Exercise and Glucose Control in Patients with Type 2 Diabetes
General Medicine Summary and Comment
A combination of resistance and aerobic training was better than either one alone.
ACCORD: Blood Pressure and Lipid Results
For older diabetic patients, a systolic BP target in the 130s probably is best.
ACCORD: Microvascular Outcomes
In older diabetic patients, clinical microvascular endpoints were unaffected by tight glycemic control.
New Institute of Medicine Recommendations on Vitamin D
Dermatology Summary and Comment
Free
Evidence is lacking for extraskeletal health benefits of vitamin D; most people in the U.S. and Canada have adequate serum 25-hydroxyvitamin D levels.
By Craig A. Elmets, MD
December 17, 2010
Covering:
Ross AC et al., J Clin Endocrinol Metab 2010 Nov 29
Intensive Intervention Promotes Exercise in Patients with Type 2 Diabetes
General Medicine Summary and Comment
A structured exercise program improved cardiovascular risk profiles, compared with counseling alone.
By Thomas L. Schwenk, MD
December 14, 2010
Covering:
Balducci S et al., Arch Intern Med 2010 Nov 8; 170:1794
Suicide Risk After Bariatric Surgery?
Psychiatry Summary and Comment
The long-term risk seems to increase, but psychiatric comorbidities and surgical sequelae may also be factors.
By Joel Yager, MD
December 13, 2010
Covering:
Tindle HA et al., Am J Med 2010 Nov; 123:1036
Stress-Busting Effects of Hedonic Foods
Psychiatry Summary and Comment
In this animal study, behavioral, endocrine, and cardiac measures show the stress-relieving effects of oral (but not intragastric) sucrose.
By Barbara Geller, MD
December 13, 2010
Covering:
Ulrich-Lai YM et al., Proc Natl Acad Sci U S A 2010 Nov 23; 107:20529
Acne and Acanthosis
Dermatology Summary and Comment
In Native American children, acanthosis nigricans was a specific but not a sensitive marker for insulin resistance.
By Mark V. Dahl, MD
December 3, 2010
Covering:
Nsiah-Kumi PA et al., J Natl Med Assoc 2010 Oct; 102:944
Vitamin D Receptor Activation Reduces Albuminuria in Patients with Diabetic Nephropathy
General Medicine Summary and Comment
Paricalcitol also had beneficial effects on systemic blood pressure and glomerular filtration rate.
By Bruce Soloway, MD
November 24, 2010
Covering:
de Zeeuw D et al., Lancet 2010 Nov 6; 376:1543
Preventing Type 1 Diabetes
At-risk infants who were fed hydrolyzed casein formula developed fewer diabetes-associated autoantibodies.
By Howard Bauchner, MD
November 10, 2010
Covering:
Knip M et al., N Engl J Med 2010 Nov 11; 363:1900
More Results on "Glitazones" and Fractures
General Medicine Summary and Comment
Thiazolidinedione-associated fracture risk could be a class effect.
By Allan S. Brett, MD
November 2, 2010
Covering:
Bilik D et al., J Clin Endocrinol Metab 2010 Oct; 95:4560
Hypoglycemia and Adverse Cardiovascular Outcomes: Are They Related?
General Medicine Summary and Comment
Free
A large trial demonstrated an association, but not necessarily a causal one.
By Allan S. Brett, MD
October 6, 2010
Covering:
Zoungas S et al., N Engl J Med 2010 Oct 7; 363:1410
High Intake of Green Leafy Vegetables Is Associated with Lower Risk for Type 2 Diabetes
General Medicine Summary and Comment
Eat your spinach.
Once-Weekly Exenatide vs. Sitagliptin or Pioglitazone for Type 2 Diabetes
General Medicine Summary and Comment
Free
Long-acting exenatide lowered glycosylated hemoglobin levels more than the other two drugs did.
By Bruce Soloway, MD
August 26, 2010
Covering:
Bergenstal RM et al., Lancet 2010 Aug 7; 376:431
Does Vitamin C and E Supplementation Protect Against Preeclampsia in Women with Type 1 Diabetes?
Women's Health Summary and Comment
Only in those study participants who had low baseline vitamin status.
By Anna Wald, MD, MPH
August 19, 2010
Covering:
McCance DR et al., Lancet 2010 Jul 24; 376:259
A New Development: Sensor-Augmented Insulin-Pump Therapy
General Medicine Summary and Comment
Promising results for a combination device
By Thomas L. Schwenk, MD
July 27, 2010
Covering:
Bergenstal RM et al., N Engl J Med 2010 Jul 22; 363:311
Wolpert HA., N Engl J Med 2010 Jul 22; 363:383
Blood Pressure Control in Patients with Diabetes and Coronary Artery Disease
General Medicine Summary and Comment
Free
No benefit for lowering BP to <130/80 mm Hg
If Your Stomach Is Bigger, Is Your Brain Smaller?
Psychiatry Summary and Comment
Free
Visceral fat is associated with smaller brain volume.
Microvascular Outcomes in the ACCORD Trial
General Medicine Summary and Comment
Intensive glycemic control did not lower the incidence of microvascular adverse outcomes.
Retinopathy in the ACCORD Trial
General Medicine Summary and Comment
Findings from the ACCORD Eye Study are not straightforward.
By Allan S. Brett, MD
July 13, 2010
Covering:
The ACCORD Study Group and ACCORD Eye Study Group., N Engl J Med 2010 Jul 15; 363:233
Weekly Exenatide Equals Daily Glargine Insulin for Glycemic Control
General Medicine Summary and Comment
And patients also lose weight with exenatide.
By Bruce Soloway, MD
July 13, 2010
Covering:
Diamant M et al., Lancet 2010 Jun 26; 375:2234
Aspirin for Primary Prevention in Patients with Diabetes
General Medicine Summary and Comment
Free
Recommendations from three professional organizations
By Allan S. Brett, MD
July 8, 2010
Covering:
Pignone M et al., Circulation 2010 Jun 22; 121:2694
Obesity Raises Risk for Diabetes in Older People
General Medicine Summary and Comment
Weight gain after age 50, just like earlier in life, raises risk.
More Bad News for Rosiglitazone
Cardiology Summary and Comment
Free
Mounting evidence of adverse cardiovascular effects continues to erode justification for its use.
By Frederick A. Masoudi, MD, MSPH
June 30, 2010
Covering:
Graham DJ et al., JAMA 2010 Jun 28
Juurlink DN., JAMA 2010 Jun 28
Nissen SE and Wolski K., Arch Intern Med 2010 Jun 28
Rice Intake and Risk for Developing Type 2 Diabetes
General Medicine Summary and Comment
Substituting brown rice for white rice might lower relative risk for diabetes.
