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Bone and Joint Disease

The latest information on arthritis, bisphosphonates, osteoporosis, joint pain, and more, drawn from across our primary care and specialty care areas. Sign up now for monthly e-mail alerts on new content.

Thiazolidinediones and Risk for Fractures

In an observational study, users of TZDs had higher risk for fractures than those taking other antidiabetes medications.

Alendronate and Risk for Atrial Fibrillation

Because of inconsistent results across several studies, it's still unclear whether oral bisphosphonates increase risk for atrial fibrillation.

Be Still My Heart — Bisphosphonates Not Linked to Arrhythmias

Use of oral bisphosphonates did not increase risk for atrial fibrillation and flutter.

Should We Be Concerned About Jaw Osteonecrosis with Oral Bisphosphonates?

BRONJ probably occurs rarely with oral bisphosphonate therapy, but the true incidence isn’t clear yet.

A New Approach to Osteoporosis and Fracture Risk

A new statistical model predicts 10-year risk for hip and other major fractures.

Oral Bisphosphonates Do Not Increase Risk for Atrial Fibrillation and Flutter

A previous finding of increased risk for atrial fibrillation and flutter after IV bisphosphonate was not observed in orally treated patients.

Effect of Anastrozole on Bone-Mineral Density

Five years of anastrozole therapy did not lead to osteoporosis for any woman with normal BMD at baseline.

A Bad Break in Epilepsy?

  • Psychiatry
  • Summary and Comment
  • Subscription required

Deficits in bone mineral density are found in children with epilepsy, and these deficits worsen as illness duration increases.

Healthcare Expenditures for Spine Problems Have Increased

At the same time, patient functioning has decreased.

Oral Bisphosphonates and Oral Health

Oral BP administration was not associated with increased risk for ONJ.

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