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Search for systemic lupus erythematosus in all Journal Watch editions
Physician-authored summaries on the latest research on systemic lupus erythematosus, editorials on systemic lupus erythematosus, and perspectives on systemic lupus erythematosus - drawn from the top medical journals.
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You searched for: systemic lupus erythematosus
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The Significance of Discoid Lupus Erythematosus in Patients with Systemic LE
- April 12, 2013
- Jeffrey P. Callen, MD
- Dermatology
The presence of discoid lupus erythematosus lesions in patients with systemic LE represents a more benign subset of otherwise unselected SLE patients.- Reviewing:
- Merola JF et al., J Am Acad Dermatol 2013 Mar 29;:
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Genetic Trade-Off — Systemic Lupus Erythematosus or Cerebral Malaria
- January 12, 2011
- Richard T. Ellison III, MD
- Infectious Diseases
A study in mice suggests that genetic susceptibility to SLE protects against cerebral malaria.- Reviewing:
- Waisberg M et al., Proc Natl Acad Sci U S A 2010 Dec 27;:
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Antimalarial Therapy Protects Patients with Lupus Erythematosus Against Thrombovascular Disease
- April 23, 2010
- Jeffrey P. Callen, MD
- Dermatology
Routine use of antimalarial drugs may be warranted in patients with systemic LE.- Reviewing:
- Jung H et al., Arthritis Rheum 2010 Mar; 62:863.
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Excellent Risk-Benefit Profile of Antimalarials in Treatment of Lupus
Results of a systematic review support use of antimalarials in patients with SLE during the entire course of the disease.- Reviewing:
- Ruiz-Irastorza G et al., Ann Rheum Dis 2009 Jun 4;:
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Long-Term Clinical and Immunological Effects of Anti-CD20 Treatment in Refractory SLE
- June 24, 2008
- Deborah M. DeMarco, MD
- General Medicine
Anti-CD20 treatment could be beneficial for treatment of patients with refractory lupus nephritis and autoimmune cytopenias.- Reviewing:
- Lindholm C et al., J Rheumatol 2008 May; 35:826.
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Unraveling the Genetic Predisposition to Systemic Lupus Erythematosus Free
- February 27, 2008
- Jeffrey P. Callen, MD
- Dermatology
A collection of studies and commentary focus on the identification of genetic defects associated with risk for SLE.- Reviewing:
- Hom G et al., N Engl J Med 2008 Feb 28; 358:900. Kozyrev SV et al., Nat Genet 2008 Feb; 40:211. Nath SK et al., Nat Genet 2008 Feb; 40:152. International Consortium for Systemic Lupus Erythematosus Genetics (SLEGEN)., Nat Genet 2008 Feb; 40:204. Crow MK., N Engl J Med 2008 Feb 28; 358:956. Maier LM and Hafler DA., Nat Genet 2008 Feb; 40:131. Rahman A and Isenberg DA., N Engl J Med 2008 Feb 28; 358:929.
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High Serum IFN-α Is a Heritable Risk Factor for Systemic Lupus Erythematosus
- October 3, 2007
- Jeffrey P. Callen, MD
- Dermatology
Healthy family members of patients with SLE had elevated levels of IFN-α activity.- Reviewing:
- Niewold TB et al., Genes Immun 2007 Sep; 8:492.
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Does Antimalarial Therapy Delay SLE Onset?
- October 3, 2007
- Jeffrey P. Callen, MD
- Dermatology
The short answer is yes, but care should accompany treatment, which is not without risk.- Reviewing:
- James JA et al., Lupus 2007 Jun; 16:401.
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Vaccinations in Patients with SLE
- November 28, 2006
- Deborah M. DeMarco, MD
- General Medicine
Findings from a review study suggest that immunization with inactivated vaccines is safe and effective for most patients with systemic lupus erythematosus.- Reviewing:
- O’Neill SG and Isenberg DA., Lupus 2006 Nov; 15:778-83.
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The Impact of Vasculitis in Systemic Lupus Erythematosus
- May 23, 2006
- Jeffrey P. Callen, MD
- Dermatology
Investigators characterized the nature and impact of blood vessel inflammation in a large group of patients with SLE.- Reviewing:
- Ramos-Casals M et al., Medicine (Baltimore) 2006 Mar; 85:95-104.
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Poor Pregnancy Outcomes Before and After Diagnosis of SLE
- November 8, 2005
- Robert W. Rebar, MD
- General Medicine
Although the adverse effects of systemic lupus erythematosus (SLE) on pregnancy outcomes (i.e., fetal wasting, preterm birth, fetal growth restriction) have been well documented, less . . .- Reviewing:
- Dhar JP et al., Am J Obstet Gynecol 2005 Oct; 193:1444-55.
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Does HT Exacerbate Lupus?
- October 4, 2005
- Anna Wald, MD, MPH
- Women's Health
Increased risk for systemic lupus erythematosus (SLE) among women of childbearing age, combined with data from observational studies, has raised concerns about exacerbations of SLE . . .- Reviewing:
- Buyon JP et al., Ann Intern Med 2005 Jun 21; 142:953-62.
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Does Estrogen Replacement Cause Lupus Flares?
- July 19, 2005
- Richard Saitz, MD, MPH, FACP, FASAM
- General Medicine
Hormone therapy might not cause severe lupus flares, but it is associated with potential risks and adverse events in SLE patients.- Reviewing:
- Buyon JP et al., Ann Intern Med 2005 Jun 21; 142:953-62.
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Autoantibody Formation Precedes Development of Systemic Lupus Erythematosus
- November 12, 2003
- Jeffrey P. Callen, MD
- Dermatology
Autoantibodies develop over time, and their presence in asymptomatic patients may presage clinical disease.- Reviewing:
- Arbuckle MR et al., N Engl J Med 2003 Oct 16; 349:1526-33. Shmerling RH., N Engl J Med 2003 Oct 16; 349:1499-500.
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DNASE1 and Systemic Lupus Erythematosus
- December 11, 2001
- Hensin Tsao, MD, PhD
- Dermatology
Researchers have long suspected a strong genetic predisposition to the development of systemic lupus erythematosus (SLE). Most genes identified as having a role in SLE, . . .- Reviewing:
- Yasutomo K et al., Nat Genet 2001 Aug; 28:
313 314 .
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Clinical Expression of Systemic Lupus Erythematosus Differs with Age of Onset
- June 1, 1993
- Johnson
- Dermatology
Systemic lupus erythematosus (SLE) affects an estimated 300,000 persons in the U.S., making it a relatively common disease. Because any single or combination of organ . . .- Reviewing:
- Cervera R et al., Medicine 1993; 72:
113 124 .
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First Guidelines Issued on Managing Lupus Nephritis Free
- May 4, 2012
- Physician's First Watch
The first guidelines on managing nephritis in patients with systemic lupus erythematosus have been issued by the American College of Rheumatology. Among the recommendations, published... -
UVA1 Is Often A1! Free
- April 27, 2012
- Mark V. Dahl, MD
- Dermatology
After reviewing the evidence, a workshop group discusses the effectiveness, safety, and costs of UVA1 phototherapy.- Reviewing:
- Kerr AC et al., Clin Exp Dermatol 2012 Apr; 37:219.
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Briefly Noted
- February 10, 2012
- Jeffrey P. Callen, MD
- Dermatology
Increased cardiovascular risk associated with psoriasis, protective effects of cutaneous discoid lupus, treatment for erosive pustular scalp dermatosis, and quality of life in patients with CLE-induced photosensitivity -
Nonbullous Neutrophilic Lupus Erythematosus – The Real Deal or a Variant of Neutrophilic Dermatosis?
- January 27, 2012
- Jeffrey P. Callen, MD
- Dermatology
Our author considers it the latter.- Reviewing:
- Brinster NK et al., J Am Acad Dermatol 2012 Jan; 66:92.
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