Skin Cancer
The latest information on basal cell carcinoma, chemotherapy, melanoma, squamous cell carcinoma, and more, drawn from across our primary care and specialty care areas. Sign up now for monthly e-mail alerts on new content.
SUMMARY AND COMMENT
Basal Cell Carcinoma at a Young Age: Another Consequence of Tanning BedsFree
- February 3, 2012
- Craig A. Elmets, MD
- Dermatology
Tanning bed users younger than 40 developed early-onset BCCs significantly more often than nonusers.
- Reviewing:
- Ferrucci LM et al. J Am Acad Dermatol 2011 Dec 8
SUMMARY AND COMMENT
Vitamin D and Calcium Supplements: What Do the Data Show? Who Should Be Treated?
- January 27, 2012
- Craig A. Elmets, MD
- Dermatology
Vitamin D and calcium supplementation may lower fracture risk in some individuals, but data regarding its effects on cancer are inconclusive.
- Reviewing:
- Chung M et al. Ann Intern Med 2011 Dec 20; 155:827
SUMMARY AND COMMENT
Adnexal Tumor: Useful Information in a Pathology Report
- January 27, 2012
- Angelica Selim, MD
- Dermatology
Pagetoid spread and an infiltrative growth pattern suggest the need for extended excision of some eccrine porocarcinomas.
- Reviewing:
- Belin E et al. Br J Dermatol 2011 Nov; 165:985
SUMMARY AND COMMENT
A Proposed Mechanism Behind SCC Formation in Vemurafenib RecipientsFree
- January 20, 2012
- Kenneth Y. Tsai, MD, PhD
- Dermatology
The presence of RAS mutations suggests that preexisting keratinocytes bearing these mutations are unmasked by vemurafenib
- Reviewing:
- Su F et al. N Engl J Med 2012 Jan 19; 366:207
SUMMARY AND COMMENT
Stem Cells on the Clock: Circadian Rhythm Proteins Regulate Epidermal Stem Cells
- January 20, 2012
- Kenneth Y. Tsai, MD, PhD
- Dermatology
Investigators found an association between expression of genes associated with stem cell function and expression of circadian rhythm genes.
- Reviewing:
- Janich P et al. Nature 2011 Dec 8; 480:209
SUMMARY AND COMMENT
Vitamin D and UVB Radiation: How Much Is Necessary?Free
- January 13, 2012
- Craig A. Elmets, MD
- Dermatology
For individuals unable to benefit from supplements, ultraviolet B exposure every 2 weeks may be an alternative.
- Reviewing:
- Bogh MKB et al. Br J Dermatol 2011 Oct 20
SUMMARY AND COMMENT
More Evidence That Combined Tacrolimus and Narrowband UVB Are Useful for VitiligoFree
- January 6, 2012
- Craig A. Elmets, MD
- Dermatology
Combined treatment was better than ultraviolet treatment alone, and the effects were tacrolimus dose-dependent.
- Reviewing:
- Nordal EJ et al. J Eur Acad Dermatol Venereol 2011 Dec; 25:1440
SUMMARY AND COMMENT
Granulomatous Processes and Clonality: PCR Evaluation of T-Cell Rearrangement for Diagnosis
- January 6, 2012
- Angelica Selim, MD
- Dermatology
Analysis of T-cell clonality is useful for differentiating sarcoidosis and primary granuloma annulare from granulomatous CTCLs.
- Reviewing:
- Pfaltz K et al. Am J Dermatopathol 2011 Oct; 33:659
SUMMARY AND COMMENT
How Effective Is Melanoma Screening?Free
- December 22, 2011
- Hensin Tsao, MD, PhD
- Dermatology
Melanoma mortality dropped significantly in one German state after a population-wide screening project, while mortality rates remained stable in the rest of Germany.
- Reviewing:
- Breitbart EW et al. J Am Acad Dermatol 2011 Nov 8
FEATURE
Behind the Numbers: Number Needed to Screen
- December 22, 2011
- Joel M. Gelfand, MD, MSCE
- Dermatology
Dr. Joel Gelfand elucidates the concept of number needed to screen in "Behind the Numbers", a new Journal Watch Dermatology feature aimed at clarifying issues in epidemiologic design and biostatistics.
