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Oncology and Hematology Editor's Picks
Screening for Lung Cancer: Radiography? No. Low-Dose CT? Maybe.
- December 29, 2011
- Thomas L. Schwenk, MD
- General Medicine
Low-dose computed tomography was a more effective screening tool than chest radiography, but its high sensitivity came with low specificity.
SUMMARY AND COMMENT
No Evidence of Adverse Outcomes from Long-Term Statin Therapy
- December 20, 2011
- Bruce Soloway, MD
- General Medicine
Vascular benefits persist, without elevated risk for nonvascular morbidity or cancer.
- Reviewing:
- Heart Protection Study Collaborative Group. Lancet 2011 Dec 10; 378:2013
SUMMARY AND COMMENT
Sexual Activity After Menopause
- December 15, 2011
- Anne A. Moore, WHNP/ANP-BC, FAANP
- Women's Health
Most WHI participants reported being satisfied with their sexual activity.
- Reviewing:
- Gass MLS et al. Menopause 2001 Nov; 18:1160
SUMMARY AND COMMENT
Do Squamous Cell Carcinomas Develop More Rapidly in Patients Treated with Etanercept?
- December 16, 2011
- Jeffrey P. Callen, MD
- Dermatology
Watch for nonmelanoma skin cancer in patients with previous UV therapy who are receiving biologic therapy.
- Reviewing:
- Brewer JD et al. Int J Dermatol 2011 Dec; 50:1555
SUMMARY AND COMMENT
Prothrombin Complex Concentrate Reverses the Effects of Rivaroxaban but Not Dabigatran
- December 14, 2011
- Mark S. Link, MD
- Cardiology
In healthy volunteers, coagulation test results rapidly normalized with a PCC after factor Xa — but not direct thrombin — inhibition.
- Reviewing:
- Eerenberg ES et al. Circulation 2011 Oct 4; 124:1573
SUMMARY AND COMMENT
Aspirin 600 mg Daily Reduced Cancers in Lynch Syndrome
- December 2, 2011
- Douglas K. Rex, MD
- Gastroenterology
Patients randomized to aspirin for 2 years had about half the risk for colorectal cancer as a placebo group.
- Reviewing:
- Burn J et al. Lancet 2011 Oct 28
Preoperative Anemia Is a Prognostic Factor for Poor Outcomes After Noncardiac Surgery
- November 28, 2011
- Aaron J. Calderon, MD, FACP
- Hospital Medicine
Even mild anemia is associated with higher perioperative morbidity and mortality, but should we change our practice?
- Reviewing:
- Musallam KM et al. Lancet 2011 Oct 15; 378:1396
SUMMARY AND COMMENT
Detection Rates Are Similar for Digital and Film MammographyFree
- November 17, 2011
- Jamaluddin Moloo, MD, MPH
- General Medicine
Digital mammography had better sensitivity when breast tissue was dense.
- Reviewing:
- Kerlikowske K et al. Ann Intern Med 2011 Oct 18; 155:493
SUMMARY AND COMMENT
Solid Organ Transplant Recipients Have Doubled Risk for Cancer
- November 17, 2011
- Thomas L. Schwenk, MD
- General Medicine
Lymphoma and lung cancer were most common.
- Reviewing:
- Engels EA et al. JAMA 2011 Nov 2; 306:1891
SUMMARY AND COMMENT
Clopidogrel Dosing Based on Genotype: What Difference Does It Make?
- November 16, 2011
- Joel M. Gore, MD
- Cardiology
In patients heterozygous for the CYP2C19*2 allele, higher doses significantly reduced platelet reactivity, but whether genotype-guided dosing improves outcomes remains unknown.
- Reviewing:
- Mega JL et al. JAMA 2011 Nov 23/30; 306:2221
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