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GERD / Peptic Ulcers

The latest information on GERD and peptic ulcers — summaries and comments on acid reflux, esophagitis, H. pylori, proton-pump inhibitors, and more — drawn from across our specialties. Sign up now for monthly e-mail alerts on new content.

SUMMARY AND COMMENT

A Murky Relationship Between GERD and Interstitial Lung Disease

Previous studies document a high prevalence of GERD in patients with idiopathic pulmonary fibrosis but provide no evidence of causality.

SUMMARY AND COMMENT

PPIs Don't Ease Asthma Symptoms in Children with Severe Asthma and Asymptomatic GERD

In addition, lansoprazole raised the incidence of adverse events.

SUMMARY AND COMMENT

PPIs and CAP, Revisited

In a retrospective, nested case-control study, the risk for community-acquired pneumonia was 29% higher with current use of a proton-pump inhibitor than with past use.

SUMMARY AND COMMENT

A New Four-Drug Regimen for H. pylori Infection?

Eradication was better than with standard triple therapy.

SUMMARY AND COMMENT

Sequential Therapy Bests Triple Therapy for H. pylori Infection

Eradication rates were higher; adverse events were similar.

SUMMARY AND COMMENT

Diagnosing Gastroenterological Causes of Noncardiac Chest PainFree

Endoscopy and pH tests should be used to confirm GERD status to guide decisions on treatment with PPIs and the need for further diagnostic testing. CME

SUMMARY AND COMMENT

A New Way to Assess Risk in Upper Gastrointestinal Bleeding?

An assessment of five readily available measures in emergency settings could improve patient triage and outcomes. CME

SUMMARY AND COMMENT

Gastrointestinal Bleeding with Low-Dose Aspirin

A meta-analysis supports evidence of increased risk for GI bleeding from low-dose aspirin alone and in combination with clopidogrel or anticoagulants.

SUMMARY AND COMMENT

Can Celecoxib or Helicobacter pylori Eradication Reduce Gastric Lesions?

Regression of precancerous lesions was better with either treatment than with placebo.

SUMMARY AND COMMENT

Predictors of Rebleeding After Endoscopic Therapy for Peptic Ulcers

Risk factors were hemodynamic instability, a low hemoglobin value, active bleeding, large ulcer size, and an ulcer in the posterior duodenum or high on the lesser gastric curve. CME

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