No Need to Treat Asymptomatic Bacteriuria in Women with Diabetes
Infectious Diseases Summary and Comment
Asymptomatic bacteriuria in women with diabetes doesn’t affect renal function or blood pressure.
By Daniel J. Diekema, MD, MS
November 29, 2006
Covering:
Meiland R et al., Arch Intern Med 2006 Nov 13; 166:2222-7
Can We Cure Diabetes?
Islet cell transplantation has come a long way but has further to go.
By Howard Bauchner, MD
November 8, 2006
Covering:
Shapiro AM et al., N Engl J Med 2006 Sep 28; 355:1318-30
Bromberg JS and LeRoith D., N Engl J Med 2006 Sep 28; 355:1372-4
ACE Inhibition for Preventing Diabetes: Still Just a DREAM
Cardiology Summary and Comment
Free
Ramipril fell short in a large, randomized, placebo-controlled trial.
By Harlan M. Krumholz, MD, SM
October 25, 2006
Covering:
The DREAM Trial Investigators., N Engl J Med 2006 Oct 12; 355:1551-62
Ingelfinger JR and Solomon CG., N Engl J Med 2006 Oct 12; 355:1608-10
Rosiglitazone Tested for Diabetes Prevention
Cardiology Summary and Comment
Despite some advantages of the drug over placebo, lifestyle changes should remain the gold standard for prevention of type 2 diabetes.
By Beat J. Meyer, MD
October 25, 2006
Covering:
The DREAM Trial Investigators., Lancet 2006 Sep 23; 368:1096-105
Tuomilehto J and Wareham N., Lancet 2006 Oct 7; 368:1218-9
A Wake-Up Call About Medication Nonadherence
Cardiology Summary and Comment
Studies documented remarkable associations between medication nonadherence and increased mortality risk.
By JoAnne M. Foody, MD
October 25, 2006
Covering:
Ho PM et al., Arch Intern Med 2006 Sep 25; 166:1836-41
Ho PM et al., Arch Intern Med 2006 Sep 25; 166:1842-7
Tarn DM et al., Arch Intern Med 2006 Sep 25; 166:1855-62
O’Connor PJ., Arch Intern Med 2006 Sep 25; 166:1802-4
Diabetes and Heart Disease in Men Who Receive Androgen-Deprivation Therapy
Androgen-deprivation therapy is associated with risk for diabetes, heart disease, and osteoporosis, according to a large observational study.
By Robert Dreicer, MD, FACP
October 11, 2006
Covering:
Keating NL et al., J Clin Oncol 2006 Sep 20; 24:4448-56
Rosiglitazone, but Not Ramipril, Prevents Progression to Diabetes in Patients at Risk
General Medicine Summary and Comment
Free
The effect of rosiglitazone is similar to that reported for lifestyle changes.
By Bruce Soloway, MD
October 12, 2006
Covering:
DREAM (Diabetes REduction Assessment with ramipril and rosiglitazone Medication) Trial Investigators., Lancet 2006 Sep 23; 368:1096-105
The DREAM Trial Investigators., N Engl J Med 2006 Oct 12; 355:1551-62
Preventing Progression from Impaired Glucose Tolerance to Diabetes
General Medicine Summary and Comment
Free
Overweight patients with impaired glucose tolerance lowered their absolute 3-year risk for diabetes from about 35% to 15% by losing 5 kg.
By Allan S. Brett, MD
October 5, 2006
Covering:
Hamman RF et al., Diabetes Care 2006 Sep; 29:2102-7
Blood Glucose Variability and Mortality in Critically Ill Patients
General Medicine Summary and Comment
An observational study suggests that blood glucose variability predicts ICU mortality about as accurately as absolute glucose levels do.
By Allan S. Brett, MD
September 14, 2006
Covering:
Egi M et al., Anesthesiology 2006 Aug; 105:244-52
Is Self-Monitoring of Blood Glucose Helpful in Type 2 Diabetes?
General Medicine Summary and Comment
Free
This practice does not appear to improve glycemic control for non–insulin-treated patients.
By Allan S. Brett, MD
August 31, 2006
Covering:
Davis WA et al., Diabetes Care 2006 Aug; 29:1764-70
Can Psychological Interventions Improve Glycemic Control in Type 1 Diabetes?
General Medicine Summary and Comment
Cognitive behavioral therapy techniques are modestly effective in children and adolescents with diabetes.
By Keith I. Marton, MD
August 29, 2006
Covering:
Winkley K et al., BMJ 2006 Jul 8; 333:65-8
Early Onset of Type 2 Diabetes and End-Stage Renal Disease
Patients with youth-onset diabetes were more likely than those with older-onset diabetes to develop end-stage renal disease.
By F. Bruder Stapleton, MD
August 23, 2006
Covering:
Pavkov ME et al., JAMA 2006 Jul 26; 296:421-6
Does Atorvastatin Prevent Cardiovascular Events Among Diabetics?
General Medicine Summary and Comment
In this randomized trial, the formal answer was no, but several aspects of the study might have blunted its ability to show a significant benefit for atorvastatin.
By Jamaluddin Moloo, MD, MPH
August 17, 2006
Covering:
Knopp RH et al., Diabetes Care 2006 Jul; 29:1478-85
Pass the Yogurt, Please
Women's Health Summary and Comment
Risk for diabetes decreased as dairy consumption increased.
By Diane E. Judge, APN/CNP
August 10, 2006
Covering:
Liu S et al., Diabetes Care 2006 Jul; 29:1579-84
Mediterranean vs. Low-Fat Diet
Cardiology Summary and Comment
These two types of diets were compared in a short-term trial involving asymptomatic patients at high risk for cardiovascular disease.
By Joel M. Gore, MD
August 2, 2006
Covering:
Estruch R et al. for the PREDIMED Study Investigators., Ann Intern Med 2006 Jul 4; 145:1-11
As a Cardiac Risk Factor, Is Diabetes Always a Coronary Equivalent?
General Medicine Summary and Comment
Having diabetes appears to be roughly equivalent to aging 15 years.
By Bruce Soloway, MD
August 1, 2006
Covering:
Booth GL et al., Lancet 2006 Jul 1; 368:29-36
Inhaled Insulin vs. Metformin for Type 2 Diabetes
General Medicine Summary and Comment
Inhaled insulin is a new option for type 2 diabetic patients with poor glycemic control on oral monotherapy.
By Allan S. Brett, MD
July 25, 2006
Covering:
Barnett AH et al., Diabetes Care 2006 Jun; 29:1282-7
Drink Coffee, Prevent Diabetes?
Women's Health Summary and Comment
Decaffeinated coffee consumption was associated with reduced incidence of diabetes in women.
By Marian C. Limacher, MD
July 20, 2006
Covering:
Pereira MA et al., Arch Intern Med 2006 Jun 26; 166:1311-6
Inflammatory Cytokines and the Metabolic Syndrome: Animal Clues
Psychiatry Summary and Comment
New directions for studying a syndrome of relevance to psychiatric patients
By Steven Dubovsky, MD
July 17, 2006
Covering:
Netea MG et al., Nat Med 2006 Jul; 12:650-6
Diabetic Nerve Vulnerability to Ischemia
Neurology Summary and Comment
Diabetic nerve appears to be vulnerable to a much shorter period of ischemia than nondiabetic nerve.
By Bruce Taylor, MD
June 8, 2006
Covering:
Baba M et al., Muscle Nerve 2006 Mar; 33:350-5
Retinol-Binding Protein: A Molecule That Predicts Insulin Resistance and Type 2 Diabetes
General Medicine Summary and Comment
Free
RBP4 level was a better predictor than were levels of adipokines, cytokines, or markers of inflammation.
By Anthony L. Komaroff, MD
June 30, 2006
Covering:
Graham TE et al., N Engl J Med 2006 Jun 15; 354:2552-63
Aggressive Lipid Lowering Is Especially Helpful in Diabetics
General Medicine Summary and Comment
Free
For secondary prevention, absolute risk was reduced significantly more in diabetic patients than in nondiabetic patients.
By Keith I. Marton, MD
June 16, 2006
Covering:
Costa J et al., BMJ 2006 May 13; 332:1115-8
Reckless JPD., BMJ 2006 May 13; 332:1103-4
Exercise Benefits Young Patients with Type 1 Diabetes
General Medicine Summary and Comment
Regular physical activity improves glycemic control in children and adolescents with type 1 diabetes without raising their risk for severe hypoglycemia.
By Robert A. Dershewitz, MD, MSc
June 27, 2006
Covering:
Herbst A et al., Arch Pediatr Adolesc Med 2006 Jun; 160:573-7
Smoking and Development of Diabetes
General Medicine Summary and Comment
Even second-hand smoke is associated with development of glucose intolerance.
By Keith I. Marton, MD
June 16, 2006
Covering:
Houston TK et al., BMJ 2006 May 6; 332:1064-7
Risk Factors for Plantar Ulcers in Patients with Diabetes
Dermatology Summary and Comment
Insulin use and poor vision are among the factors that predict which patients with type 2 diabetes will develop foot ulcers.
By Lowell A. Goldsmith, MD, MPH
June 27, 2006
Covering:
Boyko EJ et al., Diabetes Care 2006 Jun; 29:1202-7
