Serologic Test for Dermatitis Herpetiformis
Dermatology Summary and Comment
Progressive expansion of the epitope-binding profile of IgA antitransglutaminase antibodies in patients with gluten sensitivity may explain the eventual development of dermatitis herpetiformis in some.
By Mark V. Dahl, MD
October 10, 2008
Covering:
Hull CM et al., Br J Dermatol 2008 Jul; 159:120
Does Measuring Exhaled Nitric Oxide Improve Asthma Care in Adolescents?
General Medicine Summary and Comment
Monitoring exhaled nitric oxide did not improve symptoms or lung function in this randomized controlled study.
By Howard Bauchner, MD
September 30, 2008
Covering:
Szefler SJ et al., Lancet 2008 Sep 20; 372:1065
Acetaminophen and Asthma in Children
General Medicine Summary and Comment
Retrospective results suggest a relation between acetaminophen use in infancy and development of asthma.
By Howard Bauchner, MD
September 25, 2008
Covering:
Beasley R et al., Lancet 2008 Sep 20; 372:1039
Barr RG., Lancet 2008 Sep 20; 372:1011
Is Acetaminophen Use Linked to Asthma in Young Children?
The results of this retrospective study suggest an association but do not establish a causal relation.
By F. Bruder Stapleton, MD
September 24, 2008
Covering:
Beasley R et al., Lancet 2008 Sep 20; 372:1039
Barr RG., Lancet 2008 Sep 20; 372:1011
Long-Term Use of Synbiotics Is Safe
A large randomized trial confirms the safety of prenatal probiotic exposure and synbiotic exposure in healthy young infants.
Roach Rash
Dermatology Summary and Comment
Cockroach and dust mite antigens disrupt the skin barrier.
By Mark V. Dahl, MD
September 12, 2008
Covering:
Jeong SK et al., J Invest Dermatol 2008 Aug; 128:1930
Roelandt T et al., J Invest Dermatol 2008 Aug; 128:1878
Do Moisturizers Promote the Development of Nonmelanoma Skin Cancers?
Dermatology Summary and Comment
Free
The findings have been widely reported in the press, but the evidence is not definitive, and applicability remains to be proved.
By Craig A. Elmets, MD
September 5, 2008
Covering:
Lu Y-P et al., J Invest Dermatol 2008 Aug 14
Naltrexone Linked to Injection-Site Reactions
Nearly 200 people receiving extended-release naltrexone (Vivitrol) have reported adverse injection-site reactions, including cellulitis, induration, hematoma, abscess, sterile abscess, and necrosis, the FDA...
Does My Wheezing Preschooler Have Asthma?
Emergency Medicine Summary and Comment
History of atopy and exercise-induced asthma predicted persistent asthma in preschool children with wheeze.
Wheezing with Filaggrin Mutations
Dermatology Summary and Comment
Children with these mutations are prone to eczema, rhinitis, allergic sensitization, and, sometimes, asthma.
By Mark V. Dahl, MD
July 11, 2008
Covering:
Weidinger S et al., J Allergy Clin Immunol 2008 May; 121:1203
Is H. Pylori Infection Protective Against Asthma and Allergies?
Gastroenterology Summary and Comment
The decreasing prevalence of <$EMPH_O>H. pylori<$EMPH_C> in children might be associated with epidemics of asthma and related allergy disorders.
Associations Between Eosinophilic Esophagitis and Atopic Diathesis
Gastroenterology Summary and Comment
All patients with EoE diagnoses should receive comprehensive allergy testing.
By David A. Johnson, MD
June 20, 2008
Covering:
Roy-Ghanta S et al., Clin Gastroenterol Hepatol 2008 May; 6:531
Inhalers and the Ozone Layer
Chlorofluorocarbon-propelled albuterol inhalers will no longer be available after December 31, 2008, and will be replaced by hydrofluoroalkane-propelled inhalers.
By Howard Bauchner, MD
June 18, 2008
Covering:
U.S. Food and Drug Administration.,
Rockville, MD: Food and Drug Administration 2008 May 30U.S. Food and Drug Administration.,
Use of Soy-Based Formulas in Infants: Myths, Misuse, and Misconceptions
An updated clinical report reviews the contraindications and limited indications for soy formula in infants.
Coexisting Conditions and Management of Hypertension
Cardiology Summary and Comment
In a population-based cohort, the more unrelated comorbidities patients had, the less likely they were to receive intensified treatment for uncontrolled hypertension.
By Joel M. Gore, MD
May 21, 2008
Covering:
Turner BJ et al., Ann Intern Med 2008 Apr 15; 148:578
Illuminating the Relation Between Polymorphous Light Eruption and Lupus
Dermatology Summary and Comment
Contrary to expectations, no patients with PMLE progressed to cutaneous lupus during a relatively long follow-up period.
By Craig A. Elmets, MD
May 2, 2008
Covering:
Tzaneva S et al., Br J Dermatol 2008 May; 158:1050
Is Aspirin an Answer for Asthma?
Women's Health Summary and Comment
Women taking low-dose aspirin had 10% reduction in risk for new-onset asthma during 10 years of follow-up.
Improving Asthma Outcomes in Black and Hispanic Children
Parents’ attitudes about illness, treatment, and outcomes differ by ethnicity.
Looking Far Afield . . .
Interesting and amusing notes from the borderlands of dermatology
Nephrogenic Systemic Fibrosis: The Story Continues
Dermatology Summary and Comment
The link between this relatively new entity and gadodiamide exposure has been confirmed.
Review of Atopic Dermatitis
Dermatology Summary and Comment
Free
A comprehensive look at this common but complicated condition
By Mary Wu Chang, MD
April 2, 2008
Covering:
Bieber T., N Engl J Med 2008 Apr 3; 358:1483
Written Action Plans for Children with Asthma
General Medicine Summary and Comment
Symptom-based plans lowered risk for acute care and peak-flow–based plans reduced the number of symptomatic days, but most outcomes were similar.
By Howard Bauchner, MD
February 26, 2008
Covering:
Zemek RL et al., Arch Pediatr Adolesc Med 2008 Feb; 162:157
Early Nutrition and Development of Atopic Disease
Pediatrics and Adolescent Medicine Clinical Practice Guideline Watch
Free
A new clinical report from the AAP found little evidence that dietary interventions after age 4 to 6 months prevent atopic disease in early life.
By Howard Bauchner, MD
February 20, 2008
Covering:
Greer FR et al., Pediatrics 2008 Jan; 121:183
Can We Prevent Atopic Disease by What We Feed Our Babies?
Dermatology Summary and Comment
Free
Mothers-to-be and breast-feeding mothers need not restrict their food choices, but they should plan on breast-feeding exclusively for the first 4 months, if possible.
By Mary Wu Chang, MD
February 15, 2008
Covering:
Greer FR et al., Pediatrics 2008 Jan; 121:183
Which New Medications May Cause SJS or TEN?
Dermatology Summary and Comment
A useful summary of which drugs are most likely to cause these severe adverse reactions
By Jeffrey P. Callen, MD
February 15, 2008
Covering:
Mockenhaupt M et al., J Invest Dermatol 2008 Jan; 128:35
Halevy S et al., J Am Acad Dermatol 2008 Jan; 58:25
