Adding Zoledronic Acid to Endocrine Therapy for Premenopausal Breast Cancer
Women's Health Summary and Comment
Free
European trial results suggest that adding IV bisphosphonate therapy improves outcomes.
The Next Adjuvant Therapy for Breast Cancer?
Adding zoledronic acid to endocrine therapy improved disease-free survival in patients with early-stage disease.
Estrogen-Progestin Therapy and Risk for Breast Cancer: More Findings from the WHI
Women's Health Summary and Comment
Free
Postintervention WHI data show risk rose during, and fell after, use of combination HT.
By Andrew M. Kaunitz, MD
February 4, 2009
Covering:
Chlebowski RT et al., N Engl J Med 2009 Feb 5; 360:573
Breast Cancer and Postmenopausal Hormone Therapy
Less HT use parallels recent declines in breast cancer incidence.
Sorafenib for Metastatic Breast Cancer
If it doesn’t make you sick, does that mean it isn’t working? Patients experienced few serious side effects and no objective response.
By William J. Gradishar, MD
February 3, 2009
Covering:
Moreno-Aspitia A et al., J Clin Oncol 2009 Jan 1; 27:11
Bergh J., J Clin Oncol 2009 Jan 1; 27:2
Delaying Radiation Therapy After Breast-Conserving Surgery
Patients who delayed RT for more than 20 weeks had poorer survival outcomes than did those who initiated RT 4 to 8 weeks after BCS.
Mammography Surveillance for Childhood Cancer Survivors
General Medicine Summary and Comment
Free
Only about half received appropriate regular screening mammography.
Routine Clinical vs. Telephone Follow-Up After Treatment for Breast Cancer
General Medicine Summary and Comment
No differences in anxiety levels were reported between groups.
Meeting Report: The 2008 San Antonio Breast Cancer Symposium
A summary of the latest findings in breast cancer research
Adjuvant Bisphosphonate for Early-Stage Breast Cancer
Overall survival benefit of adding oral clodronate to standard adjuvant therapy was maintained after more than 8 years of follow-up.
Why Is Advanced Breast Cancer More Common in Overweight and Obese Women?
Women's Health Summary and Comment
Excess risk was not explained by differences in mammography screening frequency and accuracy.
By Andrew M. Kaunitz, MD
December 30, 2008
Covering:
Kerlikowske K et al., J Natl Cancer Inst 2008 Dec 3; 100:1724
Sentinel Lymph Node Biopsy and Lymphedema
Lymphedema was less common after SLNB than after axillary lymph node dissection.
By William J. Gradishar, MD
December 23, 2008
Covering:
McLaughlin SA et al., J Clin Oncol 2008 Nov 10; 26:5213
McLaughlin SA et al., J Clin Oncol 2008 Nov 10; 26:5220
Do Some Breast Cancers Disappear?
Women's Health Summary and Comment
Free
Provocative Norwegian study results suggest that the answer is yes.
By Andrew M. Kaunitz, MD
December 18, 2008
Covering:
Zahl P-H et al., Arch Intern Med 2008 Nov 24; 168:2311
Kaplan RM and Porzsolt F., Arch Intern Med 2008 Nov 24; 168:2302
Silver Lining for Women with Migraines?
Women's Health Summary and Comment
History of migraine was associated with lower risk for breast cancer.
By Andrew M. Kaunitz, MD
December 18, 2008
Covering:
Mathes RW et al., Cancer Epidemiol Biomarkers Prev 2008 Nov; 17:3116
When Hot Flashes Are Good News
Women's Health Summary and Comment
Menopausal symptoms associated with anti-estrogen therapy predicted lower risk for breast cancer recurrence.
Vitamin B and Cancer Risk in Women
General Medicine Summary and Comment
Once again, no benefits were observed with vitamin supplementation.
Vitamin D and Risk for Breast Cancer According to Hormone-Receptor Status
Women's Health Summary and Comment
Free
Vitamin D protected against breast cancer, regardless of ER/PR status.
By Andrew M. Kaunitz, MD
November 13, 2008
Covering:
Blackmore KM et al., Am J Epidemiol 2008 Oct 15; 168:915
Does Caffeine Consumption Affect Breast Cancer Risk?
Women's Health Summary and Comment
A large cohort study showed no overall association.
By Andrew M. Kaunitz, MD
November 13, 2008
Covering:
Ishitani K et al., Arch Intern Med 2008 Oct 13; 168:2022
Is Hormone Therapy Safe for BRCA -Mutation Carriers?
Risk for breast cancer was lower for postmenopausal carriers who received hormone therapy than for those who did not.
By William J. Gradishar, MD
October 28, 2008
Covering:
Eisen A et al., J Natl Cancer Inst 2008 Oct 1; 100:1361
Chlebowski RT and Prentice RL., J Natl Cancer Inst 2008 Oct 1; 100:1341
Hormone Therapy: Safe for BRCA1 Mutation Carriers?
Women's Health Summary and Comment
Free
Reassuring findings from a case-control study: Surprisingly, protection against breast cancer is a possible outcome.
By Andrew M. Kaunitz, MD
October 23, 2008
Covering:
Eisen A et al., J Natl Cancer Inst 2008 Oct 1; 100:1361
Hypnosis for Hot Flashes in Breast Cancer Survivors?
Women's Health Summary and Comment
As a nonhormonal treatment for vasomotor symptoms, hypnosis warrants more study.
By Andrew M. Kaunitz, MD
October 23, 2008
Covering:
Elkins G et al., J Clin Oncol 2008 Sep 22
Avis NE., J Clin Oncol 2008 Sep 22
Zoledronic Acid for Preventing Bone Loss in Young Breast Cancer Patients
Women's Health Summary and Comment
Intravenous bisphosphonate prevented loss of BMD associated with chemotherapy.
By Andrew M. Kaunitz, MD
October 23, 2008
Covering:
Hershman DL et al., J Clin Oncol 2008 Oct 10; 26:4739
Tracking Tumor Perfusion in Locally Advanced Breast Cancer
Changes in tumor perfusion during neoadjuvant chemotherapy were predictive of survival outcomes.
Is Computer-Aided Detection Good for Screening Mammography?
Women's Health Summary and Comment
Free
CAD seemed to raise mammography recall rate in a U.K. study, but the implications for U.S. practice are unclear.
Is Computer-Aided Detection Good for Screening Mammography?
CAD seemed to raise mammography recall rate in a U.K. study, but the implications for U.S. practice are unclear.
