Metabolic Risk Factor for Complications in Type 1 Diabetes
General Medicine Summary and Comment
A dearth of advanced glycation end products might distinguish complication-free diabetic patients from their peers.
Quality of Life in the ACCORD Trial
General Medicine Summary and Comment
Intensive glycemic control did not improve self-reported physical or mental health.
By Allan S. Brett, MD
May 10, 2011
Covering:
Anderson RT et al., Diabetes Care 2011 Apr; 34:807
Guidelines: Extracranial Carotid and Vertebral Artery Disease
Neurology Clinical Practice Guideline Watch
Free
Experts address the appropriate use of contemporary imaging and revascularization techniques and identify important gaps in the evidence base to guide future research.
Treatment of Painful Diabetic Neuropathy
General Medicine Clinical Practice Guideline Watch
Free
A new guideline and results of a new randomized trial might be helpful for clinicians.
By Allan S. Brett, MD
May 5, 2011
Covering:
Bril V et al., Neurology 2011 Apr 11
Kaur H et al., Diabetes Care 2011 Apr; 34:818
HIV Independently Associated with Heart Failure Risk
Cardiology Summary and Comment
Observational data suggest that heightened vigilance and aggressive risk-factor management are warranted to prevent HF in HIV-infected individuals.
By JoAnne M. Foody, MD
May 4, 2011
Covering:
Butt AA et al., Arch Intern Med 2011 Apr 25; 171:737
Treatment of Painful Diabetic Neuropathy: New Evidence-Based Guidelines
Neurology Clinical Practice Guideline Watch
Only pregabalin gets a level A indication for treatment of painful diabetic neuropathy.
By Paola Sandroni, MD, PhD
April 26, 2011
Covering:
Bril V et al., Neurology 2011 Apr 11
Pioglitazone to Prevent Progression to Diabetes
General Medicine Summary and Comment
This drug lowered risk for progression but raised risk for edema and weight gain.
Value of GFR and Albuminuria in Predicting Cardiovascular Outcomes
General Medicine Summary and Comment
Free
Glomerular filtration rate and albuminuria did not add value to traditional risk factors.
Rosiglitazone vs. Pioglitazone — What Are the Odds?
General Medicine Summary and Comment
Free
Odds for myocardial infarction, congestive heart failure, and overall mortality were higher with rosiglitazone.
By Paul S. Mueller, MD, MPH, FACP
April 7, 2011
Covering:
Loke YK et al., BMJ 2011 Mar 17; 342:d1309
Montori VM and Shah ND., BMJ 2011 Mar 17; 342:d1354
Glycemic Control in Hospitalized Patients: Hold On Loosely?
Hospital Medicine Clinical Practice Guideline Watch
A clinical guideline from the American College of Physicians recommends against intensive insulin therapy.
The RABBIT 2 Surgery Study: Should We Stop Sliding?
Hospital Medicine Summary and Comment
Basal-bolus insulin bests sliding-scale insulin again, but many questions remain.
Group Visits for Patients with Diabetes
General Medicine Summary and Comment
Physician-led groups focused on specific goals to improve glycemic control.
Prevention of Microalbuminuria with Olmesartan
General Medicine Summary and Comment
Free
This drug delayed onset slightly but did not change overall incidence.
Guidelines: Extracranial Carotid and Vertebral Artery Disease
Cardiology Clinical Practice Guideline Watch
Free
Experts address the appropriate use of contemporary imaging and revascularization techniques and identify important gaps in the evidence base to guide future research.
By Beat J. Meyer, MD
March 16, 2011
Covering:
Brott TG et al., J Am Coll Cardiol 2011 Feb 22; 57:1002
More Follow-Up from the ACCORD Trial
General Medicine Summary and Comment
Free
Once again, intensive glycemic treatment cannot be recommended for older patients with long-standing type 2 diabetes.
By Allan S. Brett, MD
March 2, 2011
Covering:
The ACCORD Study Group., N Engl J Med 2011 Mar 3; 364:818
Exenatide in Conjunction with Basal Insulin for Diabetes
General Medicine Summary and Comment
The combination is safe.
By Jamaluddin Moloo, MD, MPH
February 17, 2011
Covering:
Buse JB et al., Ann Intern Med 2011 Jan 18; 154:103
Nathan DM., Ann Intern Med 2011 Jan 18; 154:131
Association Between Enterovirus Infection and Type 1 Diabetes
General Medicine Summary and Comment
The clinically significant link probably involves viruses, pancreatic islet cells, and patients' immune systems and genotypes.
By Paul S. Mueller, MD, MPH, FACP
February 15, 2011
Covering:
Yeung W-CG et al., BMJ 2011 Feb 3; 342:d35
Hober D and Sane F., BMJ 2011 Feb 3; 342:c7072
Cardiovascular Risk Assessment in Asymptomatic Adults
Cardiology Clinical Practice Guideline Watch
Free
<$EMPH_O>New guidelines reflect a conservative approach.<$EMPH_C>
By JoAnne M. Foody, MD
February 9, 2011
Covering:
Greenland P et al., J Am Coll Cardiol 2010 Dec 14/21; 56:e50
Diabetes Adversely Affects Breast Cancer Outcomes
Women's Health Summary and Comment
All-cause mortality was higher among women with diabetes and breast cancer than among their nondiabetic counterparts; breast cancer diagnosis and treatment differed for women with versus without diabetes.
By Diane E. Judge, APN/CNP
February 3, 2011
Covering:
Erickson K et al., J Clin Oncol 2011 Jan 1; 29:54
Peairs KS et al., J Clin Oncol 2011 Jan 1; 29:40
Use of Hemoglobin A1c to Diagnose Diabetes
General Medicine Summary and Comment
Cutoffs for glycosylated hemoglobin and fasting glucose levels don't identify the same people as having diabetes.
By Allan S. Brett, MD
February 1, 2011
Covering:
Lipska KJ et al., J Clin Endocrinol Metab 2010 Dec; 95:5289
Cohen RM et al., J Clin Endocrinol Metab 2010 Dec; 95:5203
Depression and Diabetes — A Bad Combination
Psychiatry Summary and Comment
In the Nurses' Health Study, both conditions increased all-cause and cardiovascular mortality, and the combination was worse than either condition alone.
By Steven Dubovsky, MD
January 31, 2011
Covering:
Pan A et al., Arch Gen Psychiatry 2011 Jan; 68:42
Pancreatitis, Diabetes, and Newer Antidiabetic Drugs
General Medicine Summary and Comment
Sitagliptin and exenatide use did not raise risk for pancreatitis, beyond that incurred from diabetes itself.
By Allan S. Brett, MD
January 20, 2011
Covering:
Garg R et al., Diabetes Care 2010 Nov; 33:2349
Gonzalez-Perez A et al., Diabetes Care 2010 Dec; 33:2580
Coordinated Care of Depression and Chronic Physical Illness
General Medicine Summary and Comment
Significant improvements were realized in risk factor control, quality of life, and satisfaction with care.
Diabetes Screening During and After Pregnancy: We Must Do Better
Women's Health Summary and Comment
Free
New screening criteria translated to higher rates of gestational diabetes; fewer than 20% of women with gestational diabetes underwent postpartum diabetes testing.
By Wendy S. Biggs, MD
January 13, 2011
Covering:
Blatt AJ et al., Obstet Gynecol 2011 Jan; 117:61
Inhaled Corticosteroids Might Provoke Diabetes
General Medicine Summary and Comment
In an observational study, diabetes was more likely to develop in current steroid users.
