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Gastroenterology Editor's Picks
Selective and Nonselective NSAIDs Are Associated with Excess Cardiovascular Risk
- December 29, 2011
- Anthony L. Komaroff, MD
- General Medicine
These drugs were risky in myocardial infarction patients and were associated with new-onset atrial fibrillation.
SUMMARY AND COMMENT
Genotype Testing for Clopidogrel Responsiveness May Not Predict Events
- January 4, 2012
- Howard C. Herrmann, MD
- Cardiology
A meta-analysis finds no association between CYP2C19 genotype and cardiovascular outcomes in clopidogrel recipients, but concerns about stent thrombosis linger.
- Reviewing:
- Holmes MV et al. JAMA 2011 Dec 28; 306:2704
SUMMARY AND COMMENT
Does Anti–Tumor Necrosis Factor α Therapy Increase the Risk for Serious Infection?
- November 10, 2011
- Jeffrey P. Callen, MD
- Dermatology
In this large cohort study, unlike in most of the previous studies, researchers found no increased risk for serious infections with TNF antagonists.
- Reviewing:
- Grijalva CG et al. JAMA 2011 Nov 6
SUMMARY AND COMMENT
Antiplatelet Therapy for Atrial Fibrillation: One Drug or Two?
- December 7, 2011
- Joel M. Gore, MD
- Cardiology
In an ACTIVE substudy, the net clinical benefit of adding clopidogrel to aspirin in patients who were not candidates for warfarin was small and statistically nonsignificant.
- Reviewing:
- Connolly SJ et al. Ann Intern Med 2011 Nov 1; 155:579
SUMMARY AND COMMENT
When Is Dabigatran More Cost-Effective Than Warfarin?
- December 7, 2011
- Mark S. Link, MD
- Cardiology
For patients with nonvalvular atrial fibrillation who are not well-controlled on warfarin, the 150-mg dose of dabigatran can be a cost-effective choice for stroke prevention.
- Reviewing:
- Pink J et al. BMJ 2011 Oct 31; 343:d6333
SUMMARY AND COMMENT
RTS,S/AS01 Vaccine Reduces Malaria Incidence by HalfFree
- October 20, 2011
- Mary E. Wilson, MD
- Infectious Diseases
Initial results from a phase III trial show protection against clinical and severe malaria during the 12 months after vaccination in children aged 5 to 17 months.
- Reviewing:
- The RTS,S Clinical Trials Partnership. N Engl J Med 2011 Oct 18
SUMMARY AND COMMENT
Bariatric Surgery: Gastric Bypass vs. Duodenal Switch
- October 11, 2011
- Jamaluddin Moloo, MD, MPH
- General Medicine
Duodenal switch patients lost more weight but experienced more adverse effects.
- Reviewing:
- Søvik TT et al. Ann Intern Med 2011 Sep 6; 155:281
SUMMARY AND COMMENT
MRI Studies Can Be Performed Safely in Patients with Implantable Cardiac Devices
- October 25, 2011
- Paul S. Mueller, MD, MPH, FACP
- General Medicine
Patients were monitored carefully during magnetic resonance imaging procedures and had no apparent problems. Interview
- Reviewing:
- Nazarian S et al. Ann Intern Med 2011 Oct 4; 155:415
SUMMARY AND COMMENT
Phone-Based CBT Is Effective in Easing Chronic Widespread Pain
- December 1, 2011
- Thomas L. Schwenk, MD
- General Medicine
Exercise was roughly equally as effective as cognitive-behavioral therapy, and both together were even better.
- Reviewing:
- McBeth J et al. Arch Intern Med 2011 Nov 14
SUMMARY AND COMMENT
Short-Term Stroke Risk in Patients Who Suffer Transient Ischemic Attacks
- October 27, 2011
- Allan S. Brett, MD
- General Medicine
Combining magnetic resonance imaging and ABCD2 scoring improves stroke prediction.
- Reviewing:
- Giles MF et al. Neurology 2011 Sep 27; 77:1222
