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Oncology and Hematology Editor's Picks

SUMMARY AND COMMENT

A New Factor Xa Inhibitor Prepares for Its Close-Up

Otamixaban shows promise in patients with ACS, but do we really need another intravenous anticoagulant?

SUMMARY AND COMMENT

Mastectomy Rates Are RisingFree

And breast-conserving surgery rates are falling — Can preoperative MRI be responsible? Interview

SUMMARY AND COMMENT

Is Clinical Breast Examination, Added to Mammography, Worthwhile?

CBE was associated with 55 additional false-positives for each additional breast cancer detected.

SUMMARY AND COMMENT

Polymorphisms in CTLA4 Confer Susceptibility to Nonmelanoma Skin CancersFree

A genetic variant that confers excess risk for autoimmune disease may also protect against nonmelanoma skin cancers.

SUMMARY AND COMMENT

Warfarin for Stroke Prevention in Patients with Atrial Fibrillation

Results of a large observational study provide current data for accurate risk-benefit estimation. CME

SUMMARY AND COMMENT

Overdiagnosis in PSA Screening

An analysis suggests that many men have been treated unnecessarily because of PSA screening.

SUMMARY AND COMMENT

An Alternative to Warfarin in Patients with Atrial Fibrillation?

Compared with warfarin, low-dose dabigatran performed better with regard to safety but not efficacy, and high-dose dabigatran performed better with regard to efficacy but not safety.

SUMMARY AND COMMENT

Refining Antiplatelet Treatment in Patients with Acute Coronary Syndromes

In a randomized trial, oral ticagrelor outperformed clopidogrel.

SUMMARY AND COMMENT

Photodynamic Therapy and the Immune System

PDT apparently increases antitumor immunity in addition to directly destroying lesions of basal cell carcinoma.

SUMMARY AND COMMENT

Ovarian Status and Risk for Lung Cancer

Further evidence that functional ovaries protect against lung cancer

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