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General Medicine Editor's Picks

SUMMARY AND COMMENT

Lifetime Cardiovascular Risk: The More Things Change . . .

Risk factors are less prevalent than in the past, but they are just as predictive of outcome.

Preventing Readmissions: Should We Be Looking at the Hospital Exit or the Entrance?

Regional admission rates for congestive heart failure and pneumonia explain much of the variation in hospital readmission rates.

SUMMARY AND COMMENT

PPIs and CAP, Revisited

In a retrospective, nested case-control study, the risk for community-acquired pneumonia was 29% higher with current use of a proton-pump inhibitor than with past use.

SUMMARY AND COMMENT

Antidepressants and Fetal Risk: A New Look at SSRIs During PregnancyFree

Maternal use of selective serotonin reuptake inhibitors during late pregnancy raised risk for neonatal pulmonary hypertension, but individual risk-benefit profiles should be evaluated.

SUMMARY AND COMMENT

Is Acetaminophen a Culprit in Asthma?Free

Positive associations exist between acetaminophen use and asthma in children.

SUMMARY AND COMMENT

Androgen-Deprivation Therapy and Cardiovascular Mortality

A meta-analysis indicates that ADT does not affect CV mortality and is associated with reduced disease-specific and all-cause mortality in patients with nonmetastatic prostate cancer.

SUMMARY AND COMMENT

Is Nasogastric Lavage Beneficial for Acute Gastrointestinal Bleeding?Free

The procedure increased the likelihood of early endoscopy but not better patient outcomes, such as lower mortality. The question merits prospective analysis.

SUMMARY AND COMMENT

Does Anti–Tumor Necrosis Factor α Therapy Increase the Risk for Serious Infection?

In this large cohort study, unlike in most of the previous studies, researchers found no increased risk for serious infections with TNF antagonists.

SUMMARY AND COMMENT

Emerging Treatment Options for Severe Acute Alcoholic Hepatitis

Adding N-acetylcysteine to glucocorticoid therapy did not improve 6-month survival. Early liver transplant did, but in a selectively chosen subgroup. CME

SUMMARY AND COMMENT

Patients with Diabetes and Prior Stroke Benefit from Thrombolytic Therapy for Treatment of Acute StrokeFree

This finding will expand eligibility for thrombolysis in the U.S.

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