Group Visits for Diabetes Patients
General Medicine
Summary and Comment
Group visits led to better blood pressure control but not better glycemic control.
Differences in Glycosylated Hemoglobin — Independent of Glucose Levels — Between Blacks and Whites
General Medicine
Summary and Comment
Using a single HbA1c level as an indicator of diabetes might not be as straightforward as it seems.
By Jamaluddin Moloo, MD, MPH
June 24, 2010
Covering:
Ziemer DC et al., Ann Intern Med 2010 Jun 15; 152:770
Herman WH and Cohen RM., Ann Intern Med 2010 Jun 15; 152:815
Metabolic Syndrome and Risk for Myocardial Infarction
General Medicine
Summary and Comment
Risk conferred by metabolic syndrome was similar to that conferred by diabetes alone.
Long-Term Metformin Raises Risk for B12 Deficiency
General Medicine
Summary and Comment
Routine B12 monitoring is recommended.
Hamburgers, Hot Dogs, and Heart Health
Cardiology
Summary and Comment
In a meta-analysis of observational data, consumption of processed meat conferred higher risks for coronary heart disease and diabetes than consumption of unprocessed red meat.
Staying Ahead of the Curve
Cardiology
Summary and Comment
Researchers relate trends in cardiovascular prevention and treatment to recent improvements in mortality from coronary heart disease.
Glycemic Control and Mortality in Hemodialysis Patients
General Medicine
Summary and Comment
Management of dialysis patients should not be focused on tight glycemic control.
By Allan S. Brett, MD
May 27, 2010
Covering:
Shurraw S et al., Am J Kidney Dis 2010 May; 55:875
Depression Worsens Outcome in Chronic Kidney Disease
Psychiatry
Summary and Comment
Free
The association is broadened to predialysis patients.
Treatment-Induced Diabetic Neuropathy
General Medicine
Summary and Comment
Free
An unusual complication of rapid intensive glycemic control
By Allan S. Brett, MD
May 20, 2010
Covering:
Gibbons CH and Freeman R., Ann Neurol 2010 Apr; 67:534
Liraglutide vs. Sitagliptin for Type 2 Diabetes: Liraglutide Wins an Early Round
General Medicine
Summary and Comment
Mean decreases in glycosylated hemoglobin and fasting glucose levels were significantly greater with liraglutide.
By Bruce Soloway, MD
May 18, 2010
Covering:
Pratley RE et al., Lancet 2010 Apr 24; 375:1447
Addicted to Food
Psychiatry
Summary and Comment
A study in rats reveals dysfunction in the reward system with unlimited access to rich foods, similar to cocaine addictions.
By Steven Dubovsky, MD
May 17, 2010
Covering:
Johnson PM and Kenny PJ., Nat Neurosci 2010 May; 13:635
Diabetic Nephropathy Worsens with B-Vitamin Supplementation
General Medicine
Summary and Comment
Plasma homocysteine levels declined, but so did glomerular filtration rates.
General Medicine
Summary and Comment
In mice, in vivo depletion of β cells caused cells to become β cells.
A Mathematical Model Supports Age-Based Screening for Diabetes
General Medicine
Summary and Comment
A cost-effectiveness analysis supports starting screening between the ages of 30 and 45.
By Bruce Soloway, MD
April 27, 2010
Covering:
Kahn R et al., Lancet 2010 Apr 17; 375:1365
Industry Affiliation and Position on the Rosiglitazone Controversy
General Medicine
Summary and Comment
Authors with industry links were more likely to have positive views about rosiglitazone's risk profile.
Women from JUPITER . . .
Cardiology
Summary and Comment
. . . benefited from rosuvastatin as much as men did.
By JoAnne M. Foody, MD
April 14, 2010
Covering:
Mora S et al., Circulation 2010 Mar 9; 121:1069
Salsalate Treatment Lowers Glycosylated Hemoglobin Levels
General Medicine
Summary and Comment
Long-term safety data are needed before salsalate can be used routinely in patients with type 2 diabetes.
Frequency of Visits Before New Diagnosis of Diabetes in Children
Emergency Medicine
Summary and Comment
In a Canadian study, most children saw a doctor at least once during the 4 weeks before a new diagnosis of diabetes.
The ACCORD Lipid Study: Fenofibrate Doesn't Help
Cardiology
Summary and Comment
Free
Although triglyceride levels improved markedly with fenofibrate, incidence of adverse cardiovascular events was not affected.
The ACCORD Blood Pressure Study: What Target for High-Risk Diabetic Patients?
Cardiology
Summary and Comment
Free
Achieving systolic blood pressure levels lower than 140 mm Hg does not prevent adverse cardiovascular events.
Diabetes and Cardiovascular Events: Not a Straight Course
Cardiology
Summary and Comment
A study of two drugs for the primary prevention of diabetes yielded disappointing results.
By Harlan M. Krumholz, MD, SM
March 14, 2010
Covering:
The NAVIGATOR Study Group., N Engl J Med 2010 Mar 14
The NAVIGATOR Study Group., N Engl J Med 2010 Mar 14
Nathan DM., N Engl J Med 2010 Mar 14
More on Depression and Diabetes
Psychiatry
Summary and Comment
Even low-grade preexisting depression may increase the risk for diabetes.
By Joel Yager, MD
March 8, 2010
Covering:
Campayo A et al., Am J Psychiatry 2010 Feb 1
Cardiovascular Benefits of Statins vs. Risk for Incident Diabetes
General Medicine
Summary and Comment
Free
One additional case of incident diabetes occurred for every 255 patients who received statins for 4 years.
By Bruce Soloway, MD
March 4, 2010
Covering:
Sattar N et al., Lancet 2010 Feb 27; 375:735
Glycosylated Hemoglobin and Cardiovascular Risk in Nondiabetic Adults
General Medicine
Summary and Comment
Even within the normal range, HbA1c level correlated with diabetes risk.
By Allan S. Brett, MD
March 4, 2010
Covering:
Selvin E et al., N Engl J Med 2010 Mar 4; 362:800
Sharing Cardiovascular Risk Information with Patients
Cardiology
Summary and Comment
Patients benefit from getting their risk scores, but only if it's done repeatedly or reinforced with counseling.
By Frederick A. Masoudi, MD, MSPH
March 3, 2010
Covering:
Sheridan SL et al., Arch Intern Med 2010 Feb 8; 170:230
Ahmad T and Mora S., Arch Intern Med 2010 Feb 8; 170:227