Skin Cancer
The latest information on basal cell carcinoma, chemotherapy, melanoma, squamous cell carcinoma, and more, drawn from across our primary care and specialty care areas. Sign up now for monthly e-mail alerts on new content.
SUMMARY AND COMMENT
PPAR for the Melanoma Course
- July 2, 2009
- Mark V. Dahl, MD
- Dermatology
Glitazones represent a new direction for developing molecularly targeted anticancer agents.
- Reviewing:
- Botton T et al. J Invest Dermatol 2009 May; 129:1208
SUMMARY AND COMMENT
Cutaneous Non–AIDS-Defining Cancers in HIV-Infected Individuals
- July 1, 2009
- Larry M. Baddour, MD
- Infectious Diseases
Such cancers are not associated with immune status or receipt of ART.
- Reviewing:
- Crum-Cianflone N et al. Arch Intern Med 2009 Jun 22; 169:1130
SUMMARY AND COMMENT
Ingenol Mebutate for Actinic KeratosesFree
- June 26, 2009
- George J. Hruza, MD
- Dermatology
A short course of this plant-based agent significantly improved AK clearance.
- Reviewing:
- Anderson L et al. J Am Acad Dermatol 2009 Jun; 60:934
SUMMARY AND COMMENT
Melanocytes in Lymph Nodes: BRAF Is Not the Answer
- June 5, 2009
- Angelica Selim, MD
- Dermatology
Evidence of BRAF mutation in sentinel node tissue is insufficient to diagnose metastasis, as this mutation also appears in benign nodal nevi.
- Reviewing:
- Taube JM et al. Am J Surg Pathol 2009 Apr; 33:568
SUMMARY AND COMMENT
Mice Capades
- June 5, 2009
- Hensin Tsao, MD, PhD
- Dermatology
Activating Braf mutation and silencing Pten in melanocytes provoked melanoma with metastasis in mice.
- Reviewing:
- Dankort D et al. Nat Genet 2009 May; 41:544
SUMMARY AND COMMENT
Heavy Metal in Melanoma
- June 5, 2009
- Hensin Tsao, MD, PhD
- Dermatology
Mutations that restricted the production of a matrix metalloprotein diminished tumor suppression and fostered aggressive characteristics in cancer cells.
- Reviewing:
- Palavalli LH et al. Nat Genet 2009 May; 41:518
SUMMARY AND COMMENT
A Potential Overcall: Recurrent Melanocytic Nevi
- May 29, 2009
- Angelica Selim, MD
- Dermatology
These lesions resemble malignant melanomas with regression, but clinical characteristics can help to differentiate the two.
- Reviewing:
- King R et al. Mod Pathol 2009 May; 22:611
FEATURE
Briefly Noted
- May 29, 2009
- Jeffrey P. Callen, MD
- Dermatology
Counseling patients at risk for melanoma, factors associated with malignancy in dermatomyositis, guidelines for safe use of methotrexate for psoriasis, and a new TNF-
antibody, administered by subcutaneous injection
FEATURE
Vitamin D and HealthFree
- May 22, 2009
- Dermatology
Do we have enough? How do we get more? What systems are affected?
SUMMARY AND COMMENT
Oncogenic Lesions in LentiginesFree
- May 15, 2009
- Hensin Tsao, MD, PhD
- Dermatology
Researchers establish a genetic link between keratoses and lentigines, but not all mutations lead to cancer.
- Reviewing:
- Hafner C et al. Br J Dermatol 2009 Mar; 160:546
