Cognitive-Behavioral Therapy in Patients with Coronary Artery Disease
General Medicine
Summary and Comment
CBT focused on alleviating stress and hostility and was associated with significantly fewer second events.
By Thomas L. Schwenk, MD
February 8, 2011
Covering:
Gulliksson M et al., Arch Intern Med 2011 Jan 24; 171:134
Are You SERTain of That?
Psychiatry
Summary and Comment
Free
Another view, via a novel meta-analytic technique, of the serotonin-transporter gene–environment interaction
By Steven Dubovsky, MD
February 7, 2011
Covering:
Karg K et al., Arch Gen Psychiatry 2011 Jan 3
Effects of Personality Disorder on Recovery from Depression
Psychiatry
Summary and Comment
Comorbid personality disorder predicts slower remission and more rapid relapse in major depression.
By Peter Roy-Byrne, MD
February 7, 2011
Covering:
Grilo CM et al., J Clin Psychiatry 2010 Dec; 71:1629
Has the Association Between Abortion and Mental Illness Been Overstated?
Women's Health
Summary and Comment
A large Danish study showed no link between first-trimester abortion and subsequent mental health problems.
Long-Term PTSD Symptoms Among 9/11 Survivors
Psychiatry
Summary and Comment
Among other factors, having low earnings put 9/11 survivors at greater risk for post-traumatic stress disorder.
By Joel Yager, MD
January 31, 2011
Covering:
DiGrande L et al., Am J Epidemiol 2011 Feb 1; 173:271
Depression and Diabetes — A Bad Combination
Psychiatry
Summary and Comment
In the Nurses' Health Study, both conditions increased all-cause and cardiovascular mortality, and the combination was worse than either condition alone.
By Steven Dubovsky, MD
January 31, 2011
Covering:
Pan A et al., Arch Gen Psychiatry 2011 Jan; 68:42
Polycystic Ovary Syndrome as a Risk Factor for Depression
Women's Health
Summary and Comment
Psychological distress should be considered in all women with PCOS.
By Robert W. Rebar, MD
January 27, 2011
Covering:
Dokras AS et al., Obstet Gynecol 2011 Jan; 117:145
Reviews of Note
Irritability in children; molecular depression; choosing depression treatments; good-quality psychotherapy studies; psychedelic drugs in psychiatric research; borderline personality disorder; genomic imprinting; 1000 genomes; methylation and behavior; the hippocampus in schizophrenia; antipsychotics and reasoning biases; and monitoring lithium
Preventive Effects of Mindfulness in Recurrent Depression
Psychiatry
Summary and Comment
Free
A potentially valuable approach, especially for patients with unstable remissions who wish to discontinue their medication after successful acute treatment.
By Peter Roy-Byrne, MD
January 14, 2011
Covering:
Segal ZV et al., Arch Gen Psychiatry 2010 Dec; 67:1256
How Suicidal Are Psychotic Patients?
Psychiatry
Summary and Comment
The risk seems lower than previously reported, but it remains elevated for more than 10 years after the patient's first presentation.
By Steven Dubovsky, MD
January 14, 2011
Covering:
Dutta R et al., Arch Gen Psychiatry 2010 Dec; 67:1230
Coordinated Care of Depression and Chronic Physical Illness
General Medicine
Summary and Comment
Significant improvements were realized in risk factor control, quality of life, and satisfaction with care.
Unique Cardiovascular Risks of Tricyclic Antidepressants
Psychiatry
Summary and Comment
An epidemiologic study shows that use of this class of drugs increases the risk for cardiovascular disease.
Exploring a New Pathway for Treating Anxiety and Mood Disorders
Psychiatry
Summary and Comment
An animal study finds that a small-molecule agonist of the TrkB receptor alters fear extinction.
By Joel Yager, MD
January 10, 2011
Covering:
Andero R et al., Am J Psychiatry 2010 Dec 1
Thinking About Thinking as a Therapeutic Approach
Psychiatry
Year in Review
Metacognitive therapy shows promise across a range of psychiatric conditions.
Will We Have Rapid-Onset Antidepressants? How Might They Work?
Psychiatry
Year in Review
Selective antagonists of the <$EMPH_O>N<$EMPH_C>-methyl-D-aspartate receptor may quickly ease depressive symptoms — but much work remains before they become clinically useful.
PTSD, Fear Processing, and the Future of Treatment
Psychiatry
Year in Review
With a clearer understanding of the neurobiological mechanisms and subtypes of post-traumatic stress disorder, we can devise effective treatments.
The Infancy of Prenatal and Infant Psychiatry
Psychiatry
Year in Review
Multiple animal and human studies are focusing on early maternal behaviors and biological causes of the development of psychiatric illness.
Psychiatry — Is It Brain Surgery?
Psychiatry
Year in Review
No, or at least, not yet
Vitamin of the Year?
Psychiatry
Year in Review
Let the sunshine in: Vitamin D deficiency has neuropsychiatric implications.
Does Vascular Depression Exist?
Psychiatry
Summary and Comment
Free
A prospective study suggests that atherosclerosis does not contribute to depression but leaves open other possible associations between vascular disorders and late-onset depression.
By Steven Dubovsky, MD
December 13, 2010
Covering:
Newson RS et al., Arch Gen Psychiatry 2010 Nov; 67:1144
Suicide Risk After Bariatric Surgery?
Psychiatry
Summary and Comment
The long-term risk seems to increase, but psychiatric comorbidities and surgical sequelae may also be factors.
By Joel Yager, MD
December 13, 2010
Covering:
Tindle HA et al., Am J Med 2010 Nov; 123:1036
The p11 Protein and Depression
Psychiatry
Summary and Comment
Could gene-transfer therapy eventually be a treatment for depression?
By Barbara Geller, MD
December 6, 2010
Covering:
Alexander B et al., Sci Transl Med 2010 Oct 20; 2:54ra76
Suicide Attempts in the Population: What Counts?
Psychiatry
Summary and Comment
The largest proportion of suicide attempts is attributed to four specific psychiatric disorders.
By Joel Yager, MD
December 6, 2010
Covering:
Bolton JM and Robinson J., Am J Public Health 2010 Dec; 100:2473
Olanzapine for Hair Pulling
Psychiatry
Summary and Comment
While effective in this small study, the drug has metabolic adverse effects.
By Peter Roy-Byrne, MD
December 6, 2010
Covering:
Van Ameringen M et al., J Clin Psychiatry 2010 Oct; 71:1336
Isotretinoin, Severe Acne, and Suicide: A Complicated Story
Psychiatry
Summary and Comment
Free
Severe acne may increase risk for suicide, and isotretinoin might exacerbate the risk.
By Peter Roy-Byrne, MD
November 22, 2010
Covering:
Sundström A et al., BMJ 2010 Nov 11; 341:c5812