Emerging Perspectives: Psychopathology and the Serotonin Transporter
Psychiatry
Summary and Comment
The effect of the short-allele variant on depression may be secondary to more general effects.
By Steven Dubovsky, MD
April 30, 2007
Covering:
Covault J et al., Biol Psychiatry 2007 Mar 1; 61:609-16
Kraft JB et al., Biol Psychiatry 2007 Mar 15; 61:734-42
Young KA et al., Biol Psychiatry 2007 Mar 15; 61:813-8
Cross-Cultural Features of Social Anxiety Diagnoses
Psychiatry
Summary and Comment
American clinicians might need to assess patients fears of offending others.
By Deborah Cowley, MD
April 30, 2007
Covering:
Choy Y et al., Depress Anxiety 2007 Mar 5
Does Mental Torture Hurt Less than Physical Torture?
Psychiatry
Summary and Comment
Distress and helplessness have greater psychological consequences than does the type of torture.
By Steven Dubovsky, MD
April 30, 2007
Covering:
Ba o lu M et al., Arch Gen Psychiatry 2007 Mar; 64:277-85
Miles SH., Arch Gen Psychiatry 2007 Mar; 64:275-6
Antidepressants During Pregnancy: Treating the Condition While Acknowledging the Risks
Decisions about treating depression during pregnancy must be individualized.
By Claudio N. Soares, MD, PhD
April 26, 2007
Making Informed Decisions About Antidepressants During Pregnancy
Women's Health
Patient Information
Benefits, risks, and individual needs play guiding roles in decisions about antidepressant use.
By Diane E. Judge, APN/CNP
April 26, 2007
Good Mothering, Good Mood For Some
Psychiatry
Summary and Comment
Nurturance during childhood may protect against depression in adults with certain serotonin-receptor polymorphisms.
By Barbara Geller, MD
April 23, 2007
Covering:
Jokela M et al., Arch Gen Psychiatry 2007 Mar; 64:356-60
Antidepressants in Pediatric Patients: Benefits Might Outweigh Risks
Psychiatry
Summary and Comment
Free
SSRIs still have their uses, despite suicidality risks and less prescribing for children.
By Peter Roy-Byrne, MD
April 17, 2007
Covering:
Bridge JA et al., JAMA 2007 Apr 18; 297:1683-96
Nemeroff CB et al., Arch Gen Psychiatry 2007 Apr; 64:466-72
Delirium After Hematopoietic Stem-Cell Transplantation Affects HRQOL
Oncology and Hematology
Summary and Comment
Free
In a stem-cell transplant population, delirium was associated with adverse effects on neurocognition and with high levels of distress at 80 days post-transplant.
By Barbara A. Murphy, MD
April 13, 2007
Covering:
Fann JR et al., J Clin Oncol 2007 Apr 1; 25:1223-31
Hostile Waters: Why CBT Sometimes Does Not Work for Patients with GAD
Psychiatry
Summary and Comment
Free
Level and type of criticism by relationship partners predicted efficacy.
By M. Katherine Shear, MD
April 9, 2007
Covering:
Zinbarg RE et al., Behav Res Ther 2007 Apr; 45:699-713
Hoarding Might Run in the Family
Psychiatry
Summary and Comment
The genetic evidence begins to accumulate.
By Joel Yager, MD
April 9, 2007
Covering:
Samuels J et al., Am J Psychiatry 2007 Mar; 164:493-9
Saxena S., Am J Psychiatry 2007 Mar; 164:380-4
Suicide and the Nightmarish Life
Neurology
Summary and Comment
This study reveals that nightmares are associated with suicidality and that sleep dysfunction is prevalent among people who attempt suicide.
By Gregory Fricchione, MD
April 3, 2007
Covering:
Sjöström N et al., Sleep 2007 Jan 1; 30:91-5
Deep Brain Stimulation for Tardive Dyskinesia
Psychiatry
Summary and Comment
A pilot study shows highly promising results.
By Steven Dubovsky, MD
April 2, 2007
Covering:
Damier P et al., Arch Gen Psychiatry 2007 Feb; 64:170-6
Antipsychotic-Induced Obesity: Histamine May Be the Key
Psychiatry
Summary and Comment
Results from an animal study
By Jonathan Silver, MD
April 2, 2007
Covering:
Kim SF et al., Proc Natl Acad Sci U S A 2007 Feb 27; 104:3456-9
Meltzer HY., Proc Natl Acad Sci U S A 2007 Feb 27; 104:3019-20
Are Add-On Antidepressants Ineffective for Bipolar Depression?
Psychiatry
Summary and Comment
Free
Antidepressants and placebo showed similar results when given adjunctively with mood stabilizers.
By Peter Roy-Byrne, MD
March 28, 2007
Covering:
Sachs GS et al., N Engl J Med 2007 Mar 28
Is Depression an Independent Risk Factor for Stroke?
Neurology
Summary and Comment
Depressive symptoms are associated with increased risk for stroke or TIA but only in people younger than 65.
By Rima M. Dafer, MD, MPH, FAHA, and José Biller, MD, FACP, FAAN, FAHA
March 27, 2007
Covering:
Salaycik KJ et al., Stroke 2007 Jan; 38:16-21
Carod-Artal FJ., Stroke 2007 Jan; 38:1-3
Is the Stage Theory of Grief Empirically Valid?
Psychiatry
Summary and Comment
Free
This attempt at confirming the popular theory falls short.
By Peter Roy-Byrne, MD, and M. Katherine Shear, MD
March 26, 2007
Covering:
Maciejewski PK et al., JAMA 2007 Feb 21; 297:716-23
An Endophenotype in OCD Is Familial
Psychiatry
Summary and Comment
Unaffected relatives of OCD patients have cognitive inflexibility and motor impulsivity.
By Joel Yager, MD
March 26, 2007
Covering:
Chamberlain SR et al., Am J Psychiatry 2007 Feb; 164:335-8
Is General Headache Associated with Depression?
Emergency Medicine
Summary and Comment
More than one quarter of patients with headache of any type often had moderate or severe depression.
By Richard D. Zane, MD, FAAEM
March 23, 2007
Covering:
Jelinski SE et al., Neurology 2007 Feb 13; 68:489-95
Anxiety Disorders Are Common and Undertreated in Primary Care
General Medicine
Summary and Comment
Anxiety is as common as depression but receives less attention.
By Richard Saitz, MD, MPH, FACP, FASAM
March 20, 2007
Covering:
Kroenke K et al., Ann Intern Med 2007 Mar 6; 146:317-25
Katon W and Roy-Byrne P., Ann Intern Med 2007 Mar 6; 146:390-2
Do Chronic Headache, Low Education, and Somatic Symptoms Predict Depression?
Neurology
Summary and Comment
Depression and somatic symptoms are more likely to coexist in patients with chronic versus episodic headache, suggesting that these symptoms may have a common underlying neurochemical etiology.
By Autumn Klein, MD, PhD
March 20, 2007
Covering:
Tietjen GE et al., Neurology 2007 Jan 9; 68:134-40
Venlafaxine for Generalized Anxiety Disorder in Children?
Psychiatry
Summary and Comment
Findings from two related studies include lack of efficacy in one study and possible adverse cardiovascular, growth, and lipid effects.
By Barbara Geller, MD
March 19, 2007
Covering:
Rynn MA et al., Am J Psychiatry 2007 Feb; 164:290-300
Psychiatric Disorders Are Prevalent in Patients Seeking Bariatric Surgery
Psychiatry
Summary and Comment
More-obese bariatric-surgery candidates have higher rates of psychiatric illness.
By Joel Yager, MD
March 19, 2007
Covering:
Kalarchian MA et al., Am J Psychiatry 2007 Feb; 164:328-34
The Effect of Oral Contraceptives on Depressive Symptoms
Women's Health
Summary and Comment
Culprit or cure? The jurys still out.
By Claudio N. Soares, MD, PhD
March 15, 2007
Covering:
Duke JM et al., Contraception 2007 Jan; 75:27-31
Depression Associated with Death and Hospitalization in Patients with Heart Failure
General Medicine
Summary and Comment
Unexpectedly, so was antidepressant use.
By Jamaluddin Moloo, MD, MPH
March 13, 2007
Covering:
Sherwood A et al., Arch Intern Med 2007 Feb 26; 167:367-73
Psychodynamic Psychotherapy for Panic Disorder?
Psychiatry
Summary and Comment
Free
A randomized controlled trial yields positive results.
By Joel Yager, MD
March 12, 2007
Covering:
Milrod B et al., Am J Psychiatry 2007 Feb; 164:265-72