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Diabetes: Archives

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Items 401-425 of 526 are shown

Glucose-Insulin-Potassium Infusion May Cause Early Harm After STEMI

New analyses reveal a mortality risk in the first 3 days and confirm a lack of longer-term benefit.

Are We Losing the War Against Heart Disease?

The once-rapid decline in the heart disease death rate has slowed significantly among young adults.

  • By JoAnne M. Foody, MD
  • November 28, 2007
  • Covering:
    • Ford ES and Capewell S., J Am Coll Cardiol 2007 Nov 27; 50:2128
    • Greenland P and Lloyd-Jones D., J Am Coll Cardiol 2007 Nov 27; 50:2133

Sirolimus-Eluting Stents Outperform Bare-Metal Stents in Patients with Diabetes

At 1 year of follow-up, results of the SCORPIUS study favored SES for both efficacy and safety.

  • By Howard C. Herrmann, MD
  • November 28, 2007
  • Covering:
    • Baumgart D et al., J Am Coll Cardiol 2007 Oct 23; 50:1627

Comparative Effectiveness of ACE Inhibitors and Angiotensin-Receptor Blockers for Hypertension

A meta-analysis revealed no between-class difference in effectiveness but a dearth of clinical outcomes data.

  • By Joel M. Gore, MD
  • November 28, 2007
  • Covering:
    • Matchar DB et al., Ann Intern Med 2007 Nov 5
    • Parfrey PS., Ann Intern Med 2007 Nov 5

Renin-Angiotensin System Inhibitors for Proteinuria: Monotherapy or Combination Therapy?

Monotherapy with either an ARB or an ACE inhibitor effectively reduces proteinuria; combining the two may pack even more of a punch.

  • By Joel M. Gore, MD
  • November 28, 2007
  • Covering:
    • Kunz R et al., Ann Intern Med 2007 Nov 5
    • Parfrey PS., Ann Intern Med 2007 Nov 5

Pelvic Floor Dysfunction, Diabetes, and Obesity

Obese diabetic women were at highest risk for pelvic floor disorders.

Coronary Heart Disease Linked to Colorectal Tumors

Evidence from a prospective study implicates common risk factors, notably metabolic syndrome and smoking.

  • By JoAnne M. Foody, MD
  • October 31, 2007
  • Covering:
    • Chan AOO et al., JAMA 2007 Sep 26; 298:1412

Omega-3 Fatty Acids May Reduce the Risk for Islet Cell Decline in Children

Analyses of intake and biomarker data strengthen the evidence for a protective effect against type I diabetes.

  • By JoAnne M. Foody, MD
  • October 31, 2007
  • Covering:
    • Norris JM et al., JAMA 2007 Sep 26; 298:1420

Initiating Insulin in Type 2 Diabetes – The "4-T" Trial

First-year comparisons among prandial, biphasic, and basal insulins reveal tradeoffs in efficacy and safety.

  • By Allan S. Brett, MD
  • October 23, 2007
  • Covering:
    • Holman RR et al., N Engl J Med 2007 Oct 25; 357:1716
    • McMahon GT and Dluhy RG., N Engl J Med 2007 Oct 25; 357:1759

In a New Meta-Analysis, Thiazolidinediones Increase CHF but Not Cardiac Death

The results aren’t inconsistent with previous meta-analyses.

  • By Bruce Soloway, MD
  • October 11, 2007
  • Covering:
    • Lago RM et al., Lancet 2007 Sep 29; 370:1129
    • Cleland JGF and Atkin SL., Lancet 2007 Sep 29; 370:1103
    • Montori VM et al., Lancet 2007 Sep 29; 370:1104
    • Lancet 2007 Sep 29; 370:1101

Thiazolidinediones and Increased MI Risk: A Class Effect?

New meta-analyses support an increased risk for MI with rosiglitazone, but not with pioglitazone.

  • By JoAnne M. Foody, MD
  • October 10, 2007
  • Covering:
    • Lincoff AM et al., JAMA 2007 Sep 12; 298:1180
    • Singh S et al., JAMA 2007 Sep 12; 298:1189

Routine Use of Perindopril and Indapamide in Type 2 Diabetes

A simple and practical strategy emerges as an ADVANCE in the prevention of vascular events due to hypertension.

  • By Beat J. Meyer, MD
  • October 10, 2007
  • Covering:
    • Patel A et al. for the ADVANCE Collaborative Group., Lancet 2007 Sep 8; 370:829

Optimal Hemoglobin A1c Targets: Guidance from the ACP

The core recommendation is not new, but the ACP commendably focuses on individualizing goals for glycemic control.

Which Antidiabetic Drugs Are Safest for People with Diabetes and Heart Failure?

In this systematic review, metformin was associated with the best outcomes.

Aerobic Exercise and Resistance Training Benefit Glycemic Control

Physical activity — especially aerobic exercise and resistance training combined — can significantly lower hemoglobin A1c levels in patients with type 2 diabetes.

Screening and Follow-Up for Gestational Diabetes

High-risk individuals require both initial screening and repeated testing during and after pregnancy.

The Questions Continue About Thiazolidinediones’ Safety

A new meta-analysis shows an elevated risk for congestive HF but no increase in cardiovascular death rate with either rosiglitazone or pioglitazone

  • By Beat J. Meyer, MD
  • September 28, 2007
  • Covering:
    • Lago RM et al., Lancet 2007 Sep 29; 370:1129
    • Cleland JGF and Atkin SL., Lancet 2007 Sep 29; 370:1103
    • Montori VM et al., Lancet 2007 Sep 29; 370:1104
    • Lancet 2007 Sep 29; 370:1101

Fitness, Obesity, and Insulin Resistance

Exercise decreased insulin resistance despite no changes in fat or lean body mass.

Thiazolidinediones and Heart Disease Risk

Pioglitazone had a mixed risk profile, and rosiglitazone increased risk for ischemic heart disease, but neither increased mortality.

  • By Thomas L. Schwenk, MD
  • September 11, 2007
  • Covering:
    • Lincoff AM et al., JAMA 2007 Sep 12; 298:1180-8
    • Singh S et al., JAMA 2007 Sep 12; 298:1189-95
    • Solomon DH and Winkelmayer WC., JAMA 2007 Sep 12; 298:1216-8

Trim Weight, Reduce Apnea and Metabolic Abnormalities?

Weight loss leads to proportionately fewer symptoms of sleep apnea, and apnea appears to be associated with diabetes and hypertriglyceridemia.

  • By David P. White, MD
  • September 11, 2007
  • Covering:
    • Grunstein RR et al., Sleep 2007 Jun 1; 30:703-10

Diabetes Increases Short-Term Mortality Risk in Patients with Acute Coronary Syndromes

This is true for people with unstable angina, NSTEMI, and STEMI.

Eating Wisely Deters Diabetes

Women with healthy diets as indicated by high Alternate Healthy Eating Index scores had reduced risk for type 2 diabetes.

Maternal Obesity Increases Risk for Birth Defects

Maternal obesity and overweight increased risk for many birth defects, but obesity decreased risk for gastroschisis.

Weight Gain with Olanzapine: Does Metformin Help?

Patients lost a little, but not enough to make a difference.

  • By Jonathan Silver, MD
  • August 27, 2007
  • Covering:
    • Baptista T et al., Schizophr Res 2007 Jul; 93:99-108

Acute MI as a Marker for Diabetes Risk

High rates of impaired fasting glucose and diabetes after MI suggest that MI could be a prediabetes risk equivalent.

  • By Beat J. Meyer, MD
  • August 23, 2007
  • Covering:
    • Mozaffarian D et al., Lancet 2007 Aug 25; 370:667-75
    • Opie LH., Lancet 2007 Aug 25; 370:634-5
Items 401-425 of 526 are shown

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