Depression / Anxiety
The latest information on antidepressants, anxiety disorders, bipolar disorder, psychotherapy, and more, drawn from across our primary care and specialty care areas. Sign up now for monthly e-mail alerts on new content.
SUMMARY AND COMMENT
Quetiapine Beats Lithium and Paroxetine for Bipolar DepressionFree
- March 8, 2010
- Peter Roy-Byrne, MD
- Psychiatry
Two manufacturer-sponsored studies show efficacy for this antipsychotic as acute treatment, but careful clinical judgment remains necessary when prescribing to individual patients.
- Reviewing:
- Young AH et al. J Clin Psychiatry 2010 Feb; 71:150
SUMMARY AND COMMENT
More on Depression and Diabetes
- March 8, 2010
- Joel Yager, MD
- Psychiatry
Even low-grade preexisting depression may increase the risk for diabetes.
- Reviewing:
- Campayo A et al. Am J Psychiatry 2010 Feb 1
SUMMARY AND COMMENT
Does a Sick Cingulate Syndrome Promote Anxiety?
- March 8, 2010
- Joel Yager, MD
- Psychiatry
In generalized anxiety disorder, the pregenual anterior cingulate might inadequately regulate emotional processing by the amygdala.
- Reviewing:
- Etkin A et al. Am J Psychiatry 2010 Feb 1
SUMMARY AND COMMENT
Do Selective Serotonin Reuptake Inhibitors Attenuate Tamoxifen's Benefits in Breast Cancer Survivors?
- March 4, 2010
- Andrew M. Kaunitz, MD
- Women's Health
Paroxetine was associated with excess mortality in breast cancer survivors who were receiving tamoxifen as adjuvant therapy.
- Reviewing:
- Kelly CM et al. BMJ 2010 Feb 8; 340:c693
SUMMARY AND COMMENT
Intimate Relationship Problems and Depression Treatment Outcome
- March 1, 2010
- Deborah Cowley, MD
- Psychiatry
Chronically depressed patients are less likely to remit in the presence of dyadic discord.
- Reviewing:
- Denton WH et al. Psychol Med 2010 Mar; 40:415
SUMMARY AND COMMENT
A New Dimension of Panic Anxiety
- February 22, 2010
- Steven Dubovsky, MD
- Psychiatry
Studies in rats and people identify the role played by excessive activity of orexin.
- Reviewing:
- Johnson PL et al. Nat Med 2010 Jan; 16:111
SUMMARY AND COMMENT
Don't Forget to Use Them After Stroke
- February 22, 2010
- Jonathan Silver, MD
- Psychiatry
An antidepressant improves memory in nondepressed poststroke patients.
- Reviewing:
- Jorge RE et al. Arch Gen Psychiatry 2010 Feb; 67:187
SUMMARY AND COMMENT
Venlafaxine Doesn't Confer Excess Risk for Sudden Cardiac Death
- February 18, 2010
- Paul S. Mueller, MD
- General Medicine
Mortality among depressed patients was not associated with a particular antidepressant.
- Reviewing:
- Martinez C et al. BMJ 2010 Feb 5; 340:c249
SUMMARY AND COMMENT
Paroxetine Use Negates Benefits of Tamoxifen in Women with Breast Cancer
- February 18, 2010
- Paul S. Mueller, MD
- General Medicine
Paroxetine inhibits conversion of tamoxifen to its active metabolite.
- Reviewing:
- Kelly CM et al. BMJ 2010 Feb 8; 340:c693
SUMMARY AND COMMENT
Sudden Infant Death and Parental Psychopathology
- February 12, 2010
- Barbara Geller, MD
- Psychiatry
Hospitalization of a parent is associated with elevated risk for SIDS in this study from Sweden.
- Reviewing:
- Webb RT et al. Arch Gen Psychiatry 2010 Jan; 67:69
