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Diabetes: Archives

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Items 151-175 of 301 are shown

Gestational Hyperglycemia: Continuum of Risk, Choices for Treatment

Likelihood of adverse pregnancy outcomes increased in proportion to maternal glucose levels; metformin for gestational diabetes was not inferior to insulin.

  • By Ann J. Davis, MD
  • May 7, 2008
  • Covering:
    • The HAPO Study Cooperative Research Group., N Engl J Med 2008 May 8; 358:1991
    • Rowan JA et al., N Engl J Med 2008 May 8; 358:2003
    • Ecker JL and Greene MF., N Engl J Med 2008 May 8; 358:2061

How Low Should We Go (with BP and Cholesterol in Diabetic Patients)?

Lower might be better, but more clinical data are needed.

Does Early Vitamin D Supplementation Prevent Type 1 Diabetes?

Findings from a meta-analysis suggest that vitamin D supplementation in infancy lowers risk for developing type 1 diabetes.

Basal Insulin Is as Effective as Preprandial Insulin in Type 2 Diabetes

They have similar effects on HbA1c levels, but patients prefer basal insulin.

  • By Bruce Soloway, MD
  • April 22, 2008
  • Covering:
    • Bretzel RG et al., Lancet 2008 Mar 29; 371:1073

An ACE Inhibitor, an ARB, or Both for Patients at High Vascular Risk?

An ARB was as efficacious as an ACE inhibitor, but combination therapy failed to show any advantages.

  • By Jamaluddin Moloo, MD, MPH
  • April 17, 2008
  • Covering:
    • Yusuf S et al. for the ONTARGET Investigators., N Engl J Med 2008 Apr 10; 358:1547

Can Metformin Attenuate Olanzapine-Induced Weight Gain?

Adding an antihyperglycemic agent may prevent weight gain and metabolic syndrome in patients with new-onset schizophrenia.

  • By Joel Yager, MD
  • April 14, 2008
  • Covering:
    • Wu R-R et al., Am J Psychiatry 2008 Mar; 165:352

Aggressive Treatment of High LDL Levels and Hypertension in Patients with Diabetes

Three-year results from SANDS supply much-needed information but no definitive answer to the question of how low to set targets in primary prevention of CVD.

Disturbances of Glucose Metabolism in Depression

Whole-body glucose disposal is impaired in depressed patients.

  • By Joel Yager, MD
  • April 7, 2008
  • Covering:
    • Schweiger U et al., Psychosom Med 2008 Feb/Mar; 70:170

Slowing Progression of Atherosclerosis in Diabetic Patients

Pioglitazone outperformed glimepiride in a preliminary trial.

Pioglitazone vs. Glimepiride for Atherosclerosis in Diabetes

Pioglitazone comes out on top in this randomized trial, but we still need outcomes data.

  • By Harlan M. Krumholz, MD, SM
  • March 31, 2008
  • Covering:
    • Nissen SE et al. for the PERISCOPE Investigators., JAMA 2008 Apr 2; 299:1561

Choice of Antihypertensive Agents for Patients with Metabolic Syndrome: ALLHAT Results

Diuretics should continue to be first-line agents for treating patients with hypertension.

"Anodyne Therapy" for Diabetic Neuropathy — No Benefit

A device for delivery of monochromatic infrared energy was no more effective than sham treatment.

  • By Allan S. Brett, MD
  • March 6, 2008
  • Covering:
    • Lavery LA et al., Diabetes Care 2008 Feb; 31:316

Blood Pressure and Risk for Developing Diabetes

Elevated BP as well as BP escalations over time — even if only in the high-normal range — puts women at increased risk for diabetes.

  • By Marian C. Limacher, MD
  • February 14, 2008
  • Covering:
    • Conen D et al., Eur Heart J 2007 Dec; 28:2937
    • Nilsson PM., Eur Heart J 2007 Dec; 28:2832

Glucose-Control Arm of ACCORD Trial Halted Early

Increased mortality associated with aggressive glucose reduction raises safety concerns.

Marijuana and Periodontal Disease

Cannabis smoking could be an independent risk factor, in addition to tobacco.

  • By Thomas L. Schwenk, MD
  • February 12, 2008
  • Covering:
    • Thomson WM et al., JAMA 2008 Feb 6; 299:525
    • Hujoel PP., JAMA 2008 Feb 6; 299:574

Multifactorial Treatment of Type 2 Diabetes with Microalbuminuria

Intensive treatment lowered risks for morbid diabetes complications, all-cause death, and death from cardiovascular disease.

  • By Paul S. Mueller, MD, MPH, FACP
  • February 6, 2008
  • Covering:
    • Gæde P et al., N Engl J Med 2008 Feb 7; 358:580

Update on Diabetic Neuropathy

Clinical results have disappointed, but new developments are promising.

  • By James W. Albers, MD, PhD
  • February 5, 2008
  • Covering:
    • Zochodne DW., Muscle Nerve 2007 Aug; 36:144

Diet and Diabetes Risk in U.S. Black Women and Chinese Women: Glycemic Index and Load

Diabetes risk was lower in black women who ate more cereal fiber and in Chinese women who ate less rice.

  • By Diane E. Judge, APN/CNP
  • January 17, 2008
  • Covering:
    • Krishnan S et al., Arch Intern Med 2007 Nov 26; 167:2304
    • Villegas R et al., Arch Intern Med 2007 Nov 26; 167:2310

Moderate Drinking Might Improve Fasting Glucose in People with Diabetes

A benefit was reported for one glass of wine with dinner.

Inadequate Blood Pressure Control in U.S. Adults

Patients at risk for cardiovascular events are likely to have high blood pressure, even when treated for hypertension.

  • By Joel M. Gore, MD
  • January 9, 2008
  • Covering:
    • Wong ND et al., Arch Intern Med 2007 Dec 10; 167:2431

Thiazolidinediones and Cardiovascular Risk in Older Patients

Population-based data confirm risk with rosiglitazone, even in patients without prior cardiac disease.

Rosiglitazone: Unclear Evidence, Uncertain Practice

Does rosiglitazone significantly increase risk for cardiovascular death or MI? It depends on how the data are analyzed . . .

More Safety Data on Thiazolidinediones

Rosiglitazone raises rates of heart failure, MI, and mortality in older diabetic patients, according to a large, retrospective study.

  • By JoAnne M. Foody, MD
  • December 26, 2007
  • Covering:
    • Lipscombe LL et al., JAMA 2007 Dec 12; 298:2634

Fitness and Mortality in Older Adults

Physical activity, not body composition, may be the key to reducing risk.

In Clinical Practice, Drug-Eluting Stents Outperform Bare-Metal Stents

In a population-based cohort, DES resulted in fewer repeat revascularizations than BMS, with no difference in rates of death or MI at 1 year.

  • By Howard C. Herrmann, MD
  • December 26, 2007
  • Covering:
    • Abbott JD et al., J Am Coll Cardiol 2007 Nov 20; 50:2029
    • Büttner HJ and Neumann F-J., J Am Coll Cardiol 2007 Nov 20; 50:2037
Items 151-175 of 301 are shown

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