Bubbly Fingers
Dermatology
Summary and Comment
Free
A very thorough study of pompholyx and recommendations on what to do next
By Mark V. Dahl, MD
February 1, 2008
Covering:
Guillet MH et al., Arch Dermatol 2007 Dec; 143:1504
Storrs FJ., Arch Dermatol 2007 Dec; 143:1578
A Role for Platelet-Activating Factor in Anaphylaxis
Dermatology
Summary and Comment
Findings suggest new avenues for the diagnosis, monitoring, and treatment of severe anaphylactic responses.
By Craig A. Elmets, MD
January 25, 2008
Covering:
Vadas P et al., N Engl J Med 2008 Jan 3; 358:28
Burks AW., N Engl J Med 2008 Jan 3; 358:79
Foot Dermatitis: A Shoe-In
Dermatology
Summary and Comment
Patch testing can help wearers give the boot to footwear with troublesome allergens.
By Mark V. Dahl, MD
January 18, 2008
Covering:
Warshaw EM et al., Dermatitis 2007 Dec; 18:191
Calcium Channel Blockers Can Cause Chronic Eczematous Rash
General Medicine
Summary and Comment
Calcium channel blockers were the only drug class significantly associated with eczematous rash.
By Allan S. Brett, MD
January 10, 2008
Covering:
Joly P et al., J Invest Dermatol 2007 Dec; 127:2766
Natural History of Asthma
General Medicine
Summary and Comment
Use of health services shortly after diagnosis was the strongest predictor of persistent disease.
By Howard Bauchner, MD
January 3, 2008
Covering:
To T et al., Arch Pediatr Adolesc Med 2007 Dec; 161:1197
Natural History of Egg Allergy
General Medicine
Summary and Comment
Most children develop tolerance by late childhood.
By Howard Bauchner, MD
January 2, 2008
Covering:
Savage JH et al., J Allergy Clin Immunol 2007 Dec; 120:1413
Do Calcium Channel Blockers Cause Chronic Eczema in Elderly Adults?
Dermatology
Summary and Comment
CCB treatment was significantly associated with eczema of unexplained origin that resolved when the drug was withdrawn.
Hypertonic Saline for Bronchiolitis
Nebulized hypertonic saline reduced hospital length of stay in young children with bronchiolitis.
By Cornelius W. Van Niel, MD
November 7, 2007
Covering:
Kuzik BA et al., J Pediatr 2007 Sep; 151:266
Calogero C and Sly PD., J Pediatr 2007 Sep; 151:235
Can Diet Prevent Atopic Disease in Infants?
General Medicine
Summary and Comment
More evidence supports long-term breast-feeding but does not support delaying the introduction of any (even allergenic) food after 6 months of age.
By Robert A. Dershewitz, MD, MSc
November 6, 2007
Covering:
Snijders BEP et al., J Pediatr 2007 Oct; 151:347
Filipiak B et al., J Pediatr 2007 Oct; 151:352
Hill DJ et al., J Pediatr 2007 Oct; 151:359
Sicherer SH., J Pediatr 2007 Oct; 151:331
All That Forms Rings Is Not Erythema Multiforme
Dermatology
Summary and Comment
Free
Acute annular urticaria is common in childhood, benign, and self-limiting, but the lesions can be misleading.
By Mary Wu Chang, MD
November 2, 2007
Covering:
Shah KN et al., Pediatrics 2007 May; 119:e1177
Greasing the Tub and Skin
Dermatology
Summary and Comment
For atopic dermatitis, it is probably more effective to rub on skin emollients than to soak in them.
New Asthma Guidelines
Pediatrics and Adolescent Medicine
Clinical Practice Guideline Watch
Free
The guidelines include new sections for asthma management in children ages 0 to 4 and 5 to 11 years.
By Howard Bauchner, MD
October 31, 2007
Covering:
National Heart, Lung, and Blood Institute., 2007 Aug 28
Does Neonatal Airway Colonization Cause Asthma?
Colonization at 1 month was significantly associated with development of persistent wheeze and asthma by age 5.
By Howard Bauchner, MD
October 10, 2007
Covering:
Bisgaard H et al., N Engl J Med 2007 Oct 11; 357:1487
von Mutius E., N Engl J Med 2007 Oct 11; 357:1545
A Link Between Eosinophilic Esophagitis and Celiac Disease?
Gastroenterology
Summary and Comment
In a case series of 17 children with EoE, 6 had celiac disease; after switching to gluten-free diets, all 6 had complete resolution of their presenting EoE complaints.
By David A. Johnson, MD
September 21, 2007
Covering:
Quaglietta L et al., Aliment Pharmacol Ther 2007 Aug 1; 26:487
Is Transient Tachypnea of the Newborn Really Transient?
Infants with TTN might be more likely to wheeze later in childhood.
Think of Workplace Exposure in New-Onset Adult Asthma
Emergency Medicine
Summary and Comment
Occupational exposure leads to more than 10% of cases of new-onset asthma in adults.
Exhaled Nitric Oxide — Guidance for Asthma Management?
General Medicine
Summary and Comment
Patients whose steroid dosing was determined by nitric oxide levels did not have better outcomes than those whose dosing followed standard guidelines.
By Allan S. Brett, MD
August 7, 2007
Covering:
Shaw DE et al., Am J Respir Crit Care Med 2007 Aug 1; 176:231-7
Travers J et al., Am J Respir Crit Care Med 2007 Aug 1; 176:238-42
A Controlled Clinical Trial of Steroids for Bronchiolitis
One dose of oral dexamethasone was no different from placebo.
By Howard Bauchner, MD
July 25, 2007
Covering:
Corneli HM et al., N Engl J Med 2007 Jul 26; 357:331-9
Antibiotic Use Early in Life Increases Risk for Asthma
This population-based study confirms previous studies that found an association between antibiotic use and development of childhood asthma.
By F. Bruder Stapleton, MD
July 18, 2007
Covering:
Kozyrskyj AL et al., Chest 2007 Jun; 131:1753-9
The Childhood Atopic Dermatitis Impact Scale: CADIS Comes of Age
Dermatology
Summary and Comment
Free
This subjective parental assessment tool yielded results that were comparable to and more easily obtained than SCORAD system assessments.
By Mary Wu Chang, MD
July 13, 2007
Covering:
Chamlin SL et al., Arch Dermatol 2007 Jun; 143:768-72
Mycophenolate Mofetil for Childhood Atopic Dermatitis
Dermatology
Summary and Comment
MMF may be costly, but it appears to be an effective, alternative immunosuppressive agent for severe pediatric atopic dermatitis.
By Jeffrey P. Callen, MD
July 13, 2007
Covering:
Heller M et al., Br J Dermatol 2007 Jul; 157:127-32
Hashing Out Allergic Contact Dermatitis Another Medical Use for Marijuana?
Dermatology
Summary and Comment
Free
Cannabinoids, endogenous and exogenous, suppressed contact dermatitis reactions in mouse ears.
By Mark V. Dahl, MD
June 22, 2007
Covering:
Karsak M et al., Science 2007 Jun 8; 316:1494-7
Reducing the Intensity of Treatment in Mild Asthma
General Medicine
Summary and Comment
Free
Two randomized trials demonstrate the feasibility of step-down therapy in patients whose asthma is well controlled.
By Allan S. Brett, MD
May 16, 2007
Covering:
The American Lung Association Asthma Clinical Research Centers., N Engl J Med 2007 May 17; 356:2027-39
Papi A et al., N Engl J Med 2007 May 17; 356:2040-52
Telemedicine for Asthma Management
Outcomes of internet- and office-based asthma care were similar.
By Cornelius W. Van Niel, MD
April 4, 2007
Covering:
Chan DS et al., Pediatrics 2007 Mar; 119:569-78
Living Near a Freeway Restricts Lung Development in Children
General Medicine
Summary and Comment
Children living near freeways likely have impaired lung function for life.
By Bruce Soloway, MD
March 6, 2007
Covering:
Gauderman WJ et al., Lancet 2007 Feb 17; 369:571-7