Common Mental Disorder Elevates Risk for Subsequent Obesity
General Medicine Summary and Comment
However, obesity is not associated with elevated risk for later mental disorder.
Subjectively Poor Sleep Correlates with Postpartum Depression
Neurology Summary and Comment
In a questionnaire study, this association held true even after adjustments for other known risk factors for depression.
By Brian J. Murray MD, FRCPC D, ABSM
November 3, 2009
Covering:
Dørheim SK et al., Sleep 2009 Jul; 32:847
Deep Brain Stimulation: Slow Speed Ahead
Psychiatry Summary and Comment
More needs to be learned about patient selection, electrode placement, and outcomes before routine clinical adoption of DBS for depression or OCD.
By Steven Dubovsky, MD
November 2, 2009
Covering:
Rabins P et al., Arch Gen Psychiatry 2009 Sep; 66:931
Collaborative Care Improves Guideline Concordance for Bipolar Disorder
Psychiatry Summary and Comment
However, whether it improves outcomes remains unknown.
By Joel Yager, MD
November 2, 2009
Covering:
Bauer MS et al., Am J Psychiatry 2009 Oct 1
Implications of Comorbid Anxiety for Prognosis of Bipolar Disorder
Psychiatry Summary and Comment
Anxiety adds to risks for subsequent depression in bipolar patients.
By Joel Yager, MD
November 2, 2009
Covering:
Coryell W et al., Am J Psychiatry 2009 Oct 1
Varenicline Use and Risk for Self-Harm and Suicide
General Medicine Summary and Comment
Patients who received varenicline, bupropion, or nicotine replacement all had similar risks.
Psychological Health in Central Hypersomnias: The French Harmony Study
Neurology Summary and Comment
An ambitious and impressive study of central hypersomnias — including cataplectic narcolepsy, narcolepsy without cataplexy, and idiopathic hypersomnia — helps to clarify the associations of these entities with each other, with depressive symptomatology, and with treatment response.
By Demetrios A. Julius, MD
October 27, 2009
Covering:
Dauvilliers Y et al., J Neurol Neurosurg Psychiatry 2009 Jun; 80:636
Treating Depressed Cardiac Patients? Omega-3s Don't Help the Depression
Psychiatry Summary and Comment
Omega-3 fatty acids do not appear to augment the effects of sertraline in depressed patients with cardiac disease.
Depression Is Bad for Your Heart
Psychiatry Summary and Comment
And attaining remission significantly improves mortality risk in patients with acute coronary syndromes.
By Steven Dubovsky, MD
October 26, 2009
Covering:
Glassman AH et al., Arch Gen Psychiatry 2009 Sep; 66:1022
Genetic Risk Factors for Post-Traumatic Stress Disorder
Psychiatry Summary and Comment
A genetic study finds strong connections between PTSD and genes that regulate activity in the glucocorticoid receptor.
By Steven Dubovsky, MD
October 26, 2009
Covering:
Yehuda R et al., Biol Psychiatry 2009 Oct 1; 66:708
Prenatal Exposure to SSRIs Can Adversely Affect Certain Delivery Outcomes
Women's Health Summary and Comment
In utero SSRI exposure was associated with excess risk for preterm delivery and related complications but not for lower birth weight or smaller head circumference.
By Wendy S. Biggs, MD
October 22, 2009
Covering:
Lund N et al., Arch Pediatr Adolesc Med 2009 Oct; 163:949
More About SSRI Use During Pregnancy
Psychiatry Summary and Comment
Free
A population-based cohort study reports SSRI-associated cardiac septal defects.
By Deborah Cowley, MD
October 19, 2009
Covering:
Pedersen LH et al., BMJ 2009 Sep 23; 339:b3569
Chambers C., BMJ 2009 Sep 23; 339:b3525
Do Antidepressants Quickly Reverse Negative Affective Biases?
Psychiatry Summary and Comment
Antidepressants may have an immediate psychological effect.
By Joel Yager, MD
October 19, 2009
Covering:
Harmer CJ et al., Am J Psychiatry 2009 Oct; 166:1178
Inflammatory Proteins: The Body–Brain Connection
Psychiatry Summary and Comment
Inflammatory response to vaccination affected participants' sense of well-being and activated specific cortical regions but did not worsen cognitive performance.
By Steven Dubovsky, MD
October 19, 2009
Covering:
Harrison NA et al., Biol Psychiatry 2009 Sep 1; 66:415
Harrison NA et al., Biol Psychiatry 2009 Sep 1; 66:407
Review of Associations Between Sleepiness and Depression
Neurology Summary and Comment
Sleep and depression are so complex that a review article can only describe, not answer, specific questions about their interaction.
By Quentin Regestein, MD
October 13, 2009
Covering:
Chellappa SL et al., Sleep Med 2009 May; 10:505
A Step Toward Personalized Treatment of Depression
Psychiatry Summary and Comment
Further analyses of genome-wide association data generate a multilocus model of antidepressant response.
By Steven Dubovsky, MD
October 9, 2009
Covering:
Ising M et al., Arch Gen Psychiatry 2009 Sep; 66:966
Strep Antibodies and PANDAS: An Animal Study
Psychiatry Summary and Comment
Researchers tie behavioral abnormalities to strep-associated antibodies.
By Barbara Geller, MD
October 9, 2009
Covering:
Yaddanapudi K et al., Mol Psychiatry 2009 Aug 11
Management of Chronic Pain
Comprehensive treatment for chronic pain must address both physical and psychological aspects.
By Lynn Rader, MD
October 8, 2009
Treating Adolescent Depression — A TAD Better
Psychiatry Summary and Comment
A year after the end of the study, TADS-treated adolescents hold their own.
By Joel Yager, MD
October 5, 2009
Covering:
Treatment for Adolescents With Depression Study (TADS) Team., Am J Psychiatry 2009 Oct; 166:1141
Neurocognitive Responses in Psoriasis Patients
Dermatology Summary and Comment
Free
Imaging in patients with psoriasis shows brain changes that blunt responses to expressions of disgust in others.
By Craig A. Elmets, MD
October 2, 2009
Covering:
Kleyn CE et al., J. Invest Dermatol 2009 Aug 27
Are Developing Hearts Harmed by SSRIs?
Women's Health Summary and Comment
First-trimester fetal exposure to SSRIs more than doubled risk for septal heart defects; absolute differences in incidence were small.
By Wendy S. Biggs, MD
October 1, 2009
Covering:
Pedersen LH et al., BMJ 2009 Sep 23; 339:b3569
Chambers C., BMJ 2009 Sep 23; 339:b3525
Joint APA-ACOG Algorithms for Treatment of Depression During Pregnancy
Psychiatry Summary and Comment
Free
A groundbreaking collaboration provides useful advice on a clinically challenging problem.
By Deborah Cowley, MD
September 28, 2009
Covering:
Yonkers KA et al., Gen Hosp Psychiatry 2009 Sep/Oct; 31:403
Online Psychotherapy for Depression
Psychiatry Summary and Comment
Instant messaging of therapy provides surprisingly positive results.
By Peter Roy-Byrne, MD
September 28, 2009
Covering:
Kessler D et al., Lancet 2009 Aug 22; 374:628
Simon GE and Ludman EJ., Lancet 2009 Aug 22; 374:594
Long-Term Relief of Poststroke Depression
Psychiatry Summary and Comment
Brief interventions that educate patients and teach a problem-solving approach might have a long-lived effect.
By Jonathan Silver, MD
September 28, 2009
Covering:
Mitchell PH et al., Stroke 2009 Sep; 40:3073
Psychiatric Morbidities in Gay and Bisexual Subgroups
Psychiatry Summary and Comment
Mood and anxiety disorders were more common in bisexuals and gay men than in heterosexuals.
By Joel Yager, MD
September 28, 2009
Covering:
Bostwick WB et al., Am J Public Health 2009 Aug 20
