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Peptic Ulcers

The latest information on acid reflux, GERD, H. pylori, proton-pump inhibitors, and more, drawn from across our primary care and specialty care areas. Sign up now for monthly e-mail alerts on new content.

Settings for Bipolar Electrocoagulation

Optimal clinical technique involves lower watt settings of moderately long duration, and application force is needed to coagulate vessels.

Local vs. Systemic Effects of Aspirin

Which is more causal to peptic ulcers?

Timing of H. Pylori Therapy in Gastric Cancer

Is Helicobacter pylori eradication therapy more effective before or after surgery in gastric cancer patients?

Does Omeprazole Affect Antiplatelet Therapy?

Circumstantial evidence shows that coadministration of clopidogrel and PPIs can affect platelet reactivity.

Proton-Pump Inhibitors to Prevent NSAID Complications

Risk for upper GI events was higher when NSAIDs or coxibs were prescribed without PPIs.

Idiopathic Duodenal Ulcers and Duodenal H. pylori Infection

Duodenal H. pylori infection may account for a substantial number of duodenal ulcers that previously were classified as idiopathic.

Gastroprotective Cotherapy or Coxibs to Prevent Ulcer Hospitalizations in NSAID Users?

Findings show that PPIs are as effective as coxibs in preventing NSAID-related gastropathy.

Endoscopic Dilation with Medical Therapy for Benign Gastric-Outlet Obstruction

Most patients in this small study underwent multiple dilations and received long-term acid-suppression therapy.

Acid Reduction After Endoscopic Mucosal Dissection

PPIs worked better than H2RAs for lowering bleeding risk among patients who underwent endoscopic removal of early gastric cancers.

GI Safety of COX-2 Inhibitors: Cochrane Collaboration Systematic Review

Adverse GI events are less common with COX-2 inhibitors than with NSAIDs, but we still have to weigh overall harms and benefits before prescribing these agents.

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