Elevated Glucose Levels and Risk for Incident Heart Failure
Cardiology Summary and Comment
Researchers assessed this association in a large study of patients at high risk for CVD, including those without diabetes.
By Frederick A. Masoudi, MD, MSPH
April 4, 2007
Covering:
Held C et al. for the ONTARGET/TRANSCEND Investigators., Circulation 2007 Mar 20; 115:1371-5
Petrie MC and McMurray JJV., Circulation 2007 Mar 20; 115:1334-5
Antipsychotic-Induced Obesity: Histamine May Be the Key
Psychiatry Summary and Comment
Results from an animal study
By Jonathan Silver, MD
April 2, 2007
Covering:
Kim SF et al., Proc Natl Acad Sci U S A 2007 Feb 27; 104:3456-9
Meltzer HY., Proc Natl Acad Sci U S A 2007 Feb 27; 104:3019-20
Changes in Lung Function with Inhaled Insulin
General Medicine Summary and Comment
Free
A small initial decline in function did not appear to progress beyond 3 months.
By Allan S. Brett, MD
March 29, 2007
Covering:
Skyler JS et al., Diabetes Care 2007 Mar; 30:579-85
Increase in Diabetes in Ontario Far Exceeds Recent Predictions
General Medicine Summary and Comment
The increase, which already surpasses projections for 2030, is largest among young people.
By Bruce Soloway, MD
March 20, 2007
Covering:
Lipscombe LL and Hux JE., Lancet 2007 Mar 3; 369:750-6
Tight Glycemic Control During Cardiac Surgery: No Benefit
General Medicine Summary and Comment
Despite lower glucose concentrations immediately after surgery, patients with tight intraoperative control had no better postoperative outcomes.
By Richard Saitz, MD, MPH, FACP, FASAM
March 15, 2007
Covering:
Gandhi GY et al., Ann Intern Med 2007 Feb 20; 146:233-43
Van den Berghe G., Ann Intern Med 2007 Feb 20; 146:307-8
Progression from Impaired Fasting Glucose to Diabetes
General Medicine Summary and Comment
Progression occurs more slowly in patients at the low end of the new, wider range for IFG.
By Allan S. Brett, MD
March 1, 2007
Covering:
Nichols GA et al., Diabetes Care 2007 Feb; 30:228-33
MRI for the Diagnosis of Foot Osteomyelitis
General Medicine Summary and Comment
In a meta-analysis, magnetic resonance imaging outperformed other imaging methods.
By Jamaluddin Moloo, MD, MPH
February 27, 2007
Covering:
Kapoor A et al., Arch Intern Med 2007 Jan 22; 167:125-32
The Nervous System Might Influence the Risk for Diabetes: An Animal Study
Psychiatry Summary and Comment
The nervous system and the body work together to cause diabetes.
By Steven Dubovsky, MD
February 26, 2007
Covering:
Razavi R et al., Cell 2006 Dec 15; 127:1123-35
Using Lifestyle or Drug Interventions to Prevent or Delay Progression to Type 2 Diabetes
General Medicine Summary and Comment
Free
In a meta-analysis, researchers found that three interventions provided benefit.
By Keith I. Marton, MD
February 20, 2007
Covering:
Gillies CL et al., BMJ 2007 Feb 10; 334:299
Diabetic Ketoacidosis Protocol — Is It Beneficial?
Emergency Medicine Summary and Comment
Implementing a comprehensive mandatory protocol reduced hospital and ICU stay and increased the rate of ED discharge to home.
By Tiffany M. Osborn, MD
February 16, 2007
Covering:
Bull SV et al., Crit Care Med 2007 Jan; 35:41-6
Diabetes Risk with Antihypertensive Meds
Cardiology Summary and Comment
Free
A meta-analysis yields a ranking of antihypertensive drug classes according to their association with incident diabetes.
By Harlan M. Krumholz, MD, SM
February 7, 2007
Covering:
Elliott WJ and Meyer PM., Lancet 2007 Jan 20; 369:201-7
Duloxetine for Diabetic Peripheral Neuropathic Pain
Neurology Summary and Comment
Additional evidence supports the efficacy and safety of duloxetine in patients with DPNP.
By Mohamed A. Elkersh, MD, and Zahid H. Bajwa, MD
February 6, 2007
Covering:
Wernicke JF et al., Neurology 2006 Oct 24; 67:1411-20
Metformin May Influence Weight Gain from Atypicals
Psychiatry Summary and Comment
In a small study of 38 children, metformin seemed safe and effective.
By Barbara Geller, MD
January 12, 2007
Covering:
Klein DJ et al., Am J Psychiatry 2006 Dec; 163:2072-9
Metformin-Induced Vitamin B12 Deficiency
Neurology Summary and Comment
Remember to consider causes of neuropathy in diabetics other than "diabetic neuropathy."
By Laurence J. Kinsella, MD
January 9, 2007
Covering:
Ting RZ et al., Arch Intern Med 2006 Oct 9; 166:1975-9
Let’s Have Another Cup of Coffee
Women's Health Summary and Comment
Caffeine and diabetes: The protection debate continues.
By Diane E. Judge, APN/CNP
January 4, 2007
Covering:
Smith B et al., Diabetes Care 2006 Nov; 29:2385-90
Sitagliptin — A New Oral Agent for Diabetes
General Medicine Summary and Comment
In two studies, patients with type 2 diabetes benefited from this enzyme inhibitor.
By Allan S. Brett, MD
January 2, 2007
Covering:
Aschner P et al., Diabetes Care 2006 Dec; 29:2632-7
Charbonnel B et al., Diabetes Care 2006 Dec; 29:2638-43
Cannabinoid-Receptor–Blocker Appears to Reduce Weight and Lower HbA1c in Diabetics
General Medicine Summary and Comment
Free
With rimonabant, patients reduced weight and cardiovascular risk factors.
By Bruce Soloway, MD
December 19, 2006
Covering:
Scheen AJ et al., Lancet 2006 Nov 11; 368:1660-72
Pioglitazone for Nonalcoholic Steatohepatitis
General Medicine Summary and Comment
In a small study, pioglitazone was associated with several positive histologic and metabolic outcomes.
By Allan S. Brett, MD
December 13, 2006
Covering:
Belfort R et al., N Engl J Med 2006 Nov 30; 355:2297-307
Heart Transplantation in Diabetes Patients
Cardiology Summary and Comment
An analysis of outcomes data from the United Network of Organ Sharing
By Frederick A. Masoudi, MD, MSPH
December 13, 2006
Covering:
Russo MJ et al., Circulation 2006 Nov 21; 114:2280-7
Miller L., Circulation 2006 Nov 21; 114:2206-7
Even After It Ends, a Lifestyle Intervention Prevents Diabetes
General Medicine Summary and Comment
Three years post-intervention, diabetes incidence remained lower among intervention recipients.
By Bruce Soloway, MD
December 12, 2006
Covering:
Lindström J et al., Lancet 2006 Nov 11; 368:1673-9
General Medicine Summary and Comment
This antioxidant supplement (which is unregulated in the U.S.) reduced pain scores.
By Allan S. Brett, MD
December 12, 2006
Covering:
Ziegler D et al., Diabetes Care 2006 Nov; 29:2365-70
Obesity and Diabetes Are Risk Factors for Hepatocellular Carcinoma
Gastroenterology Summary and Comment
Both overweight status and DM were associated independently with HCC in patients with cirrhosis.
By Atif Zaman, MD, MPH
December 8, 2006
Covering:
N’Kontchou G et al., Clin Gastroenterol Hepatol 2006 Aug; 4:1062-8
Screening for Diabetes in Pediatric Primary Care
A chart review in one clinic found that fewer than half of children meeting the ADA criteria for diabetes screening were actually screened.
By Howard Bauchner, MD
December 6, 2006
Covering:
Anand SG et al., Pediatrics 2006 Nov; 118:1888-95
Which Drug for Initial Treatment of Type 2 Diabetes?
General Medicine Summary and Comment
Free
Rosiglitazone was moderately more effective than metformin or glyburide, but costs and adverse events must also be considered.
By Allan S. Brett, MD
December 5, 2006
Covering:
Kahn SE et al., N Engl J Med 2006 Dec 7; 355:2427-43
Nathan DM., N Engl J Med 2006 Dec 7; 355:2477-80
Pioglitazone vs. Glimepiride in Type 2 Diabetes
Cardiology Summary and Comment
Effects on progression of carotid intima-media thickness were compared in a randomized trial.
By Joel M. Gore, MD
December 5, 2006
Covering:
Mazzone T et al., JAMA 2006 Dec 6; 296:2572-81
