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Depression / Anxiety

The latest information on antidepressants, anxiety disorders, bipolar disorder, psychotherapy, and more, drawn from across our primary care and specialty care areas. Sign up now for monthly e-mail alerts on new content.

SUMMARY AND COMMENT

Debunking the Serotonin Gene–Life Stress Hypothesis?

A meta-analysis finds little evidence that gene–environment interaction increases risk for depression.

SUMMARY AND COMMENT

The FDA’s SSRI Warning: "We’re from the Government, and We’re Here to Help"?

The FDA’s black-box warning about juvenile suicidality and SSRIs might have had unintended consequences: Prescription rates and depression diagnoses, including in adults, have decreased significantly.

SUMMARY AND COMMENT

Early Predictors of Response to Atomoxetine

A 25% reduction in core ADHD symptoms by 4 weeks of treatment predicted a good response at 6 to 8 weeks.

SUMMARY AND COMMENT

Doubts About Genetic Determinants of Depression Risk

No association was noted between risk for depression and the interaction between genotype and stressful life events.

SUMMARY AND COMMENT

Citalopram Ineffective for Children with Autism Spectrum DisordersFree

Repetitive behaviors did not improve with treatment, and activating behaviors increased.

SUMMARY AND COMMENT

Adding ADHD to Bipolar Disorder in Adults: A Volatile Mixture

Even if it disappears in adulthood, ADHD in childhood suggests a more difficult course of bipolar disorder.

SUMMARY AND COMMENT

The Environment and Depressive Symptoms in Older Adults

Neighborhood characteristics may contribute to risk for depressive symptoms.

SUMMARY AND COMMENT

Inhibit Histone Deacetylase Type 2 to Improve Memory?

Results from an animal study might indicate a new research avenue.

SUMMARY AND COMMENT

Preventing Depression in At-Risk Youth

Cognitive-behavioral therapy reduced incident depressive episodes, but only in adolescents whose parents were not depressed at baseline.

SUMMARY AND COMMENT

Preventing Depression in Adolescents

Cognitive-behavioral therapy lowered depression risk in teens, if their parents were not actively depressed.

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