Depression / Anxiety
The latest information on antidepressants, anxiety disorders, bipolar disorder, psychotherapy, and more, drawn from across our primary care and specialty care areas. Sign up now for monthly e-mail alerts on new content.
SUMMARY AND COMMENT
Debunking the Serotonin Gene–Life Stress Hypothesis?
- June 29, 2009
- Peter Roy-Byrne, MD
- Psychiatry
A meta-analysis finds little evidence that gene–environment interaction increases risk for depression.
- Reviewing:
- Risch N et al. JAMA 2009 Jun 17; 301:2462
SUMMARY AND COMMENT
The FDA’s SSRI Warning: "We’re from the Government, and We’re Here to Help"?
- June 29, 2009
- Steven Dubovsky, MD
- Psychiatry
The FDA’s black-box warning about juvenile suicidality and SSRIs might have had unintended consequences: Prescription rates and depression diagnoses, including in adults, have decreased significantly.
- Reviewing:
- Libby AM et al. Arch Gen Psychiatry 2009 Jun; 66:633
SUMMARY AND COMMENT
Early Predictors of Response to Atomoxetine
- June 24, 2009
- Martin T. Stein, MD
- Pediatrics and Adolescent Medicine
A 25% reduction in core ADHD symptoms by 4 weeks of treatment predicted a good response at 6 to 8 weeks.
- Reviewing:
- Newcorn JH et al. J Am Acad Child Adolesc Psychiatry 2009 May; 48:511
SUMMARY AND COMMENT
Doubts About Genetic Determinants of Depression Risk
- June 23, 2009
- Thomas L. Schwenk, MD
- General Medicine
No association was noted between risk for depression and the interaction between genotype and stressful life events.
- Reviewing:
- Risch N et al. JAMA 2009 Jun 17; 301:2462
SUMMARY AND COMMENT
Citalopram Ineffective for Children with Autism Spectrum DisordersFree
- June 22, 2009
- Barbara Geller, MD
- Psychiatry
Repetitive behaviors did not improve with treatment, and activating behaviors increased.
- Reviewing:
- King BH et al. Arch Gen Psychiatry 2009 Jun; 66:583
SUMMARY AND COMMENT
Adding ADHD to Bipolar Disorder in Adults: A Volatile Mixture
- June 22, 2009
- Joel Yager, MD
- Psychiatry
Even if it disappears in adulthood, ADHD in childhood suggests a more difficult course of bipolar disorder.
- Reviewing:
- Rydén E et al. Acta Psychiatr Scand 2009 May 7
SUMMARY AND COMMENT
The Environment and Depressive Symptoms in Older Adults
- June 22, 2009
- Joel Yager, MD
- Psychiatry
Neighborhood characteristics may contribute to risk for depressive symptoms.
- Reviewing:
- Beard JR et al. Am J Public Health 2009 Jul; 99:1308
SUMMARY AND COMMENT
Inhibit Histone Deacetylase Type 2 to Improve Memory?
- June 22, 2009
- Barbara Geller, MD
- Psychiatry
Results from an animal study might indicate a new research avenue.
- Reviewing:
- Guan J-S et al. Nature 2009 May 7; 459:55
SUMMARY AND COMMENT
Preventing Depression in At-Risk Youth
- June 17, 2009
- Alain Joffe, MD, MPH, FAAP
- Pediatrics and Adolescent Medicine
Cognitive-behavioral therapy reduced incident depressive episodes, but only in adolescents whose parents were not depressed at baseline.
- Reviewing:
- Garber J et al. JAMA 2009 Jun 3; 301:2215
SUMMARY AND COMMENT
Preventing Depression in Adolescents
- June 16, 2009
- Thomas L. Schwenk, MD
- General Medicine
Cognitive-behavioral therapy lowered depression risk in teens, if their parents were not actively depressed.
- Reviewing:
- Garber J et al. JAMA 2009 Jun 3; 301:2215
