Aging / Geriatrics: Archives

More Data on Aromatase Inhibitors for Breast Cancer

• General Medicine
• Summary and Comment
• Subscription required

Extending endocrine therapy beyond 5 years prevents some breast cancer relapses.

• By Allan S. Brett, MD
• May 8, 2008
• Covering:
  • Muss HB et al., J Clin Oncol 2008 Apr 20; 26:1956
  • Mamounas EP et al., J Clin Oncol 2008 Apr 20; 26:1965
  • Goss PE et al., J Clin Oncol 2008 Apr 20; 26:1948

Prophylactic Implantable Cardioverter-Defibrillators?

• Cardiology
• Summary and Comment
• Subscription required

A finding that inappropriate ICD shocks are associated with increased mortality raises a chicken-or-egg question.

• By Mark S. Link, MD
• April 30, 2008
• Covering:
  • Daubert JP et al., J Am Coll Cardiol 2008 Apr 8; 51:1357
  • Raitt MH., J Am Coll Cardiol 2008 Apr 8; 51:1366

Adenoma Recurrence and Guidelines for Surveillance After Polypectomy

• General Medicine
• Summary and Comment
• Subscription required

At 4 years, advanced adenomas were detected in 9% of high-risk patients but also in 5% of low-risk patients.

• By Richard Saitz, MD, MPH, FACP, FASAM, and Allan S. Brett, MD
• April 29, 2008
• Covering:
  • Laiyemo AO et al., Ann Intern Med 2008 Mar 18; 148:419
  • Imperiale TF and Sox HC., Ann Intern Med 2008 Mar 18; 148:477

Do Disease Management Programs Really Make a Difference in Heart Failure?

• Cardiology
• Summary and Comment
• Subscription required

A randomized trial of three programs of varying intensity did not reveal any significant differences in outcomes.

• By William T. Abraham, MD
• April 23, 2008
• Covering:
  • Jaarsma T et al. for the COACH Investigators., Arch Intern Med 2008 Feb 11; 168:316

Extranasal MRSA Colonization in Nursing Home Residents

• Infectious Diseases
• Summary and Comment
• Subscription required

Colonization with MRSA at groin and perianal sites was significantly more common in residents with indwelling catheters than in those without such devices.

• By Neil M. Ampel, MD
• April 23, 2008
• Covering:
  • Mody L et al., Clin Infect Dis 2008 May 1; 46:1368

Prostate Cancer Mortality in the U.S. and U.K.: Effect of PSA Screening

• Oncology and Hematology
• Summary and Comment
• Subscription required

Rates of PSA testing and types of therapy for early prostate cancer from 1975 through 2003 were analyzed for both countries.

• By Robert Dreicer, MD, MS, FACP
• April 22, 2008
• Covering:
  • Collin SM et al., Lancet Oncol 2008 Apr 17

Should We Treat Hypertension in Very Old People?

• General Medicine
• Summary and Comment
• Subscription required

In the HYVET, relatively healthy octogenarians benefited from antihypertensive therapy.

• By Allan S. Brett, MD
• April 17, 2008
• Covering:
  • Beckett NS et al., N Engl J Med 2008 Mar 31
  • Kostis JB., N Engl J Med 2008 Mar 31

Disparity of Surgical Care in Patients with Early-Stage Breast Cancer

• Oncology and Hematology
• Summary and Comment
• Free

Awareness is the first step toward eliminating racial, ethnic, and socioeconomic factors in surgical treatment.

• By Henry Mark Kuerer, MD, PhD, FACS
• April 15, 2008
• Covering:
  • Chen AY et al., J Natl Cancer Inst 2008 Apr 2; 100:462

Do Patients with Familial Prostate Cancer Have Worse Outcomes?

• Oncology and Hematology
• Summary and Comment
• Subscription required

Father–son pairs shared good or poor prognoses.

• By Robert Dreicer, MD, MS, FACP
• April 15, 2008
• Covering:
  • Hemminki K et al., J Clin Oncol 2008 Apr 1; 26:1705

Are Antihypertensive Drugs Neuroprotective in Parkinson Disease?

• Neurology
• Summary and Comment
• Subscription required

A large case-control study suggests that calcium channel blockers are the only antihypertensives that reduce the risk for Parkinson disease.

• By Robert L. Rodnitzky, MD
• April 15, 2008
• Covering:
  • Becker C et al., Neurology 2008 Feb 6