in mortality rates between diabetic and nondiabetic women has more than doubled.
By Wendy S. Biggs, MD
August 2, 2007
Covering:
Gregg EW et al., Ann Intern Med 2007 Aug 7; 147:1-8
Comparing Safety and Efficacy of Medications for Type 2 Diabetes
General Medicine Summary and Comment
Older (and therefore cheaper) drugs are as good as, or better than, newer ones.
By Richard Saitz, MD, MPH, FACP, FASAM
July 26, 2007
Covering:
Bolen S et al., Ann Intern Med 2007 Jul 16
Primary Aldosteronism Among Diabetic Patients with Resistant Hypertension
General Medicine Summary and Comment
Primary aldosteronism was confirmed in 14% of patients.
By Allan S. Brett, MD
July 26, 2007
Covering:
Umpierrez GE et al., Diabetes Care 2007 Jul; 30:1699-703
What’s the Best Treatment for Painful Diabetic Neuropathy?
General Medicine Summary and Comment
Tricyclic antidepressants and traditional anticonvulsants still appear to be the drugs of choice.
By Keith I. Marton, MD
July 26, 2007
Covering:
Wong M-C et al., BMJ 2007 Jul 14; 335:87
Galloping Acanthosis Nigricans with Insulin Resistance
Dermatology Summary and Comment
In a patient with anti-insulin-receptor-antibody–related insulin resistance, normalization of blood sugar improved the AN.
By Lowell A. Goldsmith, MD, MPH
July 20, 2007
Covering:
Fareau GG et al., Metabolism 2007 May; 56:670-5
Beyond Skin and Joints: Psoriasis and the Metabolic Syndrome
Dermatology Summary and Comment
Researchers identified the metabolic syndrome in 30% of psoriasis patients seen at tertiary skin centers.
By Jeffrey P. Callen, MD
July 13, 2007
Covering:
Gisondi P et al., Br J Dermatol 2007 Jul; 157:68-73
Initiating Insulin Therapy in Group Sessions
General Medicine Summary and Comment
It’s a cost-effective approach.
By Allan S. Brett, MD
July 10, 2007
Covering:
Yki-Järvinen H et al., Diabetes Care 2007 Jun; 30:1364-9
Simple Oral Treatment Greatly Reduces Both Atherosclerosis and Diabetes in Mice
General Medicine Summary and Comment
The discovery might lead to a new class of pharmaceuticals.
By Anthony L. Komaroff, MD
July 5, 2007
Covering:
Furuhashi M et al., Nature 2007 Jun 21; 447:959-65
Self-Monitoring of Glucose in Type 2 Diabetes
General Medicine Summary and Comment
Free
Monitoring had only a minimal effect on glucose control and other measures.
By Keith I. Marton, MD
July 3, 2007
Covering:
Farmer A et al., BMJ 2007 Jun 25
Abnormal Glucose Metabolism and Mortality
Cardiology Summary and Comment
Free
In a population-based, Australian study, even mild forms of hyperglycemia were associated with increased risk.
By Joel M. Gore, MD
June 27, 2007
Covering:
Barr ELM et al., Circulation 2007 Jun 18
Rosiglitazone: More Data, Continuing Concern
General Medicine Summary and Comment
An editorialist concludes that clinicians should no longer feel comfortable prescribing the diabetes drug.
By Allan S. Brett, MD
June 12, 2007
Covering:
Home PD et al., N Engl J Med 2007 Jun 5
Nathan DM., N Engl J Med 2007 Jun 5
Long-Term Cognitive Sequelae of Severe Hypoglycemia
Neurology Summary and Comment
Free
Tight glycemic control leads to frequent episodes of severe hypoglycemia but produces no measurable cognitive deficit even 18 years later.
By Daniel Press, MD
June 12, 2007
Covering:
Jacobson AM et al., N Engl J Med 2007 May 3; 356:1842-52
More Data on Rosiglitazone and Cardiovascular Risk
Cardiology Summary and Comment
Free
Interim results from RECORD fail to clarify safety issues.
By Harlan M. Krumholz, MD, SM
June 6, 2007
Covering:
Home PD et al. for the RECORD Study Group., N Engl J Med 2007 Jun 5
Does Initial Glucose Level Have Prognostic Value in Acute MI?
Emergency Medicine Summary and Comment
Free
Yes. It is an independent predictor of short-term and long-term adverse outcomes in patients with a first MI.
By Richard D. Zane, MD, FAAEM
June 1, 2007
Covering:
Hsu C-W et al., Ann Emerg Med 2007 May; 49:618-26
Rosiglitazone May Increase Risk for Myocardial Infarction
General Medicine Summary and Comment
Free
Despite methodologic limitations, this study alerts us to the possibility of serious adverse cardiovascular effects with this drug.
By Allan S. Brett, MD
May 24, 2007
Covering:
Nissen SE and Wolski K., N Engl J Med 2007 Jun 14
Psaty BM and Furberg CD., N Engl J Med 2007 Jun 14
Rosiglitazone Associated with Increased Risk for MI
Cardiology Summary and Comment
Free
A common treatment for type 2 diabetes may have serious adverse cardiovascular effects.
By Harlan M. Krumholz, MD, SM
May 21, 2007
Covering:
Nissen SE and Wolski K., N Engl J Med 2007 Jun 14
Psaty BM and Furberg CD., N Engl J Med 2007 Jun 14
Choosing to Avoid Diabetes
Women's Health Summary and Comment
Free
Adherence to 2005 dietary guidelines reduced insulin resistance in women.
By Diane E. Judge, APN/CNP
May 17, 2007
Covering:
Fogli-Cawley JJ et al., Diabetes Care 2007 Apr; 30:817-22
Glucose Regulation When Premature Infants Grow Up
Very low birth weight was associated with impaired glucose regulation in adulthood.
By Howard Bauchner, MD
May 16, 2007
Covering:
Hovi P et al., N Engl J Med 2007 May 17; 356:2053-63
Ingelfinger JR., N Engl J Med 2007 May 17; 356:2093-5
Insulin Glargine vs. Rosiglitazone: Quality-of-Life Outcomes
General Medicine Summary and Comment
Add-on therapy with insulin glargine appeared to have superior results, despite similar glycemic control.
By Allan S. Brett, MD
May 3, 2007
Covering:
Vinik AI and Zhang Q., Diabetes Care 2007 Apr; 30:795-800
Rosiglitazone May Reduce Bone Density
General Medicine Summary and Comment
Bone density at the hip decreased by 2% in postmenopausal women taking rosiglitazone.
By Allan S. Brett, MD
April 24, 2007
Covering:
Grey A et al., J Clin Endocrinol Metab 2007 Apr; 92:1305-10
The Highs and Lows of Exercise and Diabetes
Glucose needs increase not only during exercise but also 7 to 11 hours later.
By Alain Joffe, MD, MPH, FAAP
April 18, 2007
Covering:
McMahon SK et al., J Clin Endocrinol Metab 2007 Mar; 92:963-8
Tamborlane WV., J Clin Endocrinol Metab 2007 Mar; 92:815-6
