Conservative Management of Localized Prostate Cancer
Disease surveillance might be appropriate in certain men.
Neuroimaging with Pittsburgh Compound B in Patients with Mild Cognitive Impairment
Neurology Summary and Comment
MCI patients with amyloid retention identified by PiB most likely have very early AD.
By Rawan Tarawneh, MD, and John C. Morris, MD
October 13, 2009
Covering:
Wolk DA et al., Ann Neurol 2009 May; 65:557
Dermatology Summary and Comment
Free
Insufficient tumor necrosis factor affected the ability of T lymphocytes to migrate to the skin.
By Craig A. Elmets, MD
October 9, 2009
Covering:
Agius E et al., J Exp Med 2009 Aug 31; 206:1929
Antibiotic Guideline Compliance and Outcomes for CAP
Emergency Medicine Summary and Comment
Two large studies support guideline-based care.
By J. Stephen Bohan, MD, MS, FACP, FACEP
October 9, 2009
Covering:
McCabe C et al., Arch Intern Med 2009 Sep 14; 169:1525
Arnold FW et al., Arch Intern Med 2009 Sep 14; 169:1515
Sharpe BA., Arch Intern Med 2009 Sep 14; 169:1462
Screening Test for Stroke-Related Dysphagia
General Medicine Summary and Comment
Most patients who had problems swallowing in the ED had dysphagia on formal evaluations by speech pathologists.
By Allan S. Brett, MD
October 8, 2009
Covering:
Turner-Lawrence DE et al., Ann Emerg Med 2009 Sep; 54:344
Surgery vs. Noninvasive Therapy for Carpal Tunnel Syndrome
General Medicine Summary and Comment
Surgery was more effective than other noninvasive therapies, but either treatment modality benefited patients.
By Bruce Soloway, MD
October 8, 2009
Covering:
Jarvik JG et al., Lancet 2009 Sep 26; 374:1074
Management of Chronic Pain
Comprehensive treatment for chronic pain must address both physical and psychological aspects.
By Lynn Rader, MD
October 8, 2009
Topical Voltaren Gel for Hand Osteoarthritis
General Medicine Summary and Comment
Diclofenac gel was better than placebo for relieving pain.
By Allan S. Brett, MD
October 6, 2009
Covering:
Altman RD et al., J Rheumatol 2009 Sep; 36:1991
Is Clinical Breast Examination, Added to Mammography, Worthwhile?
General Medicine Summary and Comment
CBE was associated with 55 additional false-positives for each additional breast cancer detected.
By Allan S. Brett, MD
October 1, 2009
Covering:
Chiarelli AM et al., J Natl Cancer Inst 2009 Sep 16; 101:1236
Walking Program for Patients with Impaired Glucose Tolerance
General Medicine Summary and Comment
Pedometer use resulted in more walking and lower glucose levels.
Cardiac Surgery in Patients with Carotid Stenosis
General Medicine Summary and Comment
Combining endarterectomy with cardiac surgery did not prevent perioperative strokes.
By Allan S. Brett, MD
October 1, 2009
Covering:
Li Y et al., Arch Neurol 2009 Sep; 66:1091
Maintaining Mental Fitness in Old Age
Neurology Summary and Comment
What factors affect maintenance of cognitive function or contribute to cognitive decline?
By Kirk R. Daffner, MD
September 29, 2009
Covering:
Yaffe K et al., Neurology 2009 Jun 9; 72:2029
Long-Term Relief of Poststroke Depression
Psychiatry Summary and Comment
Brief interventions that educate patients and teach a problem-solving approach might have a long-lived effect.
By Jonathan Silver, MD
September 28, 2009
Covering:
Mitchell PH et al., Stroke 2009 Sep; 40:3073
Overdiagnosis in PSA Screening
General Medicine Summary and Comment
An analysis suggests that many men have been treated unnecessarily because of PSA screening.
By Allan S. Brett, MD
September 24, 2009
Covering:
Welch HG and Albertsen PC., J Natl Cancer Inst 2009 Aug 31
Brawley OW., J Natl Cancer Inst 2009 Aug 31
CT Screening for Lung Cancer: Early Results
General Medicine Summary and Comment
Preliminary outcomes from the DANTE trial show no differences between screening and control groups.
By Allan S. Brett, MD
September 24, 2009
Covering:
Infante M et al., Am J Respir Crit Care Med 2009 Sep 1; 180:445
Radiofrequency Catheter Ablation for Atrial Fibrillation
General Medicine Summary and Comment
This procedure is effective as a second-line treatment in selected patients.
Sex Hormone–Binding Globulin Is Linked to Type 2 Diabetes Risk
General Medicine Summary and Comment
Circulating SHBG levels predicted risk beyond that associated with traditional factors.
By Robert W. Rebar, MD
September 22, 2009
Covering:
Ding EL et al., N Engl J Med 2009 Sep 17; 361:1152
Clodronate for Prostate Cancer: An Update
Long-term results revealed an overall survival benefit for men with metastatic, but not locally advanced, disease.
Prostate Cancer Mortality After Radical Prostatectomy
Predicting disease-specific mortality on the basis of standard clinical parameters is still difficult.
Inhibition of APP Secretases as a Therapy for Traumatic Brain Injury
Neurology Summary and Comment
APP secretase inhibitors, currently in AD clinical trials, may prove effective in treating TBI, as may other interventions that reduce amyloid-beta levels.
By Milos D. Ikonomovic, MD, and Steven T. DeKosky, MD
September 22, 2009
Covering:
Loane DJ et al., Nat Med 2009 Apr; 15:377
"Timing Hypothesis" for Hormone Therapy: Still Viable, or Time to Let Go?
In a new analysis, researchers examine outcomes associated with HT use in the early postmenopausal period.
Evaluating Syncopal Episodes in Elders
General Medicine Summary and Comment
Start with simple inexpensive tests, such as postural blood pressure measurement.
Physician Recommendations to Limit Life Support — What Do Surrogates Want?
General Medicine Summary and Comment
And when are physicians obligated to offer a recommendation?
By Allan S. Brett, MD
September 17, 2009
Covering:
White DB et al., Am J Respir Crit Care Med 2009 Aug 15; 180:320
Warfarin for Stroke Prevention in Patients with Atrial Fibrillation
Cardiology Summary and Comment
Results of a large observational study provide current data for accurate risk-benefit estimation.
By Joel M. Gore, MD
September 16, 2009
Covering:
Singer DE et al., Ann Intern Med 2009 Sep 1; 151:297
Does Hormonal Therapy for Prostate Cancer Raise Mortality Risk?
Neoadjuvant androgen-deprivation therapy was associated with higher rates of all-cause mortality only in patients with coronary artery disease.
