GERD / Peptic Ulcers
The latest information on GERD and peptic ulcers — summaries and comments on acid reflux, esophagitis, H. pylori, proton-pump inhibitors, and more — drawn from across our specialties. Sign up now for monthly e-mail alerts on new content.
SUMMARY AND COMMENT
Bleeding Peptic Ulcers and End-Stage Renal Disease
- February 5, 2010
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Among patients with bleeding ulcers, those with ESRD had higher risk for rebleeding than did those with chronic kidney disease or normal renal function.
- Reviewing:
- Cheung J et al. Gastrointest Endosc 2010 Jan; 71:44
SUMMARY AND COMMENT
Which Treatment Is Better for GERD?Free
- January 29, 2010
- David A. Johnson, MD
- Gastroenterology
Compared with medical therapy, surgery was associated with higher rates of continuous remission, but the results are questionable.
- Reviewing:
- Lundell L et al. Clin Gastroenterol Hepatol 2009 Dec; 7:1292
SUMMARY AND COMMENT
Barrett Esophagus and Neoplasia
- January 29, 2010
- David A. Johnson, MD
- Gastroenterology
Use of proton-pump inhibitors was associated with diminished risk for high-grade dysplasia or esophageal adenocarcinoma.
- Reviewing:
- Nguyen DM et al. Clin Gastroenterol Hepatol 2009 Dec; 7:1299
SUMMARY AND COMMENT
Low-Dose Aspirin Therapy After Peptic Ulcer Bleeding
- January 29, 2010
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Mortality risk was diminished in patients receiving low-dose aspirin for vascular disease.
- Reviewing:
- Sung JJY et al. Ann Intern Med 2010 Jan 5; 152:1
SUMMARY AND COMMENT
A New Rapid Urease Test for H. pylori
- January 29, 2010
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Test sensitivity at 5 minutes was 94.5%.
- Reviewing:
- Vaira D et al. Aliment Pharmacol Ther 2010 Jan 15; 31:331
SUMMARY AND COMMENT
Proton-Pump Inhibitors and Fundic Gland Polyps
- January 22, 2010
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
Use of PPIs for >48 months was an independent predictor of FGPs.
- Reviewing:
- Ally MR et al. Dig Dis Sci 2009 Dec; 54:2617
SUMMARY AND COMMENT
SSRIs and Upper Gastrointestinal Bleeding
- January 15, 2010
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
A new case-control study confirms that use of selective serotonin reuptake inhibitors increases risk for bleeding, but questions remain.
- Reviewing:
- Dall M et al. Clin Gastroenterol Hepatol 2009 Dec; 7:1314
SUMMARY AND COMMENT
Do Proton-Pump Inhibitors Decrease Bone-Mineral Density?
- January 8, 2010
- David A. Johnson, MD
- Gastroenterology
PPI use was not associated with osteoporosis or accelerated bone-mineral density loss. CME
- Reviewing:
- Targownik LE et al. Gastroenterology 2009 Nov 18
SUMMARY AND COMMENT
Is It Okay for Patients with Peptic Ulcer Bleeding to Continue Low-Dose Aspirin?
- December 23, 2009
- Joel M. Gore, MD
- Cardiology
For patients at cardiovascular risk, the short-term survival advantage of continuing aspirin therapy outweighed the bleeding risk.
- Reviewing:
- Sung JJY et al. Ann Intern Med 2009 Dec 1
SUMMARY AND COMMENT
Reflux Esophagitis: A Novel Theory
- December 18, 2009
- David A. Johnson, MD
- Gastroenterology
Gastric refluxate might not damage the esophagus directly but rather stimulate secretion of cytokines that mediate esophageal injury.
- Reviewing:
- Souza RF et al. Gastroenterology 2009 Nov; 137:1776
