Aging / Geriatrics
The latest information on gerontology — summaries and comments on Alzheimer Disease, arthritis, dementia, Parkinson Disease, and more — from across our primary care and specialty care areas. Sign up now for monthly e-mail alerts on new content.
SUMMARY AND COMMENT
Trends in In-Hospital CPR in Elders
- July 1, 2009
- Allan S. Brett, MD
- General Medicine
A rising proportion of hospital deaths are preceded by CPR.
- Reviewing:
- Ehlenbach WJ et al. N Engl J Med 2009 Jul 2; 361:22
SUMMARY AND COMMENT
Previously Unknown Protein Contributes to Huntington Disease
- June 30, 2009
- Anthony L. Komaroff, MD
- General Medicine
Although the mutant protein that causes HD is known, targeting it is difficult; a newly discovered cofactor might be an easier goal.
- Reviewing:
- Subramaniam S et al. Science 2009 Jun 5; 324:1327
SUMMARY AND COMMENT
Worrying About Alzheimer Disease? Don’t!
- June 29, 2009
- Steven Dubovsky, MD
- Psychiatry
In this animal model of AD, chronic stress worsened the impact of amyloid-β on learning, memory, and electrophysiologic response.
- Reviewing:
- Srivareerat M et al. Biol Psychiatry 2009 Jun 1; 65:918
SUMMARY AND COMMENT
BP-Lowering Drugs and Prevention of Cardiovascular DiseaseFree
- June 25, 2009
- Paul S. Mueller, MD, MPH, FACP
- General Medicine
All five classes of BP-lowering drugs were effective, regardless of patients’ histories.
- Reviewing:
- Law MR et al. BMJ 2009 May 19; 338:b1665
SUMMARY AND COMMENT
The Search Continues for Effective Nonhormonal Therapies for Hot Flashes
- June 25, 2009
- Robert W. Rebar, MD
- General Medicine
Acupuncture and a Chinese herbal combination resulted in modest reductions in hot flash frequency.
- Reviewing:
- Borud EK et al. Menopause 2009 May/Jun; 16:484
SUMMARY AND COMMENT
Dosing of Influenza Vaccine in Older Adults: More Is Better
- June 24, 2009
- Larry M. Baddour, MD
- Infectious Diseases
Phase III trial data further support the use of high-dose influenza vaccine in older adults.
- Reviewing:
- Falsey AR et al. J Infect Dis 2009 Jul 15; 200:172
SUMMARY AND COMMENT
CT Colonography in Patients at Elevated Risk for Colorectal Cancer
- June 23, 2009
- Thomas L. Schwenk, MD
- General Medicine
Results were accurate in most high-risk patients.
- Reviewing:
- Regge D et al. JAMA 2009 Jun 17; 301:2453
SUMMARY AND COMMENT
The Environment and Depressive Symptoms in Older Adults
- June 22, 2009
- Joel Yager, MD
- Psychiatry
Neighborhood characteristics may contribute to risk for depressive symptoms.
- Reviewing:
- Beard JR et al. Am J Public Health 2009 Jul; 99:1308
SUMMARY AND COMMENT
Inhibit Histone Deacetylase Type 2 to Improve Memory?
- June 22, 2009
- Barbara Geller, MD
- Psychiatry
Results from an animal study might indicate a new research avenue.
- Reviewing:
- Guan J-S et al. Nature 2009 May 7; 459:55
ASCO 2009 Report: Genitourinary Cancer
- June 16, 2009
- Robert Dreicer, MD, MS, FACP
- Oncology and Hematology
Trial results of new treatments for prostate, urothelial, and renal cancers
