Pediatric Infections
The latest information on antibiotics, bronchitis, otitis media, pneumonia, and more, drawn from across our primary care and specialty care areas. Sign up now for monthly e-mail alerts on new content.
SUMMARY AND COMMENT
Nosocomial Measles Outbreak
- February 1, 2012
- Stephen G. Baum, MD
- Infectious Diseases
Measles, contracted in a hospital emergency department, affected both unimmunized and previously vaccinated individuals.
- Reviewing:
- Centers for Disease Control and Prevention (CDC). MMWR Morb Mortal Wkly Rep 2012 Jan 20; 61:30
SUMMARY AND COMMENT
Global Burden of Infant Group B Streptococcal Disease
- February 1, 2012
- Robert S. Baltimore, MD
- Infectious Diseases
In a meta-analysis of global data, incidence and fatality rates differed among countries, but the underlying serotypes were similar.
- Reviewing:
- Edmond KM et al. Lancet 2012 Jan 5
SUMMARY AND COMMENT
Preventing Serogroup B Meningococcal Disease
- January 25, 2012
- Mary E. Wilson, MD
- Infectious Diseases
In a phase IIB/III study conducted among adolescents in Chile, a multicomponent vaccine — 4CMenB — was immunogenic and safe.
- Reviewing:
- Santolaya ME et al. Lancet 2012 Jan 18
SUMMARY AND COMMENT
Influenza in Neurologically Compromised Patients
- January 25, 2012
- Stephen G. Baum, MD
- Infectious Diseases
An outbreak of influenza in patients with incapacitating neurological conditions caused severe infection, despite immunization.
- Reviewing:
- Centers for Disease Control and Prevention (CDC). MMWR Morb Mortal Wkly Rep 2012 Jan 6; 60:1729
SUMMARY AND COMMENT
FCGR2A as a Susceptibility Locus for Kawasaki Disease
- January 20, 2012
- Kenneth Y. Tsai, MD, PhD
- Dermatology
A genome-wide association study points to a susceptibility locus linking Kawasaki disease to an immune mediator.
- Reviewing:
- Khor CC et al. Nat Genet 2011 Nov 13; 43:1241
SUMMARY AND COMMENT
Helium-Oxygen Therapy Improves Bronchiolitis Scores in Infants Receiving Nebulized Epinephrine
- January 20, 2012
- Katherine Bakes, MD
- Emergency Medicine
Improvement was noted on each of two validated severity scores.
- Reviewing:
- Kim IK et al. Arch Pediatr Adolesc Med 2011 Dec; 165:1115
SUMMARY AND COMMENT
Single-Dose Azithromycin Efficacious Against Yaws
- January 18, 2012
- Mary E. Wilson, MD
- Infectious Diseases
Among children with yaws in Papua New Guinea, oral azithromycin was noninferior to intramuscular penicillin at 6-month follow-up.
- Reviewing:
- Mitjà O et al. Lancet 2012 Jan 11
SUMMARY AND COMMENT
Combination Corticosteroid plus IVIG for Treatment-Resistant Kawasaki Disease
- January 13, 2012
- Mary Wu Chang, MD
- Dermatology
Adding methylprednisolone to IV immunoglobulin eliminated fever and led to greater coronary artery dimension in children predicted to be IVIG-resistant.
- Reviewing:
- Ogata S et al. Pediatrics 2011 Dec 5
VACCINE WATCH
Quadrivalent Human Papillomavirus Vaccine Now for Males, TooFree
- January 11, 2012
- Robert S. Baltimore, MD
- Infectious Diseases
New recommendations — for males — include routine use of HPV4 at ages 11 or 12 years and vaccination through age 26 for those who have not completed the three-dose series.
SUMMARY AND COMMENT
Rhinoviruses Cause Severe Disease in Very Low Birth Weight Infants
- January 11, 2012
- Robert S. Baltimore, MD
- Infectious Diseases
Among premature infants in Buenos Aires, rhinoviruses were the most common cause of all acute respiratory infections, of bronchiolitis, and of hospitalization for such illnesses.
- Reviewing:
- Miller EK et al. Pediatrics 2012 Jan 1; 129:e60
