Diabetes and Mortality in Men with Prostate Cancer
Prostate cancer patients with diabetes did not have higher risk for prostate cancer mortality than did prostate cancer patients without diabetes.
Improving Glycosylated Hemoglobin Levels in Children with Diabetes
Parents often help young children manage their disease, but management during the adolescent years is difficult.
By Howard Bauchner, MD
October 1, 2008
Covering:
The Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group., N Engl J Med 2008 Oct 2; 359:1464
Bicarbonate vs. Saline for Preventing Contrast-Induced Nephropathy
Cardiology Summary and Comment
In a randomized study, bicarbonate plus <$EMPH_O>N<$EMPH_C>-acetylcysteine was no more effective than saline plus <$EMPH_O>N<$EMPH_C>-acetylcysteine.
Continuous Glucose Monitoring in Type 1 Diabetes
General Medicine Summary and Comment
Continuous monitoring helped lower HbA1c levels in patients who were older than 24, but not in children, adolescents, or younger adults.
By Allan S. Brett, MD
September 30, 2008
Covering:
The Juvenile Diabetes Research Foundation Continuous Glucose Monitoring Study Group., N Engl J Med 2008 Oct 2; 359:1464
Birth Defects and Maternal Diabetes Mellitus: All Is Not Sweetness
Pregestational DM is associated with a broader range of birth defects than is gestational DM, and the association between gestational DM and birth defects is limited mostly to overweight and obese women.
Who Needs Stem Cells? Reprogramming One Adult Cell Directly into Another
General Medicine Summary and Comment
Insertion of three genes transformed adult pancreatic exocrine cells into functional β-cells in mice.
Elevated BP Predicts Development of Retinopathy in Adolescents with Type 1 Diabetes
General Medicine Summary and Comment
Adolescents with blood pressure in the top tenth for their age group were at significant risk for retinopathy.
Effects of Diabetes Can Go Beyond Mom
Women's Health Summary and Comment
Free
Pregestational diabetes was associated with a wider range of birth defects than was gestational diabetes.
Diet’s Effect on Diabetes Risk: Is It the Fat? Or the Carbs?
Women's Health Summary and Comment
In older women, lowering fat intake alone did not affect diabetes risk; in black women, sugar-sweetened drinks were associated with excess diabetes risk.
By Diane E. Judge, APN/CNP
September 18, 2008
Covering:
Tinker LF et al., Arch Intern Med 2008 Jul 28; 168:1500
Palmer JR et al., Arch Intern Med 2008 Jul 28; 168:1487
Feinglos MN and Totten SE., Arch Intern Med 2008 Jul 28; 168:1485
Telmisartan in ACE-Inhibitor–Intolerant Patients: A Disappointment
Cardiology Summary and Comment
In a placebo-controlled trial, researchers found an unexpectedly low, statistically nonsignificant reduction in clinical outcomes.
By Beat J. Meyer, MD
September 17, 2008
Covering:
The TRANSCEND Investigators., Lancet 2008 August 31
Glucose Control in the ICU: More Studies, Ongoing Uncertainty
General Medicine Summary and Comment
Which ICU patients benefit from low glucose targets? We still don’t know.
By Thomas L. Schwenk, MD , and Allan S. Brett, MD
September 16, 2008
Covering:
Soylemez Wiener R et al., JAMA 2008 Aug 27; 300:933
Treggiari MM et al., Crit Care 2008 ; 12:R29
Egi M et al., Crit Care Med 2008 Aug; 36:2249
Sweet and Salty: Hemoglobin A1c and Cardiovascular Events in Heart Failure
Cardiology Summary and Comment
In a CHARM substudy, increased HbA1c levels were strongly associated with adverse outcomes in heart failure patients, whether or not they had diabetes.
By William T. Abraham, MD
September 10, 2008
Covering:
Gerstein HC et al. for the CHARM program investigators., Arch Intern Med 2008 Aug 11; 168:1699
Recertification Scores Correlate with Quality of Care
Dermatology Summary and Comment
Some indicators of quality of care were positively associated with top scores on the internal medicine recertification exam.
By Jeffrey P. Callen, MD
September 5, 2008
Covering:
Holmboe ES et al., Arch Intern Med 2008 Jul 14; 168:1396
Landon BE., Arch Intern Med 2008 Jul 14; 168:1365
Arsenic Exposure and Risk for Type 2 Diabetes
General Medicine Summary and Comment
Inorganic, but not organic, arsenic exposure is associated with elevated risk.
By Thomas L. Schwenk, MD
September 4, 2008
Covering:
Navas-Acien A et al., JAMA 2008 Aug 20; 300:814
Kile ML and Christiani DC., JAMA 2008 Aug 20; 300:845
How Fat Am I? Or, How Am I Fat?
Cardiology Summary and Comment
Two new studies address how obesity relates to cardiovascular risk factors.
By JoAnne M. Foody, MD
September 3, 2008
Covering:
Wildman RP et al., Arch Intern Med 2008 Aug 11; 168:1617
Stefan N et al., Arch Intern Med 2008 Aug 11; 168:1609
Combination of ACE Inhibitor and ARB Offers Little Advantage for Renal Function
General Medicine Summary and Comment
Free
Monotherapy was more effective in preserving renal function.
By Bruce Soloway, MD
September 2, 2008
Covering:
Mann JFE et al., Lancet 2008 Aug 16; 372:547
Translating Hemoglobin A1c into Average Glucose Values
General Medicine Summary and Comment
Free
In stable diabetic patients, each percentage point of HbA1c corresponded to about a 29 mg/dL increment in estimated average glucose.
By Allan S. Brett, MD
August 28, 2008
Covering:
Nathan DM et al., Diabetes Care 2008 Aug; 31:1473
Hyperinsulinism in Daughters of Mothers with Polycystic Ovary Syndrome
General Medicine Summary and Comment
The authors suggest that hyperinsulinism may be the first and most common abnormality in the daughters of mothers with PCOS.
By Robert W. Rebar, MD
August 28, 2008
Covering:
Kent SC et al., J Clin Endocrinol Metab 2008 May; 93:1662
Renin-Angiotensin Inhibition for Renoprotection in Patients at High Cardiovascular Risk
Cardiology Summary and Comment
Monotherapy with an ACE inhibitor or an ARB improved major renal outcomes, but combination therapy worsened them, despite a greater reduction in proteinuria.
By Beat J. Meyer, MD
August 27, 2008
Covering:
Mann JFE et al., Lancet 2008 Aug 16; 372:547
New Recommendations for Diabetes Screening
Women's Health Practice Watch
USPSTF recommendations support diabetes screening for asymptomatic adults with blood pressure >135/80 mm Hg.
Lipid Screening in Childhood — New Recommendations from the AAP
Cardiology Clinical Practice Guideline Watch
Controversial new recommendations advocate wider screening and use of statins in children.
Metabolic Syndrome Adds Little to Prediction of Diabetes and CVD
General Medicine Summary and Comment
The metabolic syndrome was defined to aid in predicting and preventing vascular events and diabetes, but other readily available data are more powerful predictors.
By Bruce Soloway, MD
July 29, 2008
Covering:
Sattar N et al., Lancet 2008 Jun 7; 371:1927
Kahn R., Lancet 2008 Jun 7; 371:1892
Effect of DKA on QTc Prolongation in Children Might Be Mediated by Ketosis, Not Electrolyte Abnormalities
Emergency Medicine Summary and Comment
Free
Possible cardiac effects of ketosis make cardiac monitoring of children with DKA essential.
USPSTF Recommends Screening for Diabetes in Adults with Elevated Blood Pressure
General Medicine Clinical Practice Guideline Watch
Evidence was insufficient to recommend screening of asymptomatic people with lower blood pressure.
By Richard Saitz, MD, MPH, FACP, FASAM
July 24, 2008
Covering:
Norris SL et al., Ann Intern Med 2008 Jun 3; 148:855
U.S. Preventive Services Task Force., Ann Intern Med 2008 Jun 3; 148:846
Management of Adolescents with Type 2 Diabetes
Pediatrics and Adolescent Medicine Clinical Practice Guideline Watch
A summary of recommendations from the U.K. relevant to adolescents
By Howard Bauchner, MD
July 23, 2008
Covering:
National Institute for Health and Clinical Excellence.,
