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HIV/AIDS Editor's Picks
SUMMARY AND COMMENT
Testing Midstream Urine for Chlamydia trachomatis
- February 2, 2012
- Anna Wald, MD, MPH
- Women's Health
Midstream samples might be adequate for evaluating both chlamydial and urinary tract infections, but study results were not definitive.
- Reviewing:
- Mangin D et al. Ann Fam Med 2012 Jan/Feb; 10:50
SUMMARY AND COMMENT
High-Dose Antivirals Do Not Fully Suppress Reactivation of Genital Herpes Simplex
- January 31, 2012
- Bruce Soloway, MD
- General Medicine
Suppressive therapy is not adequate for preventing transmission.
- Reviewing:
- Johnston C et al. Lancet 2012 Jan 5
SUMMARY AND COMMENT
New Antivirals Show Promise for an Interferon-Free Hepatitis C Treatment
- January 18, 2012
- Atif Zaman, MD, MPH
- Gastroenterology
Patients with HCV genotype 1 and previous null response achieved a 36% sustained virologic response at 24 weeks of therapy with daclatasvir and asunaprevir alone.
- Reviewing:
- Lok AS et al. N Engl J Med 2012 Jan 19; 366:216
SUMMARY AND COMMENT
Effective Short-Course Treatment for Latent Tuberculosis
- December 20, 2011
- Abigail Zuger, MD
- General Medicine
Three months of isoniazid plus rifapentine worked as well as 9 months of isoniazid.
- Reviewing:
- Sterling TR et al. N Engl J Med 2011 Dec 8; 365:2155
CLINICAL PRACTICE GUIDELINE WATCH
Recommendations for Use of Short-Course Isoniazid-Rifapentine for Latent TBFree
- December 21, 2011
- Stephen G. Baum, MD
- Infectious Diseases
This two-drug regimen, administered weekly for just 12 weeks, is efficacious in preventing active disease in patients with latent Mycobacterium tuberculosis infection.
- Reviewing:
- Centers for Disease Control and Prevention (CDC). MMWR Morb Mortal Wkly Rep 2011 Dec 9; 60:1650
SUMMARY AND COMMENT
Low Vitamin D Levels Linked to Active TuberculosisFree
- November 30, 2011
- Richard T. Ellison III, MD
- Infectious Diseases
Seasonal declines in mean vitamin D levels were followed by seasonal increases in TB notifications.
- Reviewing:
- Martineau AR et al. Proc Natl Acad Sci U S A 2011 Nov 22; 108:19013
SUMMARY AND COMMENT
Quantitative PCR for Differentiating Between Pneumocystis Colonization and Infection
- November 16, 2011
- Thomas Glück, MD
- Infectious Diseases
A newly developed strategy allowed definitive characterization of 96% of the samples evaluated.
- Reviewing:
- Alanio A et al. Clin Microbiol Infect 2011 Oct; 17:1531
SUMMARY AND COMMENT
HPV Vaccine Beneficial in Men Who Have Sex with MenFree
- October 26, 2011
- Larry M. Baddour, MD
- Infectious Diseases
A quadrivalent HPV vaccine significantly reduced the rate of anal intraepithelial neoplasia in this high-risk population. Interview
- Reviewing:
- Palefsky JM et al. N Engl J Med 2011 Oct 27; 365:1576
SUMMARY AND COMMENT
Should We Continue Entecavir for HBV Infection Despite Partial Virologic Response?
- October 14, 2011
- Atif Zaman, MD, MPH
- Gastroenterology
Results from a prospective cohort study found continued virologic response without viral resistance to entecavir despite PVR for up to 3 years. CME
- Reviewing:
- Zoutendijk R et al. Hepatology 2011 Aug; 54:443
SUMMARY AND COMMENT
RTS,S/AS01 Vaccine Reduces Malaria Incidence by HalfFree
- October 20, 2011
- Mary E. Wilson, MD
- Infectious Diseases
Initial results from a phase III trial show protection against clinical and severe malaria during the 12 months after vaccination in children aged 5 to 17 months.
- Reviewing:
- The RTS,S Clinical Trials Partnership. N Engl J Med 2011 Oct 18
