Depression / Anxiety
The latest information on antidepressants, anxiety disorders, bipolar disorder, psychotherapy, and more, drawn from across our primary care and specialty care areas. Sign up now for monthly e-mail alerts on new content.
SUMMARY AND COMMENT
More on Polypharmacy for Psychiatric Patients
- February 8, 2010
- Steven Dubovsky, MD
- Psychiatry
Researchers examine epidemiologic data on trends in prescribing multiple medications.
- Reviewing:
- Mojtabai R and Olfson M. Arch Gen Psychiatry 2010 Jan; 67:26
SUMMARY AND COMMENT
New Directions in Psychosurgery
- February 8, 2010
- Steven Dubovsky, MD
- Psychiatry
Epidural cortical stimulation of prefrontal regions and DBS focusing on the nucleus accumbens show promising, if preliminary, effects in patients with highly treatment-resistant depression.
- Reviewing:
- Bewernick BH et al. Biol Psychiatry 2010 Jan 15; 67:110
SUMMARY AND COMMENT
Depression Level and Suitability of Drug Treatment
- February 1, 2010
- Peter Roy-Byrne, MD
- Psychiatry
Antidepressants are best reserved for patients with more-severe depression — but what alternatives are accessible to patients with mild or moderate disease?
- Reviewing:
- Fournier JC et al. JAMA 2010 Jan 6; 303:47
SUMMARY AND COMMENT
The Porous Border Between Bipolar and Unipolar Mood Disorders
- February 1, 2010
- Steven Dubovsky, MD
- Psychiatry
The supposed dichotomy might instead be a continuum, according to this community-based study.
- Reviewing:
- Zimmermann P et al. Arch Gen Psychiatry 2009 Dec; 66:1341
SUMMARY AND COMMENT
Knitting Up the Raveled Sleeve of Care
- February 1, 2010
- Deborah Cowley, MD
- Psychiatry
Earlier parent-set bedtimes are associated with less depression and suicidal ideation in adolescents.
- Reviewing:
- Gangwisch JE et al. Sleep 2010 Jan; 33:97
SUMMARY AND COMMENT
Substance Use Disorders and the Course of Bipolar Disorder
- January 25, 2010
- Joel Yager, MD
- Psychiatry
Comorbid substance use disorder increases the risk that a depressive episode will switch to mania or hypomania, but may have few effects on recovery.
- Reviewing:
- Ostacher MJ et al. Am J Psychiatry 2009 Dec 15
SUMMARY AND COMMENT
Delivering Medical Care to Public Mental Health Patients
- January 25, 2010
- Joel Yager, MD
- Psychiatry
Medical case management in community mental health centers improves access and outcomes.
- Reviewing:
- Druss BG et al. Am J Psychiatry 2009 Dec 15
SUMMARY AND COMMENT
Antidepressant Use and Cardiovascular Risk in Postmenopausal Women
- January 21, 2010
- Diane E. Judge, APN/CNP
- Women's Health
Although antidepressants were not associated with coronary heart disease risk, SSRIs were associated with higher stroke risk and both SSRIs and TCAs with higher all-cause mortality.
- Reviewing:
- Smoller JW et al. Arch Intern Med 2009 Dec 14/28; 169:2128
SUMMARY AND COMMENT
SSRIs and Upper Gastrointestinal Bleeding
- January 15, 2010
- David J. Bjorkman, MD, MSPH (HSA), SM (Epid.)
- Gastroenterology
A new case-control study confirms that use of selective serotonin reuptake inhibitors increases risk for bleeding, but questions remain.
- Reviewing:
- Dall M et al. Clin Gastroenterol Hepatol 2009 Dec; 7:1314
SUMMARY AND COMMENT
Morphine and PTSD Risk in Injured Combat VeteransFree
- January 13, 2010
- Peter Roy-Byrne, MD
- Psychiatry
Early use of morphine seems to protect against the later development of the disorder. CME
- Reviewing:
- Holbrook TL et al. N Engl J Med 2010 Jan 14; 362:110
