Can Exercise Prevent Gestational Diabetes?
Women's Health Summary and Comment
Trial results do not provide a clear answer.
Diabetes Risk Increased with Atypical Antipsychotics in Children
Psychiatry Summary and Comment
Free
Children who take these drugs or antidepressants require rigorous monitoring for diabetes, especially during the first 6 months of therapy.
By Barbara Geller, MD
January 9, 2012
Covering:
Andrade SE et al., Pediatrics 2011 Dec; 128:1135
Long-Term Follow-Up from a Landmark Diabetes Trial
General Medicine Summary and Comment
Free
A period of intensive glycemic control slowed the progression of renal impairment.
By Allan S. Brett, MD
January 5, 2012
Covering:
The DCCT/EDIC Research Group., N Engl J Med 2011 Dec 22; 365:2366
Revised Guidelines: Secondary Prevention and Risk Reduction in Patients with Atherosclerotic Disease
Cardiology Clinical Practice Guideline Watch
Free
New recommendations for cardiac rehabilitation and risk reduction are welcome, but updated guidance is lacking on lipid and blood pressure management.
By JoAnne M. Foody, MD
January 4, 2012
Covering:
Smith SC Jr et al., Circulation 2011 Nov 29; 124:2458
Are Diabetes Mellitus and Epilepsy Linked in Children?
Children with type 1 diabetes mellitus have much higher risk for epilepsy than children in the general population.
Treatment Response to Etanercept in Juvenile Idiopathic Arthritis
One third of patients had good responses, and one third had poor responses. Younger age was associated with good response, and female sex and systemic disease were associated with poor response.
Glycemic Control No Worse in Diabetic Patients Who Also Have Psychiatric Illness
Psychiatry Summary and Comment
Over 5 years, diabetics with or without serious mental illness had elevated glycosylated hemoglobin levels.
By Joel Yager, MD
December 5, 2011
Covering:
Brown CH et al., J Nerv Ment Dis 2011 Nov; 199:899
Patients with Diabetes and Prior Stroke Benefit from Thrombolytic Therapy for Treatment of Acute Stroke
Emergency Medicine Summary and Comment
Free
This finding will expand eligibility for thrombolysis in the U.S.
Individual vs. Group Interventions in Patients with Diabetes
General Medicine Summary and Comment
Individual interventions were more effective, but benefits were small.
By Thomas L. Schwenk, MD
October 27, 2011
Covering:
Weinger K et al., Arch Intern Med 2011 Oct 10
Sperl-Hillen J et al., Arch Intern Med 2011 Oct 10
Is Idiopathic Central Diabetes Insipidus Really Idiopathic?
An underlying etiology was later identified in nearly 40% of children initially diagnosed with idiopathic diabetes insipidus.
Briefly Noted
Associations of neurologic disorders with bullous pemphigoid and of disrupted glucose metabolism with porphyria cutanea tarda
Venous Blood Gas Electrolyte Levels Accurate for Diagnosis of DKA
Emergency Medicine Summary and Comment
Findings suggest that VBG electrolyte results can be used in lieu of serum chemistry panel results to diagnose diabetic ketoacidosis.
No Association Found Between Urinary BPA and Type 2 Diabetes
General Medicine Summary and Comment
New study calms some concerns about bisphenol A, widely used in plastic and metal containers for food and drink.
α-Lipoic Acid Is Ineffective for Diabetic Neuropathy
General Medicine Summary and Comment
Objective improvement was borderline, and symptom relief was nil.
By Allan S. Brett, MD
October 13, 2011
Covering:
Ziegler D et al., Diabetes Care 2011 Sep; 34:2054
Time Trends for Mortality Among Patients with Early- vs. Late-Onset Type 1 Diabetes
General Medicine Summary and Comment
Early-onset patients are faring better, but late-onset patients are doing worse.
Each Lifestyle Factor Adds to Diabetes Risk
General Medicine Summary and Comment
Unsurprisingly, the strongest predictor was elevated body-mass index.
Perioperative Glycemic Control in Patients Undergoing CABG
General Medicine Summary and Comment
Among patients undergoing coronary artery bypass grafting, a target glucose level of 120–180 mg/dL was as good as 90–120 mg/dL, with less hypoglycemia.
By Allan S. Brett, MD
September 29, 2011
Covering:
Lazar HL et al., Ann Surg 2011 Sep; 254:458
Glucose Variability Affects Hemoglobin A1c
General Medicine Summary and Comment
At any given average glucose level, high variability results in higher glycosylated hemoglobin level.
By Allan S. Brett, MD
September 13, 2011
Covering:
Kuenen JC et al., Diabetes Care 2011 Aug; 34:1843
Intensive Glucose-Lowering Treatment Does Not Lower 5-Year Mortality
General Medicine Summary and Comment
In this meta-analysis, treatment did not lower risks for other adverse outcomes associated with type 2 diabetes.
Hemoglobin A1c Level vs. Diagnosis of Diabetes as a Predictor of Cardiovascular Risk
General Medicine Summary and Comment
Adding glycosylated hemoglobin measurement improved ability to predict cardiovascular risk, but the clinical implications are unclear.
A Potentially Treatable Form of Diabetic Neuropathy
Neurology Summary and Comment
Careful phenotyping identifies a painless diabetic motor neuropathy — a variant of diabetic lumbosacral radiculoplexus neuropathy (diabetic amyotrophy) — that may respond to immunotherapy.
A SNP for the Increased Risk for Diabetes in Schizophrenia
Psychiatry Summary and Comment
An allele that is frequently associated with diabetes risk is found to have elevated prevalence in schizophrenia patients.
By Steven Dubovsky, MD
July 25, 2011
Covering:
Hansen T et al., Biol Psychiatry 2011 Jul 1; 70:59
Risk for Diabetes Increases with Statin Dose
General Medicine Summary and Comment
Risk was highest with intensive-dose therapy.
Patients Taking Disease-Modifying Antirheumatic Drugs Also Developed Less New Diabetes
Dermatology Summary and Comment
Free
Decreased incidence was associated with TNF antagonists and hydroxychloroquine but not with methotrexate.
By Jeffrey P. Callen, MD
July 15, 2011
Covering:
Solomon DH et al., JAMA 2011 Jun 22/29; 305:2525
Bongartz T and Kudva Y., JAMA 2011 Jun 22/29; 305:2573
Pass on HbA1c for Detecting Diabetes in Adolescents
HbA1c did not perform as well as traditional measures for diagnosing diabetes mellitus in high-risk adolescents.
