GERD / Peptic Ulcers
The latest information on GERD and peptic ulcers — summaries and comments on acid reflux, esophagitis, H. pylori, proton-pump inhibitors, and more — drawn from across our specialties. Sign up now for monthly e-mail alerts on new content.
SUMMARY AND COMMENT
Trends in Uncomplicated Peptic Ulcer Disease
- November 6, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Incidence in the U.K. declined by 50% during the last decade.
- Reviewing:
- Cai S et al. Aliment Pharmacol Ther 2009 Nov; 30:1039
SUMMARY AND COMMENT
H. pylori and Gastric Cancer
- October 30, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Eradication of H. pylori infection did not significantly reduce the incidence of gastric cancer.
- Reviewing:
- Mabe K et al. World J Gastroenterol 2009 Sep 14; 15:4290
SUMMARY AND COMMENT
PPIs and Clopidogrel: Data Trumps Fear
- October 16, 2009
- David A. Johnson, MD
- Gastroenterology
Antiplatelet function was diminished in PPI users, but cardiovascular outcomes were similar in PPI users and nonusers.
- Reviewing:
- O'Donoghue ML et al. Lancet 2009 Sep 19; 374:989
SUMMARY AND COMMENT
Does Coagulation Status Predict Band-Ulcer Bleeding After Band Ligation?
- October 16, 2009
- Atif Zaman, MD, MPH
- Gastroenterology
Neither standard nor expanded coagulation indices were predictive.
- Reviewing:
- Vieira da Rocha EC et al. Clin Gastroenterol Hepatol 2009 Sep; 7:988
SUMMARY AND COMMENT
Early Endoscopy for Older Patients with Bleeding Peptic Ulcers
- October 16, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Compared with delayed endoscopies, early procedures were associated with shorter hospital stays and lower rates of surgery.
- Reviewing:
- Cooper GS et al. Gastrointest Endosc 2009 Aug; 70:229
SUMMARY AND COMMENT
Endoscopy for Evaluation of Dyspepsia
- October 9, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Endoscopy detected few malignant lesions but still might merit the cost in patients aged 50 or older.
- Reviewing:
- Vakil N et al. Clin Gastroenterol Hepatol 2009 Jul; 7:756
SUMMARY AND COMMENT
Trends in Upper Gastrointestinal Bleeding
- October 2, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
During a 25-year period at an Italian hospital, the incidence of upper GI bleeding declined, as did associated mortality.
- Reviewing:
- Loperfido S et al. Gastrointest Endosc 2009 Aug; 70:212
SUMMARY AND COMMENT
Peptic-Ulcer Bleeding: Trends in Sweden
- September 18, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Incidence of duodenal and gastric ulcers has declined.
- Reviewing:
- Sadic J et al. Aliment Pharmacol Ther 2009 Aug 15; 30:392
SUMMARY AND COMMENT
Barrett Esophagus in Patients with Erosive Esophagitis
- September 18, 2009
- David A. Johnson, MD
- Gastroenterology
Approximately 9% of patients with EE had BE diagnosed during subsequent upper endoscopy.
- Reviewing:
- Modiano N and Gerson LB. Gastrointest Endosc 2009 May; 69:1014
SUMMARY AND COMMENT
Is Standard Ulcer Therapy Effective in Patients with Uremia?
- September 11, 2009
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
A small study did not show benefit beyond 7 days.
- Reviewing:
- Tseng G-Y et al. Aliment Pharmacol Ther 2009 Aug; 30:406
