From the publishers of The New England Journal of Medicine

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STDs

The latest information on sexually transmitted diseases — summaries and comments on Chlamydia, gonorrhea, herpes, HIV, HPV, syphilis, and more — drawn from across our primary care and specialty care areas. Sign up now for monthly e-mail alerts on new content.

SUMMARY AND COMMENT

Oral HPV Infection Is CommonFree

Such infection — associated with a form of oropharyngeal squamous cell carcinoma — is present in 6.9% of the U.S. population aged 14 to 69.

SUMMARY AND COMMENT

Recent Patterns of Anal Cancer in HIV-Infected Patients

Rates exceed those in the general population for all risk groups but are highest among men who have sex with men.

SUMMARY AND COMMENT

Testing Midstream Urine for Chlamydia trachomatis

Midstream samples might be adequate for evaluating both chlamydial and urinary tract infections, but study results were not definitive.

SUMMARY AND COMMENT

High-Dose Antivirals Do Not Fully Suppress Reactivation of Genital Herpes Simplex

Suppressive therapy is not adequate for preventing transmission.

SUMMARY AND COMMENT

New Approach to Immunizing Against HIV Is Dramatically Effective in Mice

Vectored immunoprophylaxis delivers genes that encode HIV-neutralizing antibodies.

SUMMARY AND COMMENT

Oral and Fingerstick Sample Collection for HIV Screening: Subtle but Important Differences in Accuracy

The OraQuick rapid HIV test performed well on both types of samples but was less sensitive and specific on oral fluid, which would lead to a lower positive predictive value in low-prevalence settings.

FEATURE

Pre-Super Sunday ScombroidsFree

From doctors cheating Medicaid to older men contracting HIV, Dr. Paul Sax offers his take on the week's ID news in his blog HIV/ID Observations.

SUMMARY AND COMMENT

A Combined HIV Antigen/Antibody Rapid Test Fails Field Evaluation

Diagnosis of acute HIV infection remains elusive.

SUMMARY AND COMMENT

Is HIV Becoming More Virulent?

A meta-analysis suggests that over the course of the epidemic, the mean virologic set point of HIV-infected patients has been increasing and the mean baseline CD4-cell count has been decreasing.

VACCINE WATCH

Quadrivalent Human Papillomavirus Vaccine Now for Males, TooFree

New recommendations — for males — include routine use of HPV4 at ages 11 or 12 years and vaccination through age 26 for those who have not completed the three-dose series.

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