Brunettes Have Less Fun
Dermatology
Summary and Comment
As more and younger people color their hair, allergic reactions to hair dye are on the rise.
By Mark V. Dahl, MD
March 2, 2007
Covering:
McFadden JP et al., BMJ 2007 Feb 3; 334:220
Children with EoE Respond to Oral Fluticasone Propionate
Gastroenterology
Summary and Comment
FP improved vomiting symptoms and histologic parameters of eosinophilic esophagitis.
By David A. Johnson, MD
March 2, 2007
Covering:
Konikoff MR et al., Gastroenterology 2006 Nov; 131:1381-91
Predicting Response to Inhaled Steroids in Asthma
General Medicine
Summary and Comment
Response at 6 weeks predicted longer-term response in people with persistent asthma.
By Allan S. Brett, MD
February 1, 2007
Covering:
Martin RJ et al., J Allergy Clin Immunol 2007 Jan; 119:73-80
Dietary Treatment of Eosinophilic Esophagitis in Children
Gastroenterology
Summary and Comment
In children with EoE, elimination diets might be the preferred treatment.
By David A. Johnson, MD
January 5, 2007
Covering:
Kagalwalla AF et al., Clin Gastroenterol Hepatol 2006 Sep; 4:1097-102
Long-Acting Inhaled ß-Agonists and Mortality
Earlier in 2006, findings highlighted increased risk for asthma-related deaths; more recently, experts have suggested the risks were due to use of these medications without inhaled steroids.
By Richard Saitz, MD, MPH, FACP, FASAM
December 28, 2006
Does Home Use of Peak Flow Meters Improve Asthma Management in Adults?
General Medicine
Summary and Comment
Peak flow monitoring did not improve outcomes in patients who were middle-aged and older.
By Allan S. Brett, MD
December 12, 2006
Covering:
Buist AS et al., Am J Respir Crit Care Med 2006 Nov 15; 174:1077-87
Can We Prevent Anaphylactic Reactions to Contrast Media?
General Medicine
Summary and Comment
Free
Given how infrequent severe reactions are, pretreatment does not seem worthwhile.
By Keith I. Marton, MD
November 16, 2006
Covering:
Tramèr MR et al., BMJ 2006 Sep 30; 333:675-8
Dawson P., BMJ 2006 Sep 30; 333:663-4
Respiratory Benefits of a Legislative Ban on Smoking in Public Places
General Medicine
Summary and Comment
A Scottish study shows that the benefits extend to inflammatory markers and pulmonary function.
By Thomas L. Schwenk, MD
November 7, 2006
Covering:
Menzies D et al., JAMA 2006 Oct 11; 296:1742-8
Eisner MD., JAMA 2006 Oct 11; 296:1778-9
Preventive Care for Children with Asthma
General Medicine
Summary and Comment
Prompting clinicians led to higher rates of preventive care delivery but left considerable room for improvement.
By Robert Dershewitz, MD, MSc
November 2, 2006
Covering:
Halterman JS et al., Arch Pediatr Adolesc Med 2006 Oct; 160:1018-25
Inhaled Corticosteroids and Risk for Fracture
General Medicine
Summary and Comment
In an observational study, high-dose inhaled steroids were associated with increased fracture risk among elders.
By Allan S. Brett, MD
October 25, 2006
Covering:
Hubbard R et al., Chest 2006 Oct; 130:1082-8
Sunscreens: How Safe Are They?
Dermatology
Summary and Comment
For some people, sunscreens can cause allergic and photoallergic reactions.
By Craig A. Elmets, MD
October 20, 2006
Covering:
Bryden AM et al., Br J Dermatol 2006 Oct; 155:737-47
Rescue Therapy and Secondary Prevention of Asthma
Inhaled budesonide-formoterol was better than formoterol alone for rescue therapy, and early use of inhaled fluticasone did not prevent later development of asthma.
By F. Bruder Stapleton, MD
October 4, 2006
Covering:
Rabe KF et al., Lancet 2006 Aug 26; 368:744-53
Murray CS et al., Lancet 2006 Aug 26; 368:754-62
Atopy Predicts Asthma in Young Children Who Wheeze
General Medicine
Summary and Comment
Early atopic sensitization and allergen exposure was a marker for development of chronic airway disease, but inhaled corticosteroids did not prevent progression from atopy to asthma.
By Bruce Soloway, MD
October 3, 2006
Covering:
Murray CS et al., Lancet 2006 Aug 26; 368:754-62
Illi S et al., Lancet 2006 Aug 26; 368:763-70
Inhaled vs. Oral Steroids for Children with Mild-to-Moderate Acute Asthma
Oral steroids outperformed inhaled corticosteroids for mild-to-moderate acute asthma.
By Howard Bauchner, MD
September 13, 2006
Covering:
Schuh S et al., Pediatrics 2006 Aug; 118:644-50
Budesonide plus Formoterol for Quick Relief of Persistent Asthma?
General Medicine
Summary and Comment
Rescue therapy with the budesonide-formoterol combination was superior to formoterol alone.
By Bruce Soloway, MD
September 28, 2006
Covering:
Rabe KF et al., Lancet 2006 Aug 26; 368:744-53
Pedersen S., Lancet 2006 Aug 26; 368:707-8
Count Your Doses the Inhaler May Be Empty!
One fourth of bronchodilator users reported finding their inhaler empty during an acute asthmatic attack.
By F. Bruder Stapleton, MD
September 27, 2006
Covering:
Sander N et al., Ann Allergy Asthma Immunol 2006 Jul; 97:34-8
The Value of Office Spirometry in Children
General Medicine
Summary and Comment
FEV1 can predict risk for future asthma symptoms.
By Howard Bauchner, MD
September 14, 2006
Covering:
Fuhlbrigge AL et al., Pediatrics 2006 Aug; 118:e347-55
Do Prebiotics Prevent Atopic Dermatitis in Infants?
Dermatology
Summary and Comment
Investigators added prebiotics to infant formula in an attempt to reproduce the preventive effects of breast-feeding on atopic dermatitis.
By Mary Wu Chang, MD
August 25, 2006
Covering:
Moro G et al., Arch Dis Child 2006 Jul 27
Atopic Dermatitis Peeling the Onion
A useful and thorough overview of the latest findings on atopic dermatitis and recommendations for clinicians
By Lowell A. Goldsmith, MD, MPH
August 4, 2006
Long-Acting Inhaled ß-Agonists and Mortality
General Medicine
Summary and Comment
Free
A meta-analysis provides evidence on deaths related to long-acting ß-agonist use for asthma.
By Richard Saitz, MD, MPH, FACP, FASAM
July 18, 2006
Covering:
Salpeter SR et al., Ann Intern Med 2006 Jun 20; 144:904-12
Glassroth J., Ann Intern Med 2006 Jun 20; 144:936-7
Do Inhaled Steroids Affect Progression of Mild Asthma?
General Medicine
Summary and Comment
These results do not settle the controversy about the effect of inhaled corticosteroids on long-term lung function in asthma.
By Allan S. Brett, MD
July 13, 2006
Covering:
O'Byrne PM et al., Chest 2006 Jun; 129:1478-85
Pediatric Asthma Managing the Environment
Educational guidelines that contain important information about the environmental management of asthma
By Howard Bauchner, MD
July 6, 2006
Covering:
The National Environmental Education and Training Foundation., 2005 Aug
Can Early Inhaled Steroids Modify the Course of Asthma in Children?
Early treatment in preschoolers did not alter the course of asthma.
By Howard Bauchner, MD
June 9, 2006
Covering:
Guilbert TW et al., N Engl J Med 2006 May 11; 354:1985-97
Bisgaard H et al., N Engl J Med 2006 May 11; 354:1998-2005
Gold DR and Fuhlbrigge AL., N Engl J Med 2006 May 11; 354:2058-60
Improving Asthma Care in Children
General Medicine
Summary and Comment
Physician education seminars led to improved patient outcomes.
By Howard Bauchner, MD
June 16, 2006
Covering:
Cabana MD et al., Pediatrics 2006 Jun; 117:2149-57
Esomeprazole Therapy for Asthma: Marginal Benefit
General Medicine
Summary and Comment
Free
Asthma patients received little benefit from potent acid suppression.
By Allan S. Brett, MD
June 6, 2006
Covering:
Kiljander TO et al., Am J Respir Crit Care Med 2006 May 15; 173:1091-7